217 results for "EZH2" in Products
EZH2 Products
KMT6 / EZH2 encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
EZH2 histone methyltransferase inhibitor
| Alternate Names: | DZNep,NSC 617989,HY-12186 |
| Chemical Name: | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC/IF |
Very high affinity and selective EZH2 inhibitor
| Chemical Name: | N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL11960 |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody (CL11960) [NBP3-15125]](https://resources.rndsystems.com/images/products/EZH2-KMT6-Antibody-CL11915-Immunohistochemistry-Paraffin-NBP3-15125-img0007.jpg "Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody (CL11960) [NBP3-15125]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL11915 |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-21204] -](https://resources.rndsystems.com/images/products/nbp3-21204_mouse-ezh2-kmt6-mab-cl11915-45202315531396.jpg "Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-21204] -")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL11945 |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/Immunofluorescence: EZH2/KMT6 Antibody [NBP3-21205] -](https://resources.rndsystems.com/images/products/nbp3-21205_mouse-ezh2-kmt6-mab-cl11945-45202315463313.jpg "Immunocytochemistry/Immunofluorescence: EZH2/KMT6 Antibody [NBP3-21205] -")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL11915 |
| Applications: | IHC, WB, ICC/IF |
![EZH2/KMT6 Antibody (CL11915) - Azide and BSA Free Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-44326]](https://resources.rndsystems.com/images/products/nbp3-44326_mouse-ezh2-kmt6-mab-cl11915-azide-and-bsa-free-282202512195419.jpg "Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-44326]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL11960 |
| Applications: | IHC, WB, ICC/IF |
![EZH2/KMT6 Antibody (CL11960) - Azide and BSA Free Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-44355]](https://resources.rndsystems.com/images/products/nbp3-44355_mouse-ezh2-kmt6-mab-cl11960-azide-and-bsa-free-28220251273741.jpg "Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-44355]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL11945 |
| Applications: | IHC, ICC/IF |
![EZH2/KMT6 Antibody (CL11945) - Azide and BSA Free Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-44327]](https://resources.rndsystems.com/images/products/nbp3-44327_mouse-ezh2-kmt6-mab-cl11945-azide-and-bsa-free-282202512111820.jpg "Immunohistochemistry-Paraffin: EZH2/KMT6 Antibody [NBP3-44327]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #9Q2R9 |
| Applications: | IHC, WB |
3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
| Chemical Name: | (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #6G4F4 |
| Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
![Western Blot: EZH2/KMT6 Antibody (6G4F4)BSA Free [NBP2-52463]](https://resources.rndsystems.com/images/products/EZH2-KMT6-Antibody-6G4F4-Western-Blot-NBP2-52463-img0007.jpg "Western Blot: EZH2/KMT6 Antibody (6G4F4)BSA Free [NBP2-52463]")
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, ChIP |
![Western Blot: EZH2/KMT6 Antibody [NBP2-17087]](https://resources.rndsystems.com/images/products/KMT6-EZH2-Antibody-Western-Blot-NBP2-17087-img0001.jpg "Western Blot: EZH2/KMT6 Antibody [NBP2-17087]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #EZH2/2536 |
| Applications: | WB, ELISA, Flow, ICC/IF, MA |
![Western Blot: EZH2/KMT6 Antibody (EZH2/2536) [NBP3-07187]](https://resources.rndsystems.com/images/products/EZH2-KMT6-Antibody-EZH2-2536-Western-Blot-NBP3-07187-img0002.jpg "Western Blot: EZH2/KMT6 Antibody (EZH2/2536) [NBP3-07187]")
| Reactivity: | Human |
| Details: | Mouse IgG Kappa Monoclonal Clone #EZH2/6988 |
| Applications: | IHC, WB, ELISA, Flow |
Potent and selective EZH2/EZH1 inhibitor
| Chemical Name: | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-(1-methylethyl)-1-piperazinyl]-3-pyridinyl]-1H-indazole-4-carboxamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG Kappa Monoclonal Clone #EZH2/6988 |
| Applications: | IHC, WB, ELISA, Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit IgG Monoclonal Clone #PSH04-14 |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, ChIP, Mycoplasma |
![Western Blot: EZH2/KMT6 Antibody [NBP2-59251]](https://resources.rndsystems.com/images/products/EZH2-KMT6-Antibody-Western-Blot-NBP2-59251-img0002.jpg "Western Blot: EZH2/KMT6 Antibody [NBP2-59251]")
Potent and selective SAM-competitive EZH2 inhibitor
| Chemical Name: | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide |
| Purity: | ≥98% |
Potent and selective SAM-competitive EZH2 inhibitor
| Chemical Name: | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide |
| Purity: | ≥98% |
Highly potent and SAM-competitive EZH2 inhibitor
| Chemical Name: | 5,8-Dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-1(2H)-isoquinolinone acetate |
| Purity: | ≥97% |
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, MA, PAGE |
![SDS-PAGE: Recombinant Human EZH2/KMT6 GST (N-Term) Protein [H00002146-P01]](https://resources.rndsystems.com/images/products/Recombinant-Human-EZH2-KMT6-Protein-SDS-Page-H00002146-P01-img0001.jpg "SDS-PAGE: Recombinant Human EZH2/KMT6 GST (N-Term) Protein [H00002146-P01]")
Polycomb repressive complex 2 (PRC2) Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((S)-2-(4-(4-(5-((Furan-2-ylmethyl)amino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)benzamido)butanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
Potent and selective EZH2 inhibitor
| Chemical Name: | N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-carboxamide |
| Purity: | ≥97% |
