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271 results for "IL-1 RI" in Products
IL-1 RI Products
IL-1 RI, also known as the type 1 IL-1 receptor and CD121a, is a transmembrane protein in the Toll/IL-1 R (TIR) superfamily. IL-1 RI binds the pleiotropic cytokines IL-1 alpha and IL-1 beta, plus the IL-1 receptor antagonist (IL-1 Ra). Signal transduction requires complex formation with IL-1 R AcP/IL-1 R3. This complex recruits the adaptor protein MyD88, to initiate signaling in the NF kappa B pathway. IL-1 RI is expressed predominantly by T cells, fibroblasts, and endothelial cells and mediates acute phase inflammatory responses including fever.
| Reactivity: | Human |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, B/N |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, B/N, Flow, CyTOF-ready |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #35730 |
| Applications: | WB, ELISA(Cap) |
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| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P14778 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #JAMA-147 |
| Applications: | B/N, Flow, IP |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
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| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #129304 |
| Applications: | WB, Flow, CyTOF-ready |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
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| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | P13504 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Assay Range: | 125-8000 pg/mL |
| Applications: | ELISA |
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| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #732210 |
| Applications: | WB |
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| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #129301 |
| Applications: | WB |
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| Reactivity: | Mouse |
| Details: | Hamster IgG Monoclonal Clone #JAMA147 |
| Applications: | B/N |
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| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | P14778.1 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #JAMA-147 |
| Applications: | B/N, Flow, IP, CyTOF-ready |
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| Reactivity: | Rat |
| Source: | NS0 |
| Accession #: | Q02955 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Assay Range: | 93.8-6000 pg/mL |
| Applications: | ELISA |
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| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #129304 |
| Applications: | Flow |
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Potent, selective human type I IL-1 receptor antagonist
| Purity: | ≥95% |
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TIR-TIR interaction inhibitor
| Chemical Name: | 1-Methyl-2,5-bis[[[(1S)-2-methyl-1-(1-pyrrolidinylcarbonyl)propyl](3-phenylpropyl)amino]carbonyl]pyridinium iodide |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA(Det) |
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| Reactivity: | Human |
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