Irradiated Mouse Embryonic Fibroblasts: Products

Mouse embryonic fibroblasts are used to maintain and expand pluripotent human embryonic stem cells (hES) in an undifferentiated state, or to induce differentiation along somatic or germ cell lineages. R&D Systems iMEFs (Catalog # PSC001) are mitotically inactivated by irradiation rather than using pharmacological inhibitors, thus eliminating possible exposure of your embryonic stem cells to toxic agents.

Each of irradiated mouse embryonic fibroblasts is confirmed negative for mycoplasma contamination using the MycoProbe® mycoplasma detection kit (Catalog # CUL001B) and negative for microbial contamination. Furthermore, each lot is tested for its ability to support undifferentiated growth of the BG01V human embryonic stem cell line as assessed by Oct-4 and SSEA-4 expression.