6 results for "MCT1/SLC16A1 Small Molecules and Peptides" in Products

MCT1/SLC16A1 Small Molecules and Peptides

MCT1/SLC16A1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. SLC16A1 may be a potential therapeutic target combining antimetabolic and anti-angiogenic activ...

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Potent MCT1 inhibitor

Chemical Name: 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one
Purity: ≥98%
Potent MCT1 inhibitor
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MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells

Chemical Name: 6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
Purity: ≥98%
MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells
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MCT1 inhibitor; also inhibits hexokinase II

Chemical Name: 3-Bromo-2-oxopropanoic acid
MCT1 inhibitor; also inhibits hexokinase II
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MCT1 inhibitor

Chemical Name: 5-[[(3R)-3-Hydroxy-1-pyrrolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-6-(4-quinolinylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
Purity: ≥98%
MCT1 inhibitor
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MCT inhibitor; also inhibits mitochondrial pyruvate carrier

Chemical Name: 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid
Purity: ≥98%
MCT inhibitor; also inhibits mitochondrial pyruvate carrier
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MCT inhibitor; decreases glycoloysis

Chemical Name: 2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid
Purity: ≥98%
MCT inhibitor; decreases glycoloysis
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