20 results for "molecular-glues&view=expanded" in Products

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dCeMM2

Catalog #: 7525
Product Documents

Molecular glue Degrader; induces ubiquitination and degradation of cyclin K

Chemical Name: N-(5-Chloro-2-pyridinyl)-2-(5H-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide
Purity: ≥98%
Molecular glue Degrader; induces ubiquitination and degradation of cyclin K

NCT 02

Catalog #: 7551
Product Documents

Molecular glue; induces degradation of CCNK and CDK12

Chemical Name: 6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5H-indeno[5,6-b]furan-3-acetamide
Purity: ≥98%
Molecular glue; induces degradation of CCNK and CDK12

SJ 6986

Catalog #: 7720
Product Documents

Molecular glue; induces degradation of GSPT1/2

Chemical Name: N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-2-(trifluoromethoxy)benzenesulfonamide
Purity: ≥98%
Molecular glue; induces degradation of GSPT1/2

CCT 369260

Catalog #: 7799
Product Documents

Molecular glue; induces degradation of BCL6

Chemical Name: rel-5-[[5-Chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethyl-1-piperidinyl]-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-2H-benzimidazol-2-one
Purity: ≥98%
Molecular glue; induces degradation of BCL6

NRX 252114

Catalog #: 7990
Product Documents

Molecular glue Degrader of mutant β-catenin

Chemical Name: 2-[[4-[(2,6-Dichlorophenyl)thio]-1,2-dihydro-2-oxo-6-(trifluoromethyl)-3-pyridinyl]carbonyl]-2,3-dihydro-1H-isoindole-4-carbonitrile
Purity: ≥98%
Molecular glue Degrader of mutant β-catenin

IBG3

Catalog #: 8129
Product Documents

Potent molecular glue Degrader of BET proteins BRD4 and BRD2

Chemical Name: tert-Butyl 2-((S)-4-(4-((4'-((S)-6-(2-(tert-butoxy)-2-oxoethyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-[1,1'-biphenyl]-4-carboxamido)methyl)phenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
Published vs Bio-Techne batch comparison for IBG3
(2)

SJ 3149

Catalog #: 8141
Product Documents

Potent and selective CK1α molecular glue Degrader

Chemical Name: 3-(5-(Benzo[d]isoxazol-3-ylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Purity: ≥98%
Potent and selective CK1α molecular glue Degrader

VVD 065

Catalog #: 8875
Product Documents

Covalent allosteric NRF2 inhibitor

Chemical Name: 1-[(3R)-3-[3-(4-Amino-1,3,5-triazin-2-yl)-5-chlorophenyl]-4-morpholinyl]-2-propen-1-one
Purity: ≥98%
Covalent allosteric NRF2 inhibitor

NK 7-902

Catalog #: 8926
Product Documents

Potent and selective NEK7 molecular glue degrader

Chemical Name: 2-(2,6-Dioxopiperidin-3-yl)-5-[(1S,2R,5S)-2-(ethylamino)-8-azabicyclo[3.2.1]octan-8-yl]isoindole-1,3-dione
Purity: ≥98%
Potent and selective NEK7 molecular glue degrader

NX 1607

Catalog #: 8950
Product Documents

CBL-B intramolecular glue inhibitor

Chemical Name: 2,3-Dihydro-2-[3-[cis-3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl]phenyl]-6-[[(3S)-3-methyl-1-piperidinyl]methyl]-4-(trifluoromethyl)-1H-isoindol-1-one
Purity: ≥98%
CBL-B intramolecular glue inhibitor
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