7 results for "Nav1.7" in Products
Nav1.7 Products
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (from SwissProt).
Cardiac Na+ channel blocker. Antiarrhythmic
| Chemical Name: | N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate |
| Purity: | ≥98% |
Na+ channel blocker; antiarrhythmic agent
| Alternate Names: | Ko 1173 |
| Chemical Name: | 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride |
| Purity: | ≥98% |
NaV channel blocker
| Chemical Name: | N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide |
| Purity: | ≥98% |
NaV blocker; neuroprotective
| Alternate Names: | 619C89 |
| Chemical Name: | 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine |
| Purity: | ≥98% |
Inhibitor of neuronal NaV channels; anticonvulsant
| Alternate Names: | CBZ |
| Chemical Name: | 5H-Dibenz[b,f]azepine-5-carboxamide |
| Purity: | ≥98% |
Potent and selective Nav1.7 channel blocker
| Chemical Name: | 4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate |
| Purity: | ≥98% |
Potent and selective Nav1.7 blocker; analgesic
| Chemical Name: | 4-[[1-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methoxy]-5-cyclopropyl-2-fluoro-N-(methylsulfonyl)benzamide |
| Purity: | ≥98% |
