10 results for "NFkB1 Small Molecules and Peptides" in Products

NFkB1 Small Molecules and Peptides

NFkB1 (NFkB p50) and NFkB2 (NFkB p52) are class I members of the Rel/NFkB family of transcription factors that also includes RelA, c-Rel and RelB. Rel/NFkB members regulate expression of genes that participate in immune, apoptotic and oncogenic processes. Class I members lack a C-terminal transcriptional activation segment found in class II members...

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Proteasome and calpain inhibitor. Inhibits NF-κB activation

Alternate Names: Z-LLL-al,Z-Leu-Leu-Leu-CHO
Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
Purity: ≥95%
Proteasome and calpain inhibitor. Inhibits NF-κB activation
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KDM4A inhibitor; also NF-κB activator

Alternate Names: D-α-hydroxyglutaric acid disodium salt
Chemical Name: (R)-2-Hydroxypentanedioic acid disodium salt
KDM4A inhibitor; also NF-κB activator
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Specific inhibitor of NF-κB activation

Alternate Names: CAPE
Chemical Name: 3-(3,4-Dihydroxyphenyl)-2-propenoic acid 2-phenylethyl ester
Purity: ≥98%
Specific inhibitor of NF-κB activation
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Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

Chemical Name: (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
Purity: ≥98%
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
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Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist

Chemical Name: (+)-(3β)-3-Hydroxylup-20(29)-en-28-oic acid
Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist
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Inhibitor of NF-κB activation; anti-inflammatory

Chemical Name: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
Purity: ≥98%
Inhibitor of NF-κB activation; anti-inflammatory
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Inhibits TNF-α-induced NF-κB activation

Chemical Name: (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid
Purity: ≥98%
Inhibits TNF-α-induced NF-κB activation
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Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1

Chemical Name: 5-[[4-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid
Purity: ≥97%
Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1
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NF-κB and AP-1 dual inhibitor

Chemical Name: N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide
Purity: ≥98%
NF-κB and AP-1 dual inhibitor
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Potent 20S proteasome inhibitor

Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide
Purity: ≥98%
Potent 20S proteasome inhibitor
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