8 results for "Nicotinic Acetylcholine R alpha 4/CHRNA4" in Products
Nicotinic Acetylcholine R alpha 4/CHRNA4 Products
CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. CHRNA4 is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in CHRNA4 cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in CHRNA4 that provide protection against nicotine addiction have been described.
Potent and selective neuronal nAChRagonist
| Chemical Name: | (1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one |
| Purity: | ≥99% |
Selective α4β2 nAChR partial agonist; orally active
| Chemical Name: | 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine tartrate |
| Purity: | ≥99% |
Selective α4β2 nAChR agonist
| Alternate Names: | Metanicotine,TC-2403 |
| Chemical Name: | (E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine oxalate |
| Purity: | ≥99% |
Selective α4β2 nAChR partial agonist
| Chemical Name: | 4-(5-ethoxy-3-pyridinyl)-N-methyl-(3E)-3-buten-1-amine difumarate |
| Purity: | ≥98% |
Potent α4β4, α4β2 and α7 nAChR agonist
| Chemical Name: | (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one |
| Purity: | ≥98% |
High affinity and selective α4β2 nAChR partial agonist
| Chemical Name: | 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride |
| Purity: | ≥98% |
High affinity and subtype-selective α6β2 and α4β2 nAChR partial agonist
| Chemical Name: | (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one |
| Purity: | ≥98% |
Selective α4β2 nAChR agonist
| Alternate Names: | Tebanicline |
| Chemical Name: | (R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride |
| Purity: | ≥98% |
