7 results for "Nicotinic Acetylcholine R alpha 7/CHRNA7" in Products
Nicotinic Acetylcholine R alpha 7/CHRNA7 Products
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. nAChR alpha 7/CHRNA7 forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once nAChR alpha 7/CHRNA7 binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Selective α7 nAChR agonist
| Chemical Name: | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide |
| Purity: | ≥98% |
Potent and selective α7 nAChR agonist
| Chemical Name: | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamide hydrochloride |
| Purity: | ≥98% |
Selective α7 nAChR agonist
| Chemical Name: | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate |
| Purity: | ≥98% |
α7 nAChR partial agonist
| Chemical Name: | 2-[2-(4-Bromophenyl)-2-oxoethyl]-1-methylpyridinium iodide |
| Purity: | ≥98% |
Potent α4β4, α4β2 and α7 nAChR agonist
| Chemical Name: | (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one |
| Purity: | ≥98% |
α7 nAChR partial agonist
| Chemical Name: | Octahydro-2-methyl-5-(6-phenyl-3-pyridazinyl)-pyrrolo[3,4-c]pyrrole |
| Purity: | ≥98% |
Selective α7 nAChR partial agonist
| Chemical Name: | 4-Bromophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate hydrochloride |
| Purity: | ≥98% |
