5 results for "P2X1/P2RX1 Small Molecules and Peptides" in Products
P2X1/P2RX1 Small Molecules and Peptides
Biologic responses to ATP, ADP, and other extracellular nucleotides are mediated by P2-nucleotide receptors belonging to 2 major classes: G protein-coupled P2Y receptors and nucleotide-gated ion channel P2X receptors. P2RX1 functions as a ligand-gated ion channel with relatively high calcium permeability. Mouse studies suggest that this receptor is essential for normal male reproductive function. The development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
| Chemical Name: | 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt |
| Purity: | ≥95% |
Highly selective P2X1 antagonist
| Chemical Name: | 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt |
| Purity: | ≥90% |
Selective P2Y11 and P2X1 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥90% |
Potent and selective P2X1 antagonist
| Chemical Name: | 8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥95% |
Selective and competitive P2X1 antagonist
| Chemical Name: | 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid, hexasodium salt |
