6 results for "p38 delta" in Products

p38 delta Products

The p38 Mitogen-activated Protein Kinases (MAPKs) are a family of four related Ser/Thr kinases activated by proinflammatory cytokines and environmental stresses. All four p38 family members, alpha, beta, gamma, and delta, are phosphorylated by MKK3 and/or MKK6 at dual Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr. Once activated, p38 phosphorylates a number of targets, including the nuclear transcription factors ATF2 and Max.

The most frequently analyzed family ...

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Potent, selective inhibitor of MEK1 and 2

Chemical Name: 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene
Potent, selective inhibitor of MEK1 and 2
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Selective inhibitor of p38 MAPK

Alternate Names: Adezmapimod
Chemical Name: 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine
Purity: ≥98%
Selective inhibitor of p38 MAPK
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High affinity and selective p38 kinase inhibitor

Alternate Names: Doramapimod
Chemical Name: N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea
Purity: ≥98%
High affinity and selective p38 kinase inhibitor
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Selective MEK inhibitor

Alternate Names: CI-1040
Chemical Name: 2-[(2-Chloro-4-iodophenyl)amino]-N-cyclopropylmethoxy)-3,4-difluorobenzamide
Purity: ≥98%
Selective MEK inhibitor
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Src family kinase inhibitor; also inhibits c-Abl

Alternate Names: 1-NA-PP 1
Chemical Name: 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: ≥98%
Src family kinase inhibitor; also inhibits c-Abl
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p38 MAPK inhibitor

Chemical Name: N-Cyano-N'-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine
Purity: ≥98%
p38 MAPK inhibitor
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