6 results for "PDE6D Small Molecules and Peptides" in Products

PDE6D Small Molecules and Peptides

PDE6D is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system. The second messengers cAMP and cGMP are key regulatory molecules that are involved in a wide variety of signal transduction pathways, such as insulin secretion, platelet aggregation, smooth muscle relaxation, olfaction, and vision. Levels of cAMP and cGMP are regulated by their rate of synthesis by nucleotide cyclases and by their rate of hydrolysis by cyclic nucleotide phosphodiesterases ...

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PDE inhibitor (non-selective)

Chemical Name: 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity: ≥98%
PDE inhibitor (non-selective)
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GPR35 agonist

Chemical Name: 2-(2-Propyloxyphenyl)-8-azapurin-6-one
Purity: ≥98%
GPR35 agonist
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Adenosine transport inhibitor

Chemical Name: 2,6-bis(Diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
Purity: ≥98%
Adenosine transport inhibitor
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High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Chemical Name: 2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride
Purity: ≥98%
High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ
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Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma

Chemical Name: 4-[3-Fluoro-4-[[[[4-(1,1,2,2,2-pentafluoroethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Purity: ≥98%
Inhibitor of mutant β-catenin signaling in hepatocellular carcinoma
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PDEδ autophagy-tethering compound (ATTEC) Degrader

Chemical Name: N-(6-(2-(2,6-Dibromo-4-((5-iodo-2-oxoindolin-3-ylidene)methyl)phenoxy)acetamido)hexyl)-4-(3,4-dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide
Purity: ≥98%
PDEδ autophagy-tethering compound (ATTEC) Degrader
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