7 results for "RAR gamma/NR1B3 Small Molecules and Peptides" in Products

RAR gamma/NR1B3 Small Molecules and Peptides

Retinoids can reverse various premalignant lesions as well as prevent some second primary tumors. The effects of retinoids are regulated by retinoic acid receptors (RAR) and retinoid X receptors, which act as ligand-activated transcription factors. Ligand-dependent transcriptional activation of RARs is a multistep process that ends with the forma...

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High affinity pan-RAR antagonist

Chemical Name: 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid
Purity: ≥98%
High affinity pan-RAR antagonist
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Retinoic acid analog; RARα agonist

Chemical Name: 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid
Purity: ≥98%
Retinoic acid analog; RARα agonist
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Potent RAR agonist

Chemical Name: 4-[(1E)-3-[3,5-bis(1,1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid
Purity: ≥98%
Potent RAR agonist
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Blocks retinoic acid metabolism

Alternate Names: R-75251
Chemical Name: 5-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazole dihydrochloride
Purity: ≥98%
Blocks retinoic acid metabolism
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Synthetic retinoid; induces differentiation of stem cells

Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid
Purity: ≥99%
Synthetic retinoid; induces differentiation of stem cells
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Selective RARγ agonist

Chemical Name: 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic acid
Purity: ≥95%
Selective RARγ agonist
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Potent and selective RARγ agonist

Chemical Name: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid
Purity: ≥98%
Potent and selective RARγ agonist
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