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2 results for "Transcriptional Cyclin-dependent Kinase Degraders" in Products
Transcriptional Cyclin-dependent Kinase Degraders
As well as regulating progression through the cell cycle, some cyclin-dependent kinases (CDKs) play a key role in controlling transcription of DNA to produce an RNA template. While some CDKs are involved in both processes, such as CDK1 and CDK2, several CDKs only function in control of transcription and are called Transcriptional CDKs. This group includes CDK7, CDK8, CDK9, CDK10, CDK11, CDK12, CDK13 and CDK20. Cyclins that regulate transcriptional CDKs do not fluctuate in expression levels ...
Molecular glue Degrader; induces ubiquitination and degradation of cyclin K
| Chemical Name: | N-(5-Chloro-2-pyridinyl)-2-(5H-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide |
| Purity: | ≥98% |
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Molecular glue; induces degradation of CCNK and CDK12
| Chemical Name: | 6,7-Dihydro-N-(5-methyl-2-thiazolyl)-5H-indeno[5,6-b]furan-3-acetamide |
| Purity: | ≥98% |
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