8 results for "VEGFR1, VEGFR2, VEGFR3" in Products

VEGFR1, VEGFR2, VEGFR3 Products

VEGFR1 (Flt-1), VEGFR2 (KDR/Flk-1), and VEGFR3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, ang...

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VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Alternate Names: Semaxinib
Chemical Name: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Purity: ≥98%
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
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1 vial each of PE-conjugated anti-VEGF R1 (clone 49560), VEGF R2 (clone 89106), and VEGF R3 (clone 54733)

Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #89106, 49560, 54733
Applications: Flow
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Potent VEGFR-1, -2 and -3 inhibitor

Chemical Name: N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide
Purity: ≥98%
Potent VEGFR-1, -2 and -3 inhibitor
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Potent FGFR and VEGFR inhibitor

Alternate Names: PF-02969207,PNU-0290908
Chemical Name: 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid
Purity: ≥95%
Potent FGFR and VEGFR inhibitor
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Potent VEGFR, PDGFRβ and KIT inhibitor

Alternate Names: SU 11248
Chemical Name: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt
Purity: ≥98%
Potent VEGFR, PDGFRβ and KIT inhibitor
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Potent EGFR and VEGFR inhibitor

Chemical Name: 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Purity: ≥98%
Potent EGFR and VEGFR inhibitor
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Potent VEGFR inhibitor; also aromatase inhibitor

Alternate Names: CGP 79787D,PTK787/ZK222584
Chemical Name: N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate
Purity: ≥98%
Potent VEGFR inhibitor; also aromatase inhibitor
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Potent VEGFR inhibitor; also inhibits other RTKs

Alternate Names: Cabozantinib,BMS 907351
Chemical Name: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
Purity: ≥98%
Potent VEGFR inhibitor; also inhibits other RTKs
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