Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

R&D Systems | Catalog # PP-H5844-00

R&D Systems
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Western Blot, Direct ELISA, Immunoprecipitation

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # H5844
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Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

Application
Recommended Usage

Direct ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

5-15 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human myocardium

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using PP-H5844-00 in the following applications:

Formulation, Preparation, and Storage

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ERR alpha/NR3B1

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Ushers syndrome.

Long Name

Estrogen-related Receptor alpha

Alternate Names

ERR1, ESRL1, ESRRA, NR3B1

Entrez Gene IDs

2101 (Human)

Gene Symbol

ESRRA

Additional ERR alpha/NR3B1 Products

Product Documents for Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

For research use only

Citations for Human ERR alpha 1/NR3B1 Antibody (Clone H5844)

Customer Reviews for Human ERR alpha 1/NR3B1 Antibody (Clone H5844) (1)

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  • Human ERR alpha 1/NR3B1 Antibody (Clone H5844)
    Name: Anonymous
    Application: Western Blot
    Sample Tested: Liver tissue
    Species: Human
    Verified Customer | Posted 07/27/2021
    Human ERR alpha 1/NR3B1 Antibody (Clone H5844) PP-H5844-00

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Protocols

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