Nectin-2/CD112 Antibody (R2.525) - BSA Free

Novus Biologicals | Catalog # NBP3-09163

Clone R2.525 was used by HLDA to establish CD designation.
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Flow Cytometry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # R2.525

Format

BSA Free
View all Nectin-2/CD112 Primary Antibodies »

Product Specifications

Immunogen

NIH/3T3 cells transfected with human Nectin-2

Specificity

The mouse monoclonal antibody R2.525 recognizes an extracellular epitope on CD112, a type I transmembrane glycoprotein expressed by myelomonocytic and megakaryocytic cells, and by CD34+ hematopoietic progenitors.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Nectin-2/CD112 Antibody (R2.525) - BSA Free

Flow Cytometry: Nectin-2/CD112 Antibody (R2.525) - BSA Free [NBP3-09163]

Flow Cytometry: Nectin-2/CD112 Antibody (R2.525) - BSA Free [NBP3-09163]

Flow Cytometry: Nectin-2/CD112 Antibody (R2.525) [NBP3-09163] - Separation of human CD112 positive thrombocytes(red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD112 (R2.525) purified antibody (concentration in sample 9 ug/ml) GAM APC.
Flow Cytometry: Nectin-2/CD112 Antibody (R2.525) - BSA Free [NBP3-09163]

Flow Cytometry: Nectin-2/CD112 Antibody (R2.525) - BSA Free [NBP3-09163]

Flow Cytometry: Nectin-2/CD112 Antibody (R2.525) [NBP3-09163] - surface staining pattern of human peripheral whole blood stained using anti-human CD112 (R2.525) purified antibody (concentration in sample 9 ug/ml) GAM APC

Applications for Nectin-2/CD112 Antibody (R2.525) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nectin-2/CD112

Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

Poliovirus Receptor Related 2

Alternate Names

CD112, HVEB, MPH, Nectin2, PRR2, PVRL2

Gene Symbol

NECTIN2

Additional Nectin-2/CD112 Products

Product Documents for Nectin-2/CD112 Antibody (R2.525) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Nectin-2/CD112 Antibody (R2.525) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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