TAG-72 Antibody (B72.3 (Satumomab)) - Chimeric - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-52672

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, CyTOF-ready

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # B72.3 (Satumomab)

Format

Azide and BSA Free
View all TAG-72 Primary Antibodies »

Product Specifications

Immunogen

Tumour-associated glycoprotein 72 is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, and pancreatic cells.

Specificity

Recognises human Tumor associated glycoprotein 72.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for TAG-72 Antibody (B72.3 (Satumomab)) - Chimeric - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:10 - 1:500
Application Notes
This antibody is Cytof ready. This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques. A In-111-labeled, murine version of this antibody was used in immunoscintigraphy to detect colorectal cancers in patients. In 16 % of patients, human-anti-mouse-responses developed.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: TAG-72

Tumor-associated glycoprotein (TAG-72) is an oncofetal antigen with properties of a mucin. About 60% of carcinoma patients express TAG-72 in their sera. Majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for Ab-1 staining. Weak or no reactivity has been observed with most cell types of normal adult tissue excepting the secretory endometrium. Ab-1 is reportedly useful in distinguishing pulmonary adenocarcinomas (B72.3+) from pleural mesotheliomas (B72.3-).

Alternate Names

CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72, biosimilar antibody, biosimilars

Additional TAG-72 Products

Product Documents for TAG-72 Antibody (B72.3 (Satumomab)) - Chimeric - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for TAG-72 Antibody (B72.3 (Satumomab)) - Chimeric - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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