VCAM-1/CD106 Antibody - BSA Free

Name: VCAM-1/CD106 Antibody - BSA Free
Brand: Novus Biologicals
SKU: NBP2-38223
Price: 429 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-38223

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

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Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: IGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVRSEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit VCAM-1/CD106 Antibody - BSA Free (NBP2-38223) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for VCAM-1/CD106 Antibody - BSA Free

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223]

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223] - Analysis in human spleen and skeletal muscle tissues. Corresponding VCAM1 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223]

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223] - Staining of human spleen shows strong membranous positivity in cells in red pulp.

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223]

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223] - Staining of human Fallopian tube shows no positivity in glandular cells.

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223]

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223] - Staining of human pancreas shows no positivity in exocrine glandular cells or in islets of Langerhans.

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223]

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223] - Staining of human skeletal muscle shows no positivity in myocytes.

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223]

Immunohistochemistry-Paraffin: VCAM-1/CD106 Antibody [NBP2-38223] - Staining of human tonsil shows moderate membranous positivity in germinal center cells.

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Applications for VCAM-1/CD106 Antibody - BSA Free

Application

Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Application Notes

For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VCAM-1/CD106

CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 ( alpha4/ beta1 integrin) and LPAM-1 ( alpha4/ beta7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.

Long Name

Vascular Cell Adhesion Molecule 1

Alternate Names

CD106, VCAM1

Gene Symbol

VCAM1

UniProt

P19320

Additional VCAM-1/CD106 Products

Product Documents for VCAM-1/CD106 Antibody - BSA Free

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Product Specific Notices for VCAM-1/CD106 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.