24 results for "Compounds for NSC Differentiation" in 产品

Compounds for NSC Differentiation

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity: ≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)
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Adenylyl cyclase activator

Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity: ≥98%
Adult Stem Cell-derived Liver Organoids
(2)
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Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)
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Selective ALK2 inhibitor

Chemical Name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Purity: ≥98%
Selective ALK2 inhibitor
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FGFR1 and -3 inhibitor

Chemical Name: N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Purity: ≥98%
FGFR1 and -3 inhibitor
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Activator of LKB1/AMPK; antidiabetic agent

Chemical Name: N,N-Dimethylimidodicarbonimidic diamide hydrochloride
Activator of LKB1/AMPK; antidiabetic agent
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Forskolin synthesized to Ancillary Material Grade

Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity: ≥98%
Forskolin synthesized to Ancillary Material Grade
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PDE inhibitor (non-selective)

Chemical Name: 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity: ≥98%
PDE inhibitor (non-selective)
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Endogenous retinoic acid receptor agonist

Alternate Names: Tretinoin,ATRA
Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Purity: ≥98%
iPSC differentiation with retinoic acid
(2)
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Endogenous agonist of LPA1 and LPA2

Chemical Name: 1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt
Endogenous agonist of LPA1 and LPA2
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Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

Chemical Name: N-Cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide
Purity: ≥98%
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
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γ-secretase inhibitor; induces neuronal differentiation

Alternate Names: γ-Secretase Inhibitor XXI
Chemical Name: N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity: ≥98%
γ-secretase inhibitor; induces neuronal differentiation
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5-HT reuptake inhibitor

Chemical Name: N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenylpropylamine hydrochloride
Purity: ≥98%
5-HT reuptake inhibitor
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Selective GPR55 agonist; also promotes NSC proliferation and differentiation

Alternate Names: CID 20440433
Chemical Name: 3-[[4-(2,3-Dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide
Purity: ≥98%
Selective GPR55 agonist; also promotes NSC proliferation and differentiation
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DAPT synthesized to Ancillary Material Grade

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity: ≥99%
DAPT synthesized to Ancillary Material Grade
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Synthetic retinoid; induces differentiation of stem cells

Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid
Purity: ≥99%
Synthetic retinoid; induces differentiation of stem cells
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Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor
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Glutathione (GSH) precursor; maintains stem cell function in culture.

Chemical Name: (2R)-2-Acetamido-3-sulfanylpropanoic acid
Purity: ≥98%
Adult Stem Cell-derived Lung Organoids
(5)
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Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway

Chemical Name: 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
Purity: ≥98%
Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway
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Retinoic acid synthesized to Ancillary Material Grade

Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid
Purity: ≥98%
Retinoic acid synthesized to Ancillary Material Grade
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Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation

Chemical Name: 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol
Purity: ≥97%
Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation
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LDN 193189 synthesized to cGMP guidelines

Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥99%
LDN 193189 synthesized to cGMP guidelines
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Tankyrase (AKA PARP5) inhibitor; used to generate neurons from epiblast stem cells

Chemical Name: N-(Cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-1-piperidineacetamide
Purity: ≥98%
Tankyrase (AKA PARP5) inhibitor; used to generate neurons from epiblast stem cells
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Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water

Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥97%
Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water
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