34 results for "NMDA Receptor Antagonists Small Molecules and Peptides" in 产品
NMDA Receptor Antagonists Small Molecules and Peptides
NMDA receptors are expressed alongside AMPA receptors on the postsynaptic membrane of excitatory synapses, where they initiate a two-component excitatory postsynaptic potential (EPSP). The activation of AMPA receptors produces a current that has rapid onset and decay, while activation of NMDA receptors leads to a current with slower onset and decay. The slow decay of NMDA-mediated currents is due to the slow dissociation of glutamate from NMDA receptors, compared with AMPA receptors. Unlike ...
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
| Alternate Names: | 2-APV,D-APV,D-2-amino-5-phosphonovalerate |
| Chemical Name: | D-(-)-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥98% |
Potent and selective NMDA antagonist
| Alternate Names: | DL-APV |
| Chemical Name: | DL-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥98% |
Non-competitive NMDA antagonist; acts at ion channel site
| Alternate Names: | Dizocilpine |
| Chemical Name: | (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate |
| Purity: | ≥98% |
Potent and selective non-NMDA iGluR antagonist
| Alternate Names: | Cyanquixaline |
| Chemical Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione |
| Purity: | ≥98% |
Potent and selective NMDA antagonist; sodium salt of DL-AP5
| Chemical Name: | DL-2-Amino-5-phosphonopentanoic acid sodium salt |
| Purity: | ≥98% |
GluN2B-selective NMDA antagonist
| Chemical Name: | (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate |
| Purity: | ≥98% |
NMDA antagonist; acts at ion channel site
| Chemical Name: | 3,5-Dimethyl-tricyclo[3.3.1.13,7]decan-1-amine hydrochloride |
Potent kynurenine 3-monooxygenase (KMO) inhibitor
| Chemical Name: | 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide |
| Purity: | ≥98% |
Non-competitive NMDA antagonist; also σ ligand
| Chemical Name: | (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate |
| Purity: | ≥98% |
Potent competitive inhibitor of L-glutamate uptake
| Chemical Name: | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% |
Highly potent NMDA antagonist
| Chemical Name: | trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline |
| Purity: | ≥98% |
Potent NMDA antagonist; more active enantiomer of (RS)-CPP
| Chemical Name: | 3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid |
GluN1/GluN2A-selective NMDA antagonist
| Chemical Name: | 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide |
| Purity: | ≥98% |
NMDA antagonist; less active enantiomer of (+)-MK 801
| Chemical Name: | (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-imine maleate |
| Purity: | ≥98% |
Potent and selective NMDA antagonist; less active form of DL-AP5
| Chemical Name: | L-(+)-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥98% |
Potent NMDA antagonist
| Chemical Name: | (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid |
NMDA antagonist; acts at glycine site
| Chemical Name: | 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone |
| Purity: | ≥98% |
Potent competitive NMDA antagonist
| Chemical Name: | cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid |
Potent and selective NMDA antagonist; acts at glycine site
| Alternate Names: | PAMQX |
| Chemical Name: | [(1S)-1-[[(7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]phosphonic acid hydrochloride |
| Purity: | ≥98% |
Potent competitive NMDA antagonist
| Alternate Names: | Midafotel,SDZ EAA 494 |
| Chemical Name: | D-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid |
Potent and selective NMDA antagonist
| Chemical Name: | (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid |
| Purity: | ≥98% |
Potent and selective NMDA antagonist; acts at the glycine site
| Alternate Names: | GV 150526A |
| Chemical Name: | 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt |
| Purity: | ≥98% |
GluN2B-selective NMDA antagonist
| Alternate Names: | PD 174494,Ro 63-1908 |
| Chemical Name: | 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol hydrochloride |
| Purity: | ≥98% |
GluN2C/GluN2D-selective NMDA antagonist
| Chemical Name: | (2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid |
| Purity: | ≥98% |
KV7 channel activator; also GABAA modulator and indirect NMDA antagonist
| Alternate Names: | D 9998 |
| Chemical Name: | N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate |
| Purity: | ≥98% |
