Catalog Number: 1527
Chemical Name: (2S)-2-[[[5-(Trimethylstannyl)-3-pyridinyl]oxy]methyl]-1-azetidinecarboxylic acid, t-butyl ester
Biological Activity
Precursor to the highly potent and selective ligand for the α4β2 nicotinic receptor, 5-Iodo-A-85380 (Cat. No.1518). Suitable for radioiodination.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble in ethanol and in DMSO
  • Purity:
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. 2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling.
    Koren et al.
    J.Med.Chem., 1998;41:3690
  2. 5-Iodo-A-85380, an α4β2 subtype-selective ligand for nicotinic acetylcholine receptors.
    Mukhin et al.
    Mol.Pharmacol., 2000;57:642
Tocris Small Molecules
Description Application Cat# Citations Images  

5-Iodo-A-85380 dihydrochloride

1518 3  
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