ACPA (in Tocrisolve™ 100)
Chemical Name: N-(Cyclopropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Biological Activity
Potent and selective CB1 agonist (Ki = 2.2 nM), in water-soluble emulsion (for details see TocrisolveTM 100). Displays 325-fold selectivity over CB2 receptors and is active in vivo.ACPA, pure oil dissolved in ethanol and Tocrisolve Control also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Pharmacology of cannabinoid receptor ligands.
Pertwee
Curr.Med.Chem., 1999;6:635 -
Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1).
Hillard et al.
J.Pharmacol.Exp.Ther., 1999;289:1427 -
Cannabinoid CB1 receptor agonists produce cerebellar dysfunction in mice.
Patel et al.
2001 Symposium on the Cannabinoids, International, 2001;
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Citation for ACPA (in Tocrisolve™ 100)
The citations listed below are publications that use Tocris products. Selected citations for ACPA (in Tocrisolve™ 100) include:
1 Citation: Showing 1 - 1
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Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats.
Authors: Niu Et al.
Sleep 2012;153:2283
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