Catalog # Availability Size / Price Qty
Allopregnanolone | CAS No. 516-54-1 | GABA-A Receptor Modulators
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Description: Positive allosteric modulator of GABAA receptors
Alternative Names: 3a,5a-THPROG

Chemical Name: (3α,5α)-3-Hydroxy-pregnan-20-one

Product Details
Citations (5)
Supplemental Products

Biological Activity

Allopregnanolone is a GABAA receptor positive allosteric modulator. Neuroactive steroid.

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Background References

  1. Neurosteroids act on recombinant human GABAA receptors.
    Puia et al.
    Neuron, 1990;4:759
  2. Neurosteroids: endogenous regulators of the GABAA receptor.
    Belelli and Lambert
    Nat.Rev.Neurosci., 2005;6:565
  3. Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.
    Agis-Balboa et al.
    Proc.Natl.Acad.Sci.USA, 2006;103:14602

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Citations for Allopregnanolone

The citations listed below are publications that use Tocris products. Selected citations for Allopregnanolone include:

5 Citations: Showing 1 - 5


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