c-jun [p Thr93, p Thr91] Antibody (C-J 4C4/1) - BSA Free

Name: c-jun [p Thr93, p Thr91] Antibody (C-J 4C4/1) - BSA Free
Brand: Novus Biologicals
SKU: NB100-2748
Price: 349 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-2748

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Product Documents

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # C-J 4C4/1

Format

BSA Free

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Product Specifications

Immunogen

C-Jun phosphorylated at T91 and T93

Modification

p Thr91, p Thr93

Localization

Nuclear

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for c-jun [p Thr93, p Thr91] Antibody (C-J 4C4/1) - BSA Free

Application

Recommended Usage

ELISA

1:100 - 1:2000

Western Blot

1:100 - 1:2000

Application Notes

Positive control(s): NIH 3T3 cells treated with UV or anisomycin for 1 hour.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: c-Jun

The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Long Name

Cellular Repressor of E1A-stimulated Genes/Transcription Factor AP-1

Alternate Names

cJun, JUN

Entrez Gene IDs

3725 (Human); 24516 (Rat)

Gene Symbol

JUN

Additional c-Jun Products

Product Documents for c-jun [p Thr93, p Thr91] Antibody (C-J 4C4/1) - BSA Free

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Product Specific Notices for c-jun [p Thr93, p Thr91] Antibody (C-J 4C4/1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.