Calponin 1 Antibody (RM262)

Novus Biologicals | Catalog # NBP2-61504

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM262 expressed in HEK293
View all Calponin 1 Primary Antibodies »

Product Specifications

Immunogen

A peptide corresponding to the C-terminus of Human Calponin 1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Calponin 1 Antibody (RM262)

Western Blot: Calponin 1 Antibody (RM262) [NBP2-61504] -

Western Blot: Calponin 1 Antibody (RM262) [NBP2-61504] - Western Blot analysis of Mouse heart tissue lysates, using NBP2-61504, shows Calponin-1 expression
Calponin 1 Antibody (RM262)

Immunocytochemistry/Immunofluorescence: Calponin 1 Antibody (RM262) [NBP2-61504] -

Immunocytochemistry/Immunofluorescence: Calponin 1 Antibody (RM262) [NBP2-61504] - Immunocytochemistry of HeLa cells, using NBP2-61504 (red). Actin filaments have been labeled with fluorescein phalloidin (green), and nucleus stained with DAPI (blue).

Applications for Calponin 1 Antibody (RM262)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:200

Western Blot

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Calponin 1

Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in regulation of actomyosin as well as the regulation or modulation of contraction (1). Calponin binds filamentous actin (F-actin) through two distinct sites ABS1 and ABS2, with an affinity in the low micromolar range (2) Immunoreactivity for calponin, along with alpha-smooth muscle actin and smooth muscle myosin heavy chains, confirms the known neoplastic myoepithelial component of adenoid cystic carcinomas and epithelial-myoepithelial carcinomas. The consistently positive staining pattern in adenoid cystic carcinomas may be diagnostically useful in discriminating histologically similar but consistently negative polymorphous low-grade adenocarcinomas (3).

Alternate Names

Calponin H1, CNN1, Sm-Calp, SMCC

Gene Symbol

CNN1

Additional Calponin 1 Products

Product Documents for Calponin 1 Antibody (RM262)

Certificate of Analysis

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Product Specific Notices for Calponin 1 Antibody (RM262)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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