CCR4 Antibody

Novus Biologicals | Catalog # NB100-717

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Western Blot, ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Cited:

Immunohistochemistry-Frozen, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all CCR4 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide [SNYYLYESIPKPCTKEGIKAFGE] corresponding to amino acids 17-39 of the extracellular domain of human CCR4.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Monkey.

Localization

Cell membrane

Specificity

Peptide sequence is 50 % identical to other human chemokine receptors in this region.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CCR4 Antibody

Immunohistochemistry-Paraffin: CCR4 Antibody [NB100-717]

Immunohistochemistry-Paraffin: CCR4 Antibody [NB100-717]

Immunohistochemistry-Paraffin: CCR4 Antibody [NB100-717] - Section of human spleen.

Applications for CCR4 Antibody

Application
Recommended Usage

ELISA

1:30000

Flow Cytometry

1:12

Immunocytochemistry/ Immunofluorescence

1:400

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunohistochemistry-Paraffin

1:200

Western Blot

1:500
Application Notes
ICC/IF, IHC-F reactivity reported in (PMID: 23664188). Flow reactivity reported in (PMID: 15969628).

Flow Cytometry Panel Builder

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA.

Preservative

0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CCR4

Chemokine receptors are G protein-coupled receptors (GPCRs) that play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen.

Alternate Names

CD194

Entrez Gene IDs

1233 (Human)

Gene Symbol

CCR4

UniProt

P51679

Additional CCR4 Products

Product Documents for CCR4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CCR4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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