CD117/c-kit Antibody (CDX-0158) - Low Endotoxin, Azide and BSA Free

Name: CD117/c-kit Antibody (CDX-0158) - Low Endotoxin, Azide and BSA Free
Brand: Novus Biologicals
SKU: NBP3-28628
Price: 269 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-28628

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Flow Cytometry
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG₁ Clone # CDX-0158 expressed in CHO

Format

Low Endotoxin, Azide and BSA Free

View all CD117/c-kit Primary Antibodies »

Product Specifications

Immunogen

SCFR / c-Kit / CD117

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Description

The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Patent #: US20170073422A1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Scientific Data Images for CD117/c-kit Antibody (CDX-0158) - Low Endotoxin, Azide and BSA Free

ELISA: CD117/c-kit Antibody (CDX-0158)[NBP3-28628] -

Immobilized Human SCFR / c-Kit / CD117, His Tag at 2 μg/mL can bind CD117/c-kit Antibody (CDX-0158), The EC50 was approximately 0.02422 ug/mL.

Applications for CD117/c-kit Antibody (CDX-0158) - Low Endotoxin, Azide and BSA Free

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry Panel Builder

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Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
Spillover Popups - Visualize the spectra of individual fluorochromes
Antigen Density Selector - Match fluorochrome brightness with antigen density

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Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Format

Low Endotoxin, Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: CD117/c-kit

CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with it's ligand is critical for the development of hematopoietic stem cells. The 2B8 antibody does not block c-Kit activity.

Long Name

Stem Cell Factor Receptor

Alternate Names

c-kit, CD117, ckit, KIT, PBT, SCF R, SCFR

Gene Symbol

KIT

UniProt

P10721

Additional CD117/c-kit Products

Product Documents for CD117/c-kit Antibody (CDX-0158) - Low Endotoxin, Azide and BSA Free

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Certificate of Analysis

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Product Specific Notices for CD117/c-kit Antibody (CDX-0158) - Low Endotoxin, Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.