Cryptosporidium Parvum Antibody (7631) [Biotin]

Novus Biologicals | Catalog # NB100-65674B

Novus Biologicals

Key Product Details

Species Reactivity

Protozoa

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 Clone # 7631
View all Cryptosporidium Parvum Primary Antibodies »

Product Specifications

Immunogen

Intact oocysts of C.Parvum

Reactivity Notes

Reacts with Protozoan. Mouse reactivity reported in scientific literature (PMID:33128513)

Specificity

NB100-65674 detects the protozoa Cryptosporidium parvum, an obligate intracellular parasite of the phylum Apicomplexa. The genome of C. parvum is one of the smallest among unicellular eukaryotic organisms. C. parvum is one of several species that cause cryptosporidiosis; a disease affecting the intestines of mammals and is spread through the fecal-oral route. The main symptom is self-limiting diarrhea in people with intact immune systems. However, in immunocompromised individuals, such as AIDS patients, infection can cause permanent & life-threatening diarrhea. Cryptosporidiosis is one of the most common waterborne diseases worldwide.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Applications for Cryptosporidium Parvum Antibody (7631) [Biotin]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Cryptosporidium Parvum

Members of the genus Cryptosporidium are parasites of the intestinal tracts of fishes, reptiles, birds, and mammals. It seems that members of this genus do not display a high degree of host specificity, so the number of species in this genus remains a matter of some discussion. Cryptosporidium isolated from humans is now referred to as C. parvum. Cryptosporidium infections have been reported from a variety of wild and domesticated animals. Cryptosporidiosis is now recognized as an important opportunistic infection, especially in immunocompromised hosts. Cryptosporidium is a small protozoan parasite, measuring about 3-5 um. It lives on (or just under) the surface of the cells lining the small intestine, reproduces asexually, and oocysts are passed in the feces. Transmission of the infection occurs via the oocysts. Many human infections have been traced to the contamination of drinking water with oocysts from agricultural "run-off" (i.e., drainage from pastures), so it is considered a zoonosis. The most common symptom of cryptosporidiosis is watery diarrhea; other symptoms include stomach cramps or pain, fever, nausea and vomiting. In persons with healthy immune systems, symptoms usually last about 1 to 2 weeks.

Alternate Names

C. parvum

Additional Cryptosporidium Parvum Products

Product Documents for Cryptosporidium Parvum Antibody (7631) [Biotin]

Certificate of Analysis

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Product Specific Notices for Cryptosporidium Parvum Antibody (7631) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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