DNAM-1/CD226 Antibody (MM0248-1X20) - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-12268

Novus Biologicals
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Block/Neutralize

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MM0248-1X20

Format

Azide and BSA Free
View all DNAM-1/CD226 Primary Antibodies »

Product Specifications

Immunogen

Human recombinant DNAM-1/CD226 (extracellular domain)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for DNAM-1/CD226 Antibody (MM0248-1X20) - Azide and BSA Free

Immunohistochemistry-Paraffin: DNAM-1/CD226 Antibody (MM0248-1X20) - Azide and BSA Free [NBP2-12268]

Immunohistochemistry-Paraffin: DNAM-1/CD226 Antibody (MM0248-1X20) - Azide and BSA Free [NBP2-12268]

Immunohistochemistry-Paraffin: DNAM-1/CD226 Antibody (MM0248-1X20) [NBP2-12268] - 10% Buffer formalin fixed and parffine embedded human placental tissue section (4um) is subjected IHC staining using NBP2-12268. Tissue section was pretreated in citric buffer (ph6.0) with microwave for antige retrieval before IHC is applied.

Applications for DNAM-1/CD226 Antibody (MM0248-1X20) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: DNAM-1/CD226

CD226 is a 65kD type I transmembrane glycoprotein, known as DNAM-1 (DNAX accessory molecule-1), PTA1(platelet and T cell activation antigen 1), or TLiSA1 (T lineage-specific activation antigen 1 antigen). It belongs to immunoglobulin superfamily containing 2 Ig-like domains, is expressed on majority of T lymphocytes, NK cells, monocytes, platelets, and a subset of B cells, activated endothelial cells. DNAM-1 is also expressed on CD8+ (but not CD8-) dendritic cells in mouse model. CD226 is an adhesion molecule involved in CTL and NK cell-mediated cytotoxicity. It has been identified that CD155 (poliovirus receptor, PVR) and CD112 (nectin-2, PRR-2) are CD226 ligands. DX11 antibody is able to inhibit CTL and NK cell-mediated cytotoxicity, and to block T cell cytokine production.

Long Name

DNAX Accessory Molecule 1

Alternate Names

CD226, DNAM1, PTA1, TLiSA1

Gene Symbol

CD226

UniProt

Q15762

Additional DNAM-1/CD226 Products

Product Documents for DNAM-1/CD226 Antibody (MM0248-1X20) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for DNAM-1/CD226 Antibody (MM0248-1X20) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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