EBPC

  ( 2 citations )    
Product Datasheet
Catalog Number:0518
Chemical Name:Ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate
Product Details
Citations (2)
Reviews
Biological Activity
Potent aldose reductase inhibitor. Improves the cytotoxicity of anticancer reagents such as cisplatin (Cat.No. 2251) and doxorubicin (Cat.No. 2252) in HeLa cervical carcinoma cells through an increase in ERK activity.
Technical Data
  • M.Wt:
    261.28
  • Formula:
    C14H15NO4
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    4450-98-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for EBPC include:

2 Citations: Showing 1 - 2
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  1. Comprehensive analysis of prostaglandin metabolic enzyme expression during pregnancy and the characterization of AKR1B1 as a prostaglandin F synthase at the maternal-conceptus interface in pigs.
    Authors: Seo Et al.
    Pharmacol Res Perspect  2014;90:99
  2. The Prostaglandin F Synthase Activity of the Human Aldose Reductase AKR1B1 Brings New Lenses to Look at Pathologic Conditions.
    Authors: Bresson Et al.
    Front Pharmacol  2012;3:98

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