ERO1LB Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-48263

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

ERO1-like beta. (Uniprot# Q86YB8)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ERO1LB Antibody - BSA Free

ERO1LB Antibody - BSA Free

Immunohistochemistry: ERO1LB Antibody - BSA Free [NBP3-48263] -

Immunohistochemistry: ERO1LB Antibody - BSA Free [NBP3-48263] - Immunohistochemistry of paraffin-embedded human pancreas cancer using (ERO1LB antibody) at dilution of 1:50
ERO1LB Antibody - BSA Free

Western Blot: ERO1LB Antibody - BSA Free [NBP3-48263] -

Western Blot: ERO1LB Antibody - BSA Free [NBP3-48263] - HeLa cells were subjected to SDS PAGE followed by western blot with (ERO1LB antibody) at dilution of 1:1000

Applications for ERO1LB Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:500

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ERO1LB

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress

Alternate Names

DKFZp779C1042, DKFZp779I0141, EC 1.8.4, EC 1.8.4.-, Endoplasmic oxidoreductin-1-like protein B, ERO1-L(beta), ERO1-L-beta, ERO1-like beta (S. cerevisiae), ERO1-like protein beta, FLJ11003, oxidoreductin-1-L-beta

Gene Symbol

ERO1B

Additional ERO1LB Products

Product Documents for ERO1LB Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for ERO1LB Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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