ESRP2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76537

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human RBM35B. The immunogen is located within the last 50 amino acids of RBM35B.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (80%)

Specificity

RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least two isoforms of RBM35B are known to exist; this antibody will detect both isoforms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ESRP2 Antibody - BSA Free

Western Blot: ESRP2 AntibodyBSA Free [NBP1-76537]

Western Blot: ESRP2 AntibodyBSA Free [NBP1-76537]

Western Blot: ESRP2 Antibody [NBP1-76537] - Human lung tissue lysate with ESRP2 antibody at 1 ug/mL.
ESRP2 Antibody - BSA Free

Immunohistochemistry: ESRP2 Antibody - BSA Free [NBP1-76537] -

Immunohistochemistry: ESRP2 Antibody - BSA Free [NBP1-76537] - Immunohistochemistry of ESRP2 in human lung tissue with ESRP2 antibody at 5 ug/mL.
ESRP2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: ESRP2 Antibody - BSA Free [NBP1-76537] -

Immunocytochemistry/ Immunofluorescence: ESRP2 Antibody - BSA Free [NBP1-76537] - Immunofluorescence of ESRP2 in human lung tissue cells with ESRP2 antibody at 20 ug/mL.

Applications for ESRP2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ESRP2

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.

Alternate Names

epithelial splicing regulatory protein 2, FLJ21918, FLJ22248, RBM35BRNA-binding protein 35B, RNA binding motif protein 35A, RNA binding motif protein 35B, RNA-binding motif protein 35B

Gene Symbol

ESRP2

Additional ESRP2 Products

Product Documents for ESRP2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for ESRP2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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