Ganaxolone

Catalog # Availability Size / Price Qty
2531/10
2531/50
Ganaxolone | CAS No. 38398-32-2 | GABA-A Receptor Modulators
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Description: Potent positive allosteric modulator of GABAA receptors
Alternative Names: CCD 1042

Chemical Name: (3α,5α)-3-Hydroxy-3-methyl-pregnan-20-one

Product Details
Citations (1)
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Biological Activity

Potent positive allosteric modulator of GABAA receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors (EC50 values are 94, 122 and 213 nM for α2β1γ2L, α3β1γ2L and α1β1γ2L receptors respectively). Exerts anticonvulsive effects in a broad range of animal seizure models.

Technical Data

M.Wt:
332.53
Formula:
C22H36O2
Solubility:
Soluble to 10 mM in DMSO with gentle warming and to 20 mM in ethanol
Storage:
Store at +4°C
CAS No:
38398-32-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Ganaxolone

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