gp130/CD130 Antibody (BLR114H)

Name: gp130/CD130 Antibody (BLR114H)
Brand: Novus Biologicals
SKU: NBP3-14702
Price: 519 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-14702

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR114H

View all gp130 Primary Antibodies »

Product Specifications

Immunogen

residues 23-323 (ECD)

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for gp130/CD130 Antibody (BLR114H)

Western Blot;gp130/CD130 Antibody (BLR114H)[NBP3-14702]

Western Blot;gp130/CD130 Antibody (BLR114H) Whole cell lysate (50 µg) from NCI-H226, MCF-7, IMR-90, Jurkat, HeLa, A-549, Hep-G2, and HEK293T cells prepared using NETN lysis buffer. Antibody: Rabbit anti-GP130/CD130 recombinant monoclonal antibody used at 1:1000. Secondary: HRP-conjugated goat anti-rabbit IgG. Detection: Chemiluminescence with an exposure time of 30 seconds. Lower Panel: Rabbit anti-COPB2.

Applications for gp130/CD130 Antibody (BLR114H)

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Borate Buffered Saline (BBS) pH 8.2 with, BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: gp130

CD130 is encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Long Name

Glycoprotein 130

Alternate Names

CD130, IL6ST

Gene Symbol

IL6ST

Additional gp130 Products

Product Documents for gp130/CD130 Antibody (BLR114H)

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Certificate of Analysis

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Product Specific Notices for gp130/CD130 Antibody (BLR114H)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.