HNF1 Antibody - BSA Free

A: Although we have not tested the cross-reactivity of antibody NBP1-33596 with HNF1B, I have performed a sequence comparison analysis for you, and HNF1A only has 54% homology with HNF1B (56% for isoform B), suggesting that the antibody is unlikely to bind to HNF1B.The website data sheet does state which portion of HNF1 alpha the antibody was raised against, so this information is available for our customers before they begin their experiments. HNF1 alpha was the protein this antibody was generated for, but cross-reactivity against other proteins was not tested. We do not state that the antibody will definitely not bind to HNF1 beta. However, I understand that the datasheet can be misinterpreted. Unfortunately, we are unable to carry out your requests, but we can offer you a refund or replacement. Please let me know how you wish to proceed. I am making enquiries into whether any of our antibodies are known to be specific to either HNF1B or HNF1A, and will let you know as soon as I have an answer. We do have overexpression lysates for HNF1A and HNF1B: NBL-11630 and NBL-11631. Unfortunately, we cannot change the pack size of any of our products. However, we will give you a credit for the cost of the NBP1-33596 antibody, and you can use this to reduce the cost of the products you would like. I may be able to get you a discount on top of this. Unfortunately, none of the HNF1A antibodies have been tested for cross-reactivity to HNF1B, and none of the HNF1B antibodies have been tested for cross-reactivity to HNF1A. Therefore, we do not have any antibodies that I can guarantee are specific to either HNF1A or HNF1B; please accept my apologies. Please could you let me know the PO of your original order with us? Or did you order via a distributor? Also, as I said in my previous email, we do not have an HNF1B antibody that has been tested for cross-reactivity against HNF1A. However, if you would still like one from us, I would recommend NBP1-89680, because the lab have let me know that the antigen of this antibody has 47% sequence identity to the HNF1A gene. This antibody shows nuclear staining of moderate to strong intensity in the gastrointestinal tract, renal tubules, pancreatic ducts and decidual cells; it shows no positivity in hepatocytes. 'Although HNF-1 alpha, but not HNF-1 beta, is expressed in the liver, HNF-1 alpha and HNF-1 beta are coexpressed in the murine Hepa1A cell line and in the mammalian kidney where a subset of hepatocyte genes are expressed', accor