Human 5-HT7 (NP_000863) VersaClone cDNA RDC0251: R&D Systems
Preparation and Storage
  • Stability & Storage
    Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: 5-HT7
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. This isoform (A) is the predominant isoform in spleen, caudate and hippocampus. 5-HT7 isoform B is expressed at lower levels. 5-HT7 belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Pharmacological and genetic tools targeting 5-HT7 in preclinical animal models have implicated this receptor in diverse (patho)physiological processes of the central nervous system (CNS).
  • Long Name:
    5-Hydroxytryptamine Receptor 7
  • Entrez Gene IDs:
    3363 (Human); 15566 (Mouse); 65032 (Rat)
  • Alternate Names:
    5HT7; 5-HT7; 5-HT-7; 5-HT75-hydroxytryptamine receptor 7; 5-HT-X; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); HTR7; serotonin 5-HT-7 receptor; Serotonin receptor 7
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