55 results for "5-HT7" in Products
5-HT7 Products
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. This isoform (A) is the predominant isoform in spleen, caudate and hippocampus. 5-HT7 isoform B is expressed at lower levels. 5-HT7 belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Pharmacological and genetic tools targeting 5-HT7 in preclinical animal models have implicated this receptor in diverse (patho)physiological processes of the central nervous system (CNS).
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Flow, ICC/IF, Simple Western |
![Western Blot: 5-HT7 Antibody [NB100-56352]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Western-Blot-NB100-56352-img0003.jpg "Western Blot: 5-HT7 Antibody [NB100-56352]")
| Reactivity: | Human, Mouse, Rat, Guinea Pig |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP1-46598]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Immunohistochemistry-Paraffin-NBP1-46598-img0002.jpg "Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP1-46598]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #1015322 |
| Applications: | IHC, Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #4E6D2 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: 5-HT7 Antibody (4E6D2) [NBP3-15870]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-4E6D2-Western-Blot-NBP3-15870-img0003.jpg "Western Blot: 5-HT7 Antibody (4E6D2) [NBP3-15870]")
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: 5-HT7 Antibody [NBP1-44051]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Western-Blot-NBP1-44051-img0003.jpg "Western Blot: 5-HT7 Antibody [NBP1-44051]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Immunohistochemistry-Paraffin-NBP3-14527-img0001.jpg "Immunohistochemistry-Paraffin: 5-HT7 Antibody [NBP3-14527]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1954 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry: 5-HT7 Antibody [NBP2-68957]](https://resources.rndsystems.com/images/products/5-HT7-Antibody-Immunohistochemistry-NBP2-68957-img0001.jpg "Immunohistochemistry: 5-HT7 Antibody [NBP2-68957]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: 5-HT7 Overexpression Lysate [NBP2-06701]](https://resources.rndsystems.com/images/products/5HT7-Receptor-Overexpression-Lysate-Native-Western-Blot-NBP2-06701-img0002.jpg "Western Blot: 5-HT7 Overexpression Lysate [NBP2-06701]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Applications: | AC |
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | AP |
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% |
5-HT1 agonist; also has high affinity for 5-ht5a and 5-HT7
| Alternate Names: | AH-21467,5-CT |
| Purity: | ≥99% |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #1015322 |
| Applications: | Flow |
![5-HT7 Antibody (1015322) [Allophycocyanin]](https://resources.rndsystems.com/images/products/fab10325a_mouse-monoclonal-5-ht7-antibody-1015322-allophycocyanin-flow-cytometry-54202412315..jpg "Detection of 5-HT7 in 5-HT7 HEK293/eGFP transfecants vs Irrelevant HEK293/eGFP transfecants by Flow Cytometry")
Potent and selective 5-HT7 antagonist; brain penetrant
| Chemical Name: | (2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine hydrochloride |
| Purity: | ≥98% |
Potent 5-HT7 agonist
| Chemical Name: | (2S)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin |
| Purity: | ≥98% |
High affinity and selective 5-HT7 antagonist; orally bioavailable
| Chemical Name: | 6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride |
| Purity: | ≥98% |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1015322 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1015322 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1015322 |
| Applications: | Flow |