Human CCR3 (NP_001828) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0006
Product Details
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Human CCR3 (NP_001828) VersaClone cDNA Summary

CCR3 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR3 is 355 amino acids (aa) in length with a predicted molecular weight of 41 kDa. Mouse and rat CCR3 share 70% and 68% aa sequence identity with the human protein, respectively. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: CCR3

Entrez Gene IDs
1232 (Human); 12771 (Mouse); 117027 (Rat); 448802 (Canine)
Alternate Names
b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; CCR3; CCR-3; CD193 antigen; CD193; chemokine (C-C motif) receptor 3; CKR3CC-CKR-3CMKBR3CD193; eosinophil CC chemokine receptor 3; Eosinophil eotaxin receptor; MGC102841

Reagents Provided

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Tocris Small Molecules

SB 328437

SB 297006

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Human CCR3 (NP_001828) VersaClone cDNA
By Anonymous on 04/03/2018
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