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Human CFL1 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB11669S Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11669S-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CFL1 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide specific for human CFL1 around aa 30 in Direct ELISA.
Source
Monoclonal Mouse IgG2b Clone # 1093310
Purification
Protein A or G purified
Immunogen
Synthetic Peptide
Accession # P23528
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CFL1

Cofilin-1 (CFL1) is an 18.5 kDa protein that is a member of the actin deploy family (ADF). It is involved in the biological activities of various malignancies, including infiltration, metastasis, and chemotherapy resistance. Overexpression of CFL is associated with aggressive features and poor prognosis in malignancies. CFL1 also plays a crucial role in B cell, T cell infiltration, cytokine and NF-kappa B signaling pathways and can serve as a useful biomarker for diagnosis of inflammatory diseases.  

Long Name
cofilin 1
Entrez Gene IDs
1072 (Human); 12631 (Mouse); 29271 (Rat)
Alternate Names
18 kDa phosphoprotein; CFL; CFL1; cofilin 1 (non-muscle); cofilin; Cofilin, non-muscle isoform; cofilin-1; HEL-S-15; p18

Product Datasheets

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