Human CXCL7/NAP‑2 Biotinylated Antibody
Human CXCL7/NAP‑2 Biotinylated Antibody Summary
Ala59-Asp128
Accession # P02775
Complete Your Research
Complete Your Experiment
Applications
Human CXCL7/NAP-2 Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CXCL7/NAP-2
Neutrophil Activating Peptide 2 (NAP-2), Connective Tissue Activating Protein III (CTAP‑III) and beta -thrombogulin ( beta ‑TG), are proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP) which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELR domain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR2 and to chemoattract and activate neutrophils. Although CTAP-III, beta -TG and PBP represent amino-terminal extended variants of NAP-2 and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. It has been shown that the additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2 and may account for lack of NAP-2 activity.
- Schall, T. (1994) The Cytokine Handbook, 2nd edition, A. Thomson, ed. Academic Press, New York, p. 419.
- Malkowski, M.G. et al. (1997) J. Mol. Biol. 266:367.
Product Datasheets
Citations for Human CXCL7/NAP‑2 Biotinylated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
3
Citations: Showing 1 - 3
Filter your results:
Filter by:
-
Development of a Glycosaminoglycan Derived, Selectin Targeting Anti-Adhesive Coating to Treat Endothelial Cell Dysfunction
Authors: JR Wodicka, AM Chambers, GS Sangha, CJ Goergen, A Panitch
Pharmaceuticals (Basel), 2017;10(2):.
Species: Human
Sample Types: Platelet Rich Plasma (PRP)
Applications: ELISA Development (Detection) -
Up-regulation of platelet activation in hemophilia A.
Authors: van Bladel ER, Roest M
Haematologica, 2011;0(0):.
Species: Human
Sample Types: Plasma
Applications: ELISA Development -
High platelet reactivity is associated with myocardial infarction in premenopausal women: a population-based case-control study.
Authors: Snoep JD, Roest M, Barendrecht AD
J. Thromb. Haemost., 2010;8(5):906-13.
Species: Human
Sample Types: Plasma
Applications: ELISA Development
FAQs
No product specific FAQs exist for this product, however you may
View all Antibody FAQsIsotype Controls
Reconstitution Buffers
Staining Reagents
Supplemental Cell Selection Products
Supplemental ELISA Products
Reviews for Human CXCL7/NAP‑2 Biotinylated Antibody
There are currently no reviews for this product. Be the first to review Human CXCL7/NAP‑2 Biotinylated Antibody and earn rewards!
Have you used Human CXCL7/NAP‑2 Biotinylated Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
