Catalog Number: 3652
Chemical Name: (3α,5β)-3-Hydroxy-pregnan-20-one
Biological Activity
GABAA receptor positive allosteric modulator. Neuroactive steroid.
Technical Data
  • M.Wt:
    318.49
  • Formula:
    C21H34O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Storage:
    Store at RT
  • CAS No:
    128-20-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Structure-activity relationships for steroid interaction with the γ-aminobutyric acidA receptor complex.
    Harrison et al.
    J.Pharmacol.Exp.Ther., 1987;241:346
  2. Differential modulation of the γ-aminobutyric acid type C receptor by neuroactive steroids.
    Morris et al.
    Mol.Pharmacol., 1999;56:752

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