Pregnanolone

Tocris Bioscience | Catalog # 3652

Postitive allosteric modulator of GABAA receptors
Tocris Bioscience

Key Product Details

Description

Postitive allosteric modulator of GABAA receptors
View all GABA-A Receptor Modulators »

Product Description

Pregnanolone is a GABAA receptor positive allosteric modulator. Neuroactive steroid.

Product Specifications for Pregnanolone

Molecular Weight

318.49

Formula

C21H34O2

Storage

Store at RT

Chemical Name

(3α,5β)-3-Hydroxy-pregnan-20-one

CAS Number

128-20-1

PubChem ID

31402

InChI Key

AURFZBICLPNKBZ-YZRLXODZSA-N

SMILES

C[C@@]12[C@@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(C)=O)([H])C[C@H](O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.85 100
Ethanol 31.85 100

Preparing Stock Solutions for Pregnanolone

The following data is based on the product molecular weight 318.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.14 mL 15.70 mL 31.40 mL
5 mM 0.63 mL 3.14 mL 6.28 mL
10 mM 0.31 mL 1.57 mL 3.14 mL
50 mM 0.06 mL 0.31 mL 0.63 mL

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for Pregnanolone

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pregnanolone

For research use only

Related Research Areas

GABA Receptors

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