Human HLA Class I APC-conjugated Antibody
Human HLA Class I APC-conjugated Antibody Summary
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of HLA Class I in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human HLA Class I APC-conjugated Monoclonal Antibody (Catalog # FAB7098A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: HLA Class I
HLA-A, B, and C are approximately 45 kDa transmembrane glycoproteins in the major histocompatibility complex 1 (MHC I) family. They contain three alpha domains in their extracellular regions. HLA molecules are expressed on nearly all nucleated cells in association with the 12 kDa beta 2-Microglobulin. This complex binds peptides derived from pathogenic cytosolic or extracellular proteins such as viral or microbial proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD8+ cytotoxic T cells. The activated cytotoxic T cell then kills the presenting cell. Mismatched MHC I alleles between a host and a donor lead to transplant rejection.
Citation for Human HLA Class I APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1-fluoro-2-(imidazo-[1,2-?]pyridin-3-yl)ethyl-bisphosphonate
Authors: MA Lawson, FH Ebetino, A Mazur, AD Chantry, J Paton-Houg, HR Evans, D Lath, MK Tsoumpra, MW Lundy, RL Dobson, M Quijano, AA Kwaasi, JE Dunford, X Duan, JT Triffitt, G Jeans, RG Russell
J. Bone Miner. Res, 2017-04-21;0(0):.
Sample Types: Whole Cells
Applications: Flow Cytometry
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