Human IFN-alpha Alexa Fluor® 750-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: IFN-alpha

Interferon-alpha (IFN-alpha or IFN-alpha ), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. Many IFN-alpha subtypes exist, IFN-alpha 1 to IFN alpha -21. The major subtypes identified are IFN-alpha 1, IFN-alpha 2, IFN-alpha 8, IFN-alpha 10, IFN-alpha 14 and IFN-alpha 21. MAB93454 detects human IFN-alpha 2a,4a,6,7,8,10,16, and 17 in direct ELISA.

Product Datasheets

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