The classical active IKK complex, composed of IKK alpha, IKK beta, and two forms of processed IKK gamma, phosphorylates and inactivates IkB, resulting in the release and nuclear translocation of active NFkB. The regulatory IKK gamma is required for activation of the IKK complex. IKK epsilon is an IKK-related kinase with 30% structural homology to IKK alpha and beta, and is present in a subset of IKK complexes.
Human IKK beta (NP_001547) VersaClone cDNA
R&D Systems | Catalog # RDC2824
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IKK beta
Long Name
IkB Kinase beta
Alternate Names
IkBKB, IKK2, NFKBIKB
Gene Symbol
IKBKB
UniProt
Additional IKK beta Products
Product Documents for Human IKK beta (NP_001547) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human IKK beta (NP_001547) VersaClone cDNA
For research use only
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Associated Pathways
Notch Signaling Pathways
Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways
Toll-Like Receptor Signaling Pathways