Home / IL-1 beta/IL-1F2 / Human IL-1 beta/IL-1F2 DuoSet ELISA

Human IL-1 beta/IL-1F2 DuoSet ELISA

Catalog #: DY201
294 Citations 30 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
DY201
DY201-05
Ancillary Products Available
DY008B: DuoSet ELISA Ancillary Reagent Kit 2
DY999B: Substrate Reagent Pack
DY999: Substrate Reagent Pack
Human IL-1 beta / IL-1F2 ELISA Standard Curve
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Product Details
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Citations (294)
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Supplemental Products
Reviews (30)
Summary Product Features Kit Content Other Reagents Required Data Examples Product Datasheets Preparation and Storage Background

Human IL-1 beta/IL-1F2 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
3.9 - 250 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human IL-1 beta/IL-1F2. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

 

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Scientific Data

N/A Human IL-1 beta / IL-1F2 ELISA Standard Curve View Larger

Human IL-1 beta / IL-1F2 ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-1 beta/IL-1F2

The Interleukin 1 (IL-1) family of proteins consists of the classic members IL-1 alpha, IL-1 beta, and IL-1ra, plus IL-18, IL-33 and IL-1F5-F10. IL-1 alpha and IL-1 beta bind to the same cell surface receptors and share biological functions. IL-1 is not produced by unstimulated cells of healthy individuals with the exception of skin keratinocytes, some epithelial cells, and certain cells of the central nervous system. However, in response to inflammatory agents, infections, or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cell types is observed. IL-1 beta plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. Inappropriate or prolonged production of IL-1 has been implicated in a variety of pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. 

 IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both are synthesized as 31 kDa precursors that are subsequently cleaved into mature proteins of approximately 17.5 kDa. Cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. Neither IL-1 alpha nor IL-1 beta contains a typical hydrophobic signal peptide, but evidence suggests that these factors can be secreted by non-classical pathways. A portion of unprocessed IL-1 alpha can be presented on the cell membrane and may retain biological activity. The precursor form of IL-1 beta, unlike the IL-1 alpha precursor, shows little or no biological activity in comparison to the processed form. Both unprocessed and mature forms of IL-1 beta are exported from the cell. 
 IL-1 alpha and IL-1 beta exert their effects through immunoglobulin superfamily receptors that additionally bind IL-1ra. The 80 kDa transmembrane type I receptor (IL-1 RI) is expressed on T cells, fibroblasts, keratinocytes, endothelial cells, synovial lining cells, chondrocytes, and hepatocytes. The 68 kDa transmembrane type II receptor (IL-1 RII) is expressed on B cells, neutrophils, and bone marrow cells. The two IL-1 receptor types show approximately 28% homology in their extracellular domains but differ significantly in that the type II receptor has a cytoplasmic domain of only 29 amino acids (aa), whereas the type I receptor has a 213 aa cytoplasmic domain. IL-1 RII does not appear to signal in response to IL-1 and may function as a decoy receptor that attenuates IL-1 function. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction. IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1. Soluble forms of both IL-1 RI and IL-1 RII have been detected in human plasma, synovial fluids, and the conditioned media of several human cell lines. In addition, IL-1 binding proteins that resemble soluble IL-1 RII are encoded by vaccinia and cowpox viruses.

Long Name:
Interleukin 1 beta
Entrez Gene IDs:
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names:
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

 

Citations for Human IL-1 beta/IL-1F2 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

294 Citations: Showing 1 - 10
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  1. Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis
    Authors: M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi
    PLoS ONE, 2023;18(1):e0280385.
    Species: Human
    Sample Types: Cell Culture Supernates
  2. CXCL12 and CXCR4 as Novel Biomarkers in Uric Acid-Induced Inflammation and Patients with Gouty Arthritis
    Authors: SK Kim, JY Choe, KY Park
    Biomedicines, 2023;11(3):.
    Species: Human
    Sample Types: Serum
  3. microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells
    Authors: J Wang, G Li, M Lin, S Lin, L Wu
    BMC molecular and cell biology, 2022;23(1):60.
    Species: Human
    Sample Types: Cell Culture Supernates
  4. A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistance
    Authors: H Chen, ME Diolaiti, PC O'Leary, A Rojc, NJ Krogan, M Kim, A Ashworth
    Molecular Cancer Therapeutics, 2022;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  5. PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical beta-coronavirus disease
    Authors: M Duhalde Ve, D Olivera, G Gastão Dav, M Bertullo, V Noya, G Fabiano de, S Primon Mur, I Castro, AP Arévalo, M Crispo, G Galliussi, S Russo, D Charbonnie, F Rammauro, M Jeldres, C Alamón, V Varela, C Batthyany, M Bollati-Fo, P Oppezzo, O Pritsch, JL Proença-Mó, HI Nakaya, E Trias, L Barbeito, I Anegon, MC Cuturi, P Moraes-Vie, M Segovia, M Hill
    Science Advances, 2022;8(38):eabn6545.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages
    Authors: L Zhu, W Qi, G Yang, Y Yang, Y Wang, L Zheng, Y Fu, X Cheng
    Cells, 2022;11(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  7. Antibacterial and Anti-Inflammatory Effects of Apolipoprotein E
    Authors: M Puthia, JK Marzinek, G Petruk, G Ertürk Ber, PJ Bond, J Petrlova
    Biomedicines, 2022;10(6):.
    Species: Human
    Sample Types: Plasma
  8. Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells
    Authors: M Busch, G Bredeck, F Waag, K Rahimi, H Ramachandr, T Bessel, S Barcikowsk, A Herrmann, A Rossi, RPF Schins
    Biomolecules, 2022;12(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  9. IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
    Authors: L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder
    Cells, 2022;11(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  10. Green and Roasted Coffee Extracts Inhibit Interferon-beta Release in LPS-Stimulated Human Macrophages
    Authors: V Artusa, C Ciaramelli, A D'Aloia, FA Facchini, N Gotri, A Bruno, B Costa, A Palmioli, C Airoldi, F Peri
    Frontiers in Pharmacology, 2022;13(0):806010.
    Species: Human
    Sample Types: Cell Culture Supernates
  11. "HIIT the Inflammation": Comparative Effects of Low-Volume Interval Training and Resistance Exercises on Inflammatory Indices in Obese Metabolic Syndrome Patients Undergoing Caloric Restriction
    Authors: D Reljic, W Dieterich, HJ Herrmann, MF Neurath, Y Zopf
    Nutrients, 2022;14(10):.
    Species: Human
    Sample Types: Serum
  12. Discovery of a novel GRPR antagonist for protection against cisplatin-induced acute kidney injury
    Authors: MJ Yu, C Li, SS Deng, XM Meng, RS Yao
    Bioorganic chemistry, 2022;124(0):105794.
    Species: Human
    Sample Types: Cell Culture Supernates
  13. Cytokine Profile and Anti-Inflammatory Activity of a Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells (PRS CK STORM)
    Authors: JP Lapuente, A Blázquez-M, J Marco-Brua, G Gómez, P Desportes, J Sanz, P Fernández, M García-Gil, F Bermejo, JV San Martín, A Algaba, JC De Gregori, D Lapuente, A De Gregori, B Lapuente, MV Andrés, A Anel
    Biomolecules, 2022;12(4):.
    Species: Human
    Sample Types: Cell Culture Supernates
  14. Immune Modulating Brevetoxins: Monocyte Cytotoxicity, Apoptosis, and Activation of M1/M2 Response Elements Is Dependent on Reactive Groups
    Authors: JR McCall, KT Sausman, DM Keeler, AP Brown, SL Turrise
    Marine Drugs, 2022;20(4):.
    Species: Human
    Sample Types: Cell Culture Supernates
  15. T Lymphocyte Serotonin 5-HT7 Receptor Is Dysregulated in Natalizumab-Treated Multiple Sclerosis Patients
    Authors: F Reverchon, C Guillard, L Mollet, P Auzou, D Gosset, F Madouri, A Valéry, A Menuet, C Ozsancak, M Pallix-Guy, S Morisset-L
    Biomedicines, 2022;10(10):.
    Species: Human
    Sample Types: Plasma
  16. NLRP3 inflammasome triggers interleukin-37 release from human monocytes
    Authors: A Gritsenko, R Díaz-Pino, G Lopez-Cast
    European Journal of Immunology, 2022;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  17. Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation
    Authors: K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi
    Scientific Reports, 2022;12(1):5181.
    Species: Human
    Sample Types: Cell Culture Supernates
  18. Anti-inflammatory role of GM1 and other gangliosides on microglia
    Authors: D Galleguill, Q Wang, N Steinberg, A Zaidi, G Shrivastav, K Dhami, GC Daskhan, EN Schmidt, Z Dworsky-Fr, F Giuliani, M Churchward, C Power, K Todd, A Taylor, MS Macauley, S Sipione
    Journal of Neuroinflammation, 2022;19(1):9.
    Species: Rat
    Sample Types: Cell Culture Supernates
  19. Sulforaphane Reduces Pro-Inflammatory Response To Palmitic Acid In Monocytes And Adipose Tissue Macrophages
    Authors: EJ Williams, L Guillemina, BS Berthon, S Eslick, T Wright, C Karihaloo, M Gately, KJ Baines, LG Wood
    The Journal of nutritional biochemistry, 2022;0(0):108978.
    Species: Human
    Sample Types: Cell Culture Supernates
  20. E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing
    Authors: AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl
    Cells, 2022;11(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site
    Authors: G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown
    Scientific Reports, 2022;12(1):3990.
    Species: Human
    Sample Types: Blister Fluid
  22. Anti-inflammatory effects of an autologous gold-based serum therapy in osteoarthritis patients
    Authors: J Feldt, AJ Donaubauer, J Welss, U Schneider, US Gaipl, F Paulsen
    Scientific Reports, 2022;12(1):3560.
    Species: Human
    Sample Types: Serum
  23. Interleukin-17, a salivary biomarker for COVID-19 severity
    Authors: FS Sharif-Ask, NS Sharif-Ask, S Hafezi, B Mdkhana, HAH Alsayed, AW Ansari, B Mahboub, AM Zakeri, MH Temsah, W Zahir, Q Hamid, R Halwani
    PLoS ONE, 2022;17(9):e0274841.
    Species: Human
    Sample Types: Saliva
  24. Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement
    Authors: C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert
    International Journal of Molecular Sciences, 2022;23(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  25. Signal strength of STING activation determines cytokine plasticity and cell death in human monocytes
    Authors: D Kabelitz, M Zarobkiewi, M Heib, R Serrano, M Kunz, G Chitadze, D Adam, C Peters
    Scientific Reports, 2022;12(1):17827.
    Species: Human
    Sample Types: Cell Culture Supernates
  26. Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death
    Authors: JP Borges, RSR Sætra, A Volchuk, M Bugge, P Devant, B Sporsheim, BR Kilburn, CL Evavold, JC Kagan, NM Goldenberg, TH Flo, BE Steinberg
    Elife, 2022;11(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  27. EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis
    Authors: JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park
    Arthritis Research & Therapy, 2022;24(1):254.
    Species: Human
    Sample Types: Serum
  28. Development of an Electrochemical CCL5 Chemokine Immunoplatform for Rapid Diagnosis of Multiple Sclerosis
    Authors: S Guerrero, E Sánchez-Ti, L Agüí, A González-C, P Yáñez-Sede, JM Pingarrón
    Biosensors, 2022;12(8):.
    Species: Human
    Sample Types: Serum
  29. Anti-inflammatory activities of Coleus forsteri (formerly Plectranthus forsteri) extracts on human macrophages and chemical characterization
    Authors: M Nicolas, M Lasalo, S Chow, C Antheaume, K Huet, E Hnawia, GJ Guillemin, M Nour, M Matsui
    Frontiers in Pharmacology, 2022;13(0):1081310.
    Species: Human
    Sample Types: Cell culture supernate
  30. Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever
    Authors: MSJ Mangan, F Gorki, K Krause, A Heinz, A Pankow, T Ebert, D Jahn, K Hiller, V Hornung, M Maurer, FI Schmidt, R Gerhard, E Latz
    PloS Biology, 2022;20(11):e3001351.
    Species: Human
    Sample Types: Cell Culture Supernates
  31. Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway
    Authors: K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou
    International Journal of Molecular Sciences, 2022;24(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. Distinct changes in endosomal composition promote NLRP3 inflammasome activation
    Authors: Z Zhang, R Venditti, L Ran, Z Liu, K Vivot, A Schürmann, JS Bonifacino, MA De Matteis, R Ricci
    Nature Immunology, 2022;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  33. Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells
    Authors: CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral
    Microbial pathogenesis, 2022;0(0):105881.
    Species: Human
    Sample Types: Cell Culture Supernates
  34. On the Bioactivity of Echinacea purpurea Extracts to Modulate the Production of Inflammatory Mediators
    Authors: SF Vieira, VMF Gonçalves, CP Llaguno, F Macías, ME Tiritan, RL Reis, H Ferreira, NM Neves
    Oncogene, 2022;23(21):.
    Species: Human
    Sample Types: Cell Culture Supernates
  35. Hybrid Mineral/Organic Material Induces Bone Bridging and Bone Volume Augmentation in Rat Calvarial Critical Size Defects
    Authors: M Dubus, L Scomazzon, C Ledouble, J Braux, A Beljebbar, L Van Gulick, A Baldit, C Gorin, H Alem, N Bouland, M Britton, J Schiavi, TJ Vaughan, C Mauprivez, H Kerdjoudj
    Cells, 2022;11(18):.
    Species: Human
    Sample Types: Cell Culture Supernates
  36. Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study
    Authors: LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts
    Cytokine, 2022;162(0):156102.
    Species: Human
    Sample Types: Cell Culture Supernates
  37. ADS024, a Bacillus velezensis strain, protects human colonic epithelial cells against C. difficile toxin-mediated apoptosis
    Authors: Y Xie, A Chupina Es, B Nelson, H Feng, C Pothoulaki, L Chesnel, HW Koon
    Frontiers in Microbiology, 2022;13(0):1072534.
    Species: Human
    Sample Types: Cell Culture Supernates
  38. FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system
    Authors: Y Zhu, H Zhang, H Mao, S Zhong, Y Huang, S Chen, K Yan, Z Zhao, X Hao, Y Zhang, H Yao, X Huang, M Wang, W Zhang, J Li, G Meng, X Qin, Z Ye, J Shen, Y Song, Y Xu, Z Yang, L Wang, Y Zhang, L Wen
    Cell Death and Differentiation, 2022;0(0):.
    Species: Mouse
    Sample Types: Serum
  39. Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS
    Authors: W Dieterich, C Schuster, P Gundel, KA Scherf, D Pronin, S Geisslitz, A Börner, MF Neurath, Y Zopf
    Nutrients, 2022;14(20):.
    Species: Human
    Sample Types: Cell Culture Supernates
  40. Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems
    Authors: LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt
    Scientific Reports, 2022;12(1):12448.
    Species: Human
    Sample Types: Cell Culture Supernates
  41. Phytohustil� and root extract of Althaea officinalis L. exert anti-inflammatory and anti-oxidative properties and improve the migratory capacity of endothelial cells in vitro
    Authors: GA Bonaterra, J Schmitt, K Schneider, H Schwarzbac, H Aziz-Kalbh, O Kelber, J Müller, R Kinscherf
    Frontiers in Pharmacology, 2022;13(0):948248.
    Species: Human
    Sample Types: Cell Culture Supernates
  42. JC2-11, a benzylideneacetophenone derivative, attenuates inflammasome activation
    Authors: G Lee, H Ahn, JH Yun, J Park, E Lee, S Oh, GS Lee
    Scientific Reports, 2022;12(1):22484.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  43. Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling
    Authors: J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li
    International journal of biological sciences, 2022;18(11):4545-4559.
    Species: Human
    Sample Types: Cell Culture Supernates
  44. Alpinetin Suppresses Zika Virus-Induced Interleukin-1beta Production and Secretion in Human Macrophages
    Authors: N Wikan, S Potikanond, P Hankittich, P Thaklaewph, S Monkaew, DR Smith, W Nimlamool
    Pharmaceutics, 2022;14(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  45. SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
    Authors: EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundar, J Aguado, AP Zamora, CLD McMillan, B Liang, NYG Peng, JDJ Sng, FT Saima, JN Fung, JD Lee, D Paramitha, R Parry, MS Avumegah, A Isaacs, MW Lo, Z Miranda-Ch, D Bradshaw, C Salinas-Re, NW Rajapakse, EJ Wolvetang, TP Munro, A Rojas-Fern, PR Young, KJ Stacey, AA Khromykh, KJ Chappell, D Watterson, TM Woodruff
    Molecular Psychiatry, 2022;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  46. The Restorative Effect of Human Amniotic Fluid Stem Cells on Spinal Cord Injury
    Authors: M Lale Ataei, M Karimipour, P Shahabi, R Pashaei-As, E Ebrahimie, M Pashaiasl
    Cells, 2021;10(10):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  47. IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming
    Authors: N Niu, J Yao, RC Bast, AK Sood, J Liu
    Oncogenesis, 2021;10(9):65.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit
    Authors: T Katopodi, S Petanidis, K Domvri, P Zarogoulid, D Anestakis, C Charalampi, D Tsavlis, C Bai, H Huang, L Freitag, W Hohenforst, D Matthaios, K Porpodis
    Scientific Reports, 2021;11(1):15455.
    Species: Human
    Sample Types: Cell Culture Supernates
  49. "Plurethosome" as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation
    Authors: M Sguizzato, F Ferrara, P Mariani, A Pepe, R Cortesi, N Huang, F Simelière, P Boldrini, A Baldissero, G Valacchi, E Esposito
    Pharmaceutics, 2021;13(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  50. Plasma markers in pulmonary hypertension subgroups correlate with patient survival
    Authors: T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars
    Respiratory Research, 2021;22(1):137.
    Species: Human
    Sample Types: Plasma
  51. Polyphenol-rich extract and fractions of Terminalia phaeocarpa Eichler possess hypoglycemic effect, reduce the release of cytokines, and inhibit lipase, &alpha-glucosidase, and &alpha-amilase enzymes
    Authors: JHS Gomes, UC Mbiakop, RL Oliveira, JR Stehmann, RM Pádua, SF Cortes, FC Braga
    Journal of ethnopharmacology, 2021;271(0):113847.
    Species: Human
    Sample Types: Cell Culture Supernates
  52. The influence of the gut microbiome on BCG-induced trained immunity
    Authors: M Stražar, VP Mourits, VACM Koeken, LCJ de Bree, SJCFM Moorlag, LAB Joosten, R van Crevel, H Vlamakis, MG Netea, RJ Xavier
    Genome Biology, 2021;22(1):275.
    Species: Human
    Sample Types: Cell Culture Supernates
  53. Synthetic Material Abdominal Swabs Reduce Activation of Platelets and Leukocytes Compared to Cotton Materials
    Authors: K Gerling, LM Herrmann, C Salewski, M Wolf, P Müllerbade, D Siegel-Axe, HP Wendel, C Schlensak, M Avci-Adali, S Stoppelkam
    Biomolecules, 2021;11(7):.
    Species: Human
    Sample Types: Cell Culture Supernates
  54. IL-1beta augments TGF-beta inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics
    Authors: S Zhang, Y Fan, L Qin, X Fang, C Zhang, J Yue, W Bai, G Wang, Z Chen, H Renz, C Skevaki, X Liu, M Xie
    Respiratory Research, 2021;22(1):216.
    Species: Human
    Sample Types: Sputum
  55. The effect of moderate wine consumption on cytokine secretion by peripheral blood mononuclear cells: A randomized clinical study in coronary heart disease patients
    Authors: E Fragopoulo, C Argyrou, M Detopoulou, S Tsitsou, S Seremeti, M Yannakouli, S Antonopoul, G Kolovou, P Kalogeropo
    Cytokine, 2021;146(0):155629.
    Species: Human
    Sample Types: Cell Culture Supernates
  56. Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
    Authors: N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton
    Nature Communications, 2021;12(1):1209.
    Species: Human
    Sample Types: Cell Culture Supernates
  57. Protein-Bound Uremic Toxins Induce Reactive Oxygen Species-Dependent and Inflammasome-Mediated IL-1beta Production in Kidney Proximal Tubule Cells
    Authors: M Mihajlovic, MM Krebber, Y Yang, S Ahmed, V Lozovanu, D Andreeva, MC Verhaar, R Masereeuw
    Biomedicines, 2021;9(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  58. Differential recognition of HIV-stimulated IL-1&beta and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages
    Authors: K Triantafil, CJK Ward, M Czubala, RG Ferris, E Koppe, C Haffner, V Piguet, VK Patel, H Amrine-Mad, L Modis, SL Masters, M Triantafil
    PloS Pathogens, 2021;17(4):e1009417.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. Timing of Tributyrin Supplementation Differentially Modulates Gastrointestinal Inflammation and Gut Microbial Recolonization Following Murine Ileocecal Resection
    Authors: V Mocanu, H Park, J Dang, N Hotte, A Thiesen, M Laffin, H Wang, D Birch, K Madsen
    Nutrients, 2021;13(6):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  60. IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
    Authors: R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, S Parameswar, C Liang, C Arana, B Zhang, B Wakeland, J Zhou, MT Weirauch, LC Kottyan, EK Wakeland, C Pasare
    Cell Reports, 2021;34(12):108891.
    Species: Human
    Sample Types: Cell Culture Supernates
  61. Itaconate confers tolerance to late NLRP3 inflammasome activation
    Authors: M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov
    Cell Reports, 2021;34(10):108756.
    Species: Human
    Sample Types: Cell Culture Supernates
  62. Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
    Authors: K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner
    Cell Reports, 2021;34(10):108826.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae
    Authors: AD Brunaugh, H Seo, Z Warnken, L Ding, SH Seo, HDC Smyth
    PLoS ONE, 2021;16(2):e0246803.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes
    Authors: P Jitprasert, M Khamphio, P Petsrichua, VGH Eijsink, W Poolsri, C Muanprasat, K Rangnoi, M Yamabhai
    PLoS ONE, 2021;16(2):e0246381.
    Species: Human
    Sample Types: Cell Culture Supernates
  65. Proteopathic tau primes and activates interleukin-1beta via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
    Authors: S Jiang, NM Maphis, J Binder, D Chisholm, L Weston, W Duran, C Peterson, A Zimmerman, MA Mandell, SD Jett, E Bigio, C Geula, N Mellios, JP Weick, GA Rosenberg, E Latz, MT Heneka, K Bhaskar
    Cell Reports, 2021;36(12):109720.
    Species: Human
    Sample Types: Tissue Homogenates
  66. Associations between salivary cytokines and periodontal and microbiological parameters in orthodontic patients
    Authors: Y Chen, WK Wong, JC Seneviratn, S Huang, C McGrath, U Hagg
    Medicine, 2021;100(10):e24924.
    Species: Human
    Sample Types: Saliva
  67. Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response
    Authors: MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad
    Cell Death & Disease, 2021;12(3):241.
    Species: Human
    Sample Types: Cell Culture Supernates
  68. Neutrophil extracellular trap clearance by synovial macrophages in gout
    Authors: JH Jeong, SJ Choi, SM Ahn, JS Oh, YG Kim, CK Lee, B Yoo, S Hong
    Arthritis Research & Therapy, 2021;23(1):88.
    Species: Human
    Sample Types: Cell Culture Supernates
  69. Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells
    Authors: C Panda, C Voelz, P Habib, C Mevissen, T Pufe, C Beyer, S Gupta, A Slowik
    Cells, 2021;10(7):.
    Species: Human
    Sample Types: Cell Culture Supernates
  70. Lipopolysaccharide stimulation test on cultured PBMCs assists the discrimination of cryopyrin-associated periodic syndrome from systemic juvenile idiopathic arthritis
    Authors: CY Wu, WL Fan, YM Chiu, HY Yang, WI Lee, JL Huang
    Scientific Reports, 2021;11(1):11903.
    Species: Human
    Sample Types: Cell Culture Supernates
  71. Interleukin-1&alpha Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation
    Authors: K Bernau, JP Leet, H Floerke, EM Bruhn, AL Noll, IS McDermott, S Esnault, NN Jarjour, N Sandbo
    Cells, 2021;10(3):.
    Species: Human
    Sample Types: BALF
  72. Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production
    Authors: YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang
    Arthritis Research & Therapy, 2021;23(1):171.
    Species: Human
    Sample Types: Cell Culture Supernates
  73. Sintered S53P4 bioactive glass scaffolds have anti-inflammatory properties and stimulate osteogenesis in vitro
    Authors: R Björkenhei, E Jämsen, E Eriksson, P Uppstu, L Aalto-Setä, L Hupa, KK Eklund, M Ainola, NC Lindfors, J Pajarinen
    European cells & materials, 2021;41(0):15-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  74. Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets
    Authors: SH Kim, SH Hong, JH Lee, DH Lee, K Jung, JY Yang, HS Shin, J Lee, J Jeong, JH Oh
    Toxics, 2021;9(3):.
    Species: Human
    Sample Types: cell culture supernatant
  75. An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles
    Authors: M Busch, AAM Kämpfer, RPF Schins
    Chemosphere, 2021;284(0):131345.
    Species: Human
    Sample Types: Cell Culture Supernates
  76. Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis
    Authors: H Bonnekoh, C Vera, A Abad-Perez, S Radetzki, M Neuenschwa, E Specker, NA Mahnke, S Frischbutt, E Latz, M Nazaré, JV Kries, M Maurer, J Scheffel, K Krause
    Clinical and translational allergy, 2021;11(5):e12045.
    Species: Human
    Sample Types: Tissue Homogenates
  77. Structural Deformation of MTX Induced by Nanodrug Conjugation Dictate Intracellular Drug Transport and Drug Efficacy
    Authors: JY Park, JS Hyun, JG Jee, SJ Park, D Khang
    International Journal of Nanomedicine, 2021;16(0):4943-4957.
    Species: Human
    Sample Types: Cell Culture Supernates
  78. Low levels of PCSK9 are associated with remission in patients with rheumatoid arthritis treated with anti-TNF-&alpha: potential underlying mechanisms
    Authors: J Frostegård, S Ahmed, I Hafström, S Ajeganova, M Rahman
    Arthritis Research & Therapy, 2021;23(1):32.
    Species: Human
    Sample Types: Cell Culture Supernates
  79. Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures
    Authors: JW Kennedy, PM Tsimbouri, P Campsie, S Sood, PG Childs, S Reid, PS Young, DRM Meek, CS Goodyear, MJ Dalby
    Scientific Reports, 2021;11(1):22741.
    Species: Human
    Sample Types: Cell Culture Supernates
  80. Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
    Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
    Cell Reports, 2021;36(12):109726.
    Species: Human
    Sample Types: Cell Culture Supernates
  81. COVID-19 Modulates Inflammatory and Renal Markers That May Predict Hospital Outcomes among African American Males
    Authors: W Fonseca, N Asai, K Yagi, CA Malinczak, G Savickas, CC Johnson, S Murray, EM Zoratti, NW Lukacs, J Li, CF Schuler Iv
    Viruses, 2021;13(12):.
    Species: Human
    Sample Types: Whole Blood
  82. A prospective cohort study providing insights for markers of adverse pregnancy outcome in older mothers
    Authors: SC Lean, RL Jones, SA Roberts, AEP Heazell
    BMC pregnancy and childbirth, 2021;21(1):706.
    Species: Human
    Sample Types: Serum
  83. Decreased microRNA-155 in Behcet's disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production
    Authors: L Liang, Q Zhou, L Feng
    Arthritis Research & Therapy, 2021;23(1):135.
    Species: Human
    Sample Types: Cell Culture Supernates
  84. Psychological symptoms and salivary inflammatory biomarkers in patients with dentofacial deformities: a case-control study
    Authors: MCC Volkweis, GW Neculqueo, RDS Freitas, APA Dagnino, GG Fritscher, TQ Irigaray, MM Campos
    Scientific Reports, 2021;11(1):11083.
    Species: Human
    Sample Types: Saliva
  85. Attenuation of High Glucose-Induced Damage in RPE Cells through p38 MAPK Signaling Pathway Inhibition
    Authors: G Maugeri, C Bucolo, F Drago, S Rossi, M Di Rosa, R Imbesi, V D'Agata, S Giunta
    Frontiers in Pharmacology, 2021;12(0):684680.
    Species: Human
    Sample Types: Cell Culture Supernates
  86. Parabens disrupt non-canonical inflammasome activation
    Authors: H Ahn, H Lee, G Lee, J Park, HW Sung, E Lee, GS Lee
    International immunopharmacology, 2021;101(0):108196.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  87. Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis
    Authors: X Zhu, Y Zhan, Y Gu, Q Huang, T Wang, Z Deng, J Xie
    Frontiers in Physiology, 2021;12(0):733650.
    Species: Human
    Sample Types: Cell Culture Supernates
  88. Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled phase 2 trial
    Authors: V Mocanu, Z Zhang, EC Deehan, DH Kao, N Hotte, S Karmali, DW Birch, KK Samarasing, J Walter, KL Madsen
    Nature Medicine, 2021;27(7):1272-1279.
    Species: Human
    Sample Types: Serum
  89. In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei
    Authors: D Reddi, L Durant, D Bernardo, A Noble, NR English, P Hendy, GC Clark, JL Prior, ED Williamson, SC Knight
    Vaccines, 2021;9(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  90. Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner
    Authors: W Zhang, G Yin, H Zhao, H Ling, Z Xie, C Xiao, Y Chen, Y Lin, T Jiang, S Jin, J Wang, X Yang
    Cell Death & Disease, 2021;12(1):102.
    Species: Human
    Sample Types: Serum
  91. Propionibacterium acnes Accelerates Intervertebral Disc Degeneration by Inducing Pyroptosis of Nucleus Pulposus Cells via the ROS-NLRP3 Pathway
    Authors: G Tang, X Han, Z Lin, H Qian, B Chen, C Zhou, Y Chen, W Jiang
    Oxidative Medicine and Cellular Longevity, 2021;2021(0):4657014.
    Species: Human
    Sample Types: Cell Culture Supernates
  92. Differential Regulation of Circulating Soluble Receptor for Advanced Glycation End Products (sRAGEs) and Its Ligands S100A8/A9 Four Weeks Post an Exercise Intervention in a Cohort of Young Army Recruits
    Authors: IA Drosatos, JN Tsoporis, S Izhar, S Gupta, G Tsirebolos, E Sakadakis, AS Triantafyl, A Rigopoulos, D Rigopoulos, LS Rallidis, I Rizos, TG Parker
    Biomolecules, 2021;11(9):.
    Species: Human
    Sample Types: Plasma
  93. Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
    Authors: MC Kiritsy, K McCann, D Mott, SM Holland, SM Behar, CM Sassetti, AJ Olive
    Elife, 2021;10(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  94. The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection
    Authors: QT Phan, J Lin, NV Solis, M Eng, M Swidergall, F Wang, S Li, SL Gaffen, TF Chou, SG Filler
    MBio, 2021;0(0):e0271621.
    Species: Human
    Sample Types: Cell Culture Supernates
  95. Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages
    Authors: X Ding, H Kambara, R Guo, A Kanneganti, M Acosta-Zal, J Li, F Liu, T Bei, W Qi, X Xie, W Han, N Liu, C Zhang, X Zhang, H Yu, L Zhao, F Ma, JR Köhler, HR Luo
    Nature Communications, 2021;12(1):6699.
    Species: Human
    Sample Types: Cell Culture Supernates
  96. Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis
    Authors: S Schlichtne, NH Meyer, IM Yasinska, N Aliu, SM Berger, BF Gibbs, E Fasler-Kan, VV Sumbayev
    International immunopharmacology, 2021;100(0):108155.
    Species: Human
    Sample Types: Cell Culture Supernates
  97. Skin Substitute Preparation Method Induces Immunomodulatory Changes in Co-Incubated Cells through Collagen Modification
    Authors: J Holl, C Pawlukiani, J Corton Rui, D Groth, K Grubczak, HR Hady, J Dadan, J Reszec, S Czaban, C Kowalewski, M Moniuszko, A Eljaszewic
    Pharmaceutics, 2021;13(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  98. Inflammatory responses to metal oxide ceramic nanopowders
    Authors: S Jamieson, A Mawdesley, D Deehan, J Kirby, J Holland, A Tyson-Capp
    Scientific Reports, 2021;11(1):10531.
    Species: Human
    Sample Types: Cell Culture Supernates
  99. HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
    Authors: L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang
    Autophagy, 2021;0(0):1-20.
    Species: Rat
    Sample Types: Serum
  100. A new cytokine-based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia
    Authors: P Peterlin, J Gaschet, T Guillaume, A Garnier, M Eveillard, A Le Bourgeo, M Cherel, C Debord, Y Le Bris, O Theisen, C Godon, B Mahé, V Dubruille, S Wuilleme, C Touzeau, T Gastinne, N Blin, A Lok, B Tessoulin, S Le Gouill, P Moreau, MC Béné, P Chevallier
    Cancer Medicine, 2020;0(0):.
    Species: Human
    Sample Types: Serum
  101. Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells
    Authors: V Panagiotak, D Ivanyuk, S De Cicco, W Haq, A Arsi?, C Yu, D Messelodi, M Oldrati, DC Schöndorf, MJ Perez, RP Cassatella, M Jakobi, N Schneiderh, T Gasser, I Niki?-Spie, M Deleidi
    Nat Commun, 2020;11(1):5163.
    Species: Human
    Sample Types: Whole Cells
  102. Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles
    Authors: C Pavan, R Santalucia, R Leinardi, M Fabbiani, Y Yakoub, F Uwambayine, P Ugliengo, M Tomatis, G Martra, F Turci, D Lison, B Fubini
    Proc Natl Acad Sci U S A, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  103. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
    Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
    PLoS Pathog., 2020;16(8):e1008781.
    Species: Human
    Sample Types: Cell Culture Supernates
  104. The non-saponin fraction of Korean Red Ginseng (KGC05P0) decreases glucose uptake and transport in�vitro and modulates glucose production via down-regulation of the PI3K/AKT pathway in�vivo
    Authors: SJ Park, D Lee, D Kim, M Lee, G In, ST Han, SW Kim, MH Lee, OK Kim, J Lee
    J Ginseng Res, 2020;44(2):362-372.
    Species: Human
    Sample Types: Serum
  105. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease
    Authors: X Zhang, R Wang, D Hu, X Sun, H Fujioka, K Lundberg, ER Chan, Q Wang, R Xu, ME Flanagan, AA Pieper, X Qi
    Science Advances, 2020;6(49):.
    Species: Human
    Sample Types: Cell Culture Supernates
  106. An observational study of innate immune responses in patients with acute appendicitis
    Authors: T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens
    Sci Rep, 2020;10(1):17352.
    Species: Human
    Sample Types: Cell Culture Supernates
  107. Amyloid Beta Peptide (A&beta1-42) Reverses the Cholinergic Control of Monocytic IL-1&beta Release
    Authors: K Richter, R Ogiemwonyi, S Wilker, AI Chaveiro, A Agné, M Hecker, M Reichert, AL Amati, KD Schlüter, I Manzini, G Schmalzing, JM McIntosh, W Padberg, V Grau, A Hecker
    J Clin Med, 2020;9(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  108. Vibration synergistically enhances IL-1&beta and TNF-&alpha in compressed human periodontal ligament cells in the frequency-dependent manner
    Authors: S Benjakul, B Unat, P Thammanich, C Leethanaku
    J Oral Biol Craniofac Res, 2020;10(4):412-416.
    Species: Human
    Sample Types: Cell Culture Supernates
  109. Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21
    Authors: L Mercurio, D Lulli, F Mascia, E Dellambra, C Scarponi, M Morelli, C Valente, ML Carbone, S Pallotta, G Girolomoni, C Albanesi, S Pastore, S Madonna
    Aging (Albany NY), 2020;12(8):6823-6851.
    Species: Human
    Sample Types: Cell Culture Supernates
  110. Cerebrospinal fluid of chronic osteoarthritic patients induced interleukin-6 release in human glial cell-line T98G
    Authors: W Liu, C Li, FCK Tan, HJ Neo, YH Chan, CM Low, TL Lee
    BMC Anesthesiol, 2020;20(1):69.
    Species: Human
    Sample Types: Cell Culture Supernates
  111. Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids
    Authors: MJ Pérez, D Ivanyuk, V Panagiotak, G Di Napoli, S Kalb, D Brunetti, R Al-Shaana, SA Kaeser, SA Fraschka, M Jucker, M Zeviani, C Viscomi, M Deleidi
    Mol. Psychiatry, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Lysates
  112. Reprogramming of profibrotic macrophages for treatment of bleomycin-induced pulmonary fibrosis
    Authors: F Zhang, EA Ayaub, B Wang, E Puchulu-Ca, YH Li, SU Hettiarach, SD Lindeman, Q Luo, S Rout, M Srinivasar, A Cox, K Tsoyi, C Nickerson-, IO Rosas, PS Low
    EMBO Mol Med, 2020;0(0):e12034.
    Species: Human
    Sample Types: Cell Culture Supernates
  113. MG53 suppresses interferon-&beta and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
    Authors: M Sermershei, AD Kenney, PH Lin, TM McMichael, C Cai, K Gumpper, TMA Adesanya, H Li, X Zhou, KH Park, JS Yount, J Ma
    Nat Commun, 2020;11(1):3624.
    Species: Human
    Sample Types: Cell Culture Supernates
  114. Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
    Authors: P Ruscitti, P Di Benedet, O Berardicur, N Panzera, N Grazia, AR Lizzi, P Cipriani, Y Shoenfeld, R Giacomelli
    Sci Rep, 2020;10(1):12232.
    Species: Human
    Sample Types: Cell Culture Supernates
  115. Cigarette smoke and extracellular Hsp70 induce secretion of ATP and differential activation of NLRP3 inflammasome in monocytic and bronchial epithelial cells
    Authors: L Rumora, A Somborac-B, I Hlap?i?, A Hulina-Tom, MG Rajkovi?
    Cytokine, 2020;135(0):155220.
    Species: Human
    Sample Types: Cell Culture Supernates
  116. NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells
    Authors: VM Abrahams, Z Tang, G Mor, S Guller
    J Reprod Immunol, 2020;142(0):103214.
    Species: Human
    Sample Types: Cell Culture Supernates
  117. Differentially Expressed Genes of Natural Killer Cells Can Distinguish Rheumatoid Arthritis Patients from Healthy Controls
    Authors: NM Elemam, MY Hachim, S Hannawi, AA Maghazachi
    Genes (Basel), 2020;11(5):.
    Species: Human
    Sample Types: Plasma
  118. PB1-F2 protein of highly pathogenic influenza A (H7N9) virus selectively suppresses RNA-induced NLRP3 inflammasome activation through inhibition of MAVS-NLRP3 interaction
    Authors: PH Cheung, ZW Ye, TT Lee, H Chen, CP Chan, DY Jin
    J. Leukoc. Biol., 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  119. Activation of Human &gamma&delta T Cells: Modulation by Toll-Like Receptor 8 Ligands and Role of Monocytes
    Authors: R Serrano, D Wesch, D Kabelitz
    Cells, 2020;9(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  120. N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
    Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
    Nat Commun, 2020;11(1):2212.
    Species: Human
    Sample Types: Cell Culture Supernates
  121. Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes
    Authors: M De, A Bhushan, S Chinnaswam
    J Leukoc Biol, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  122. Sex Differences in Proatherogenic Cytokine Levels
    Authors: S Bernardi, B Toffoli, F Tonon, M Francica, E Campagnolo, T Ferretti, S Comar, F Giudici, E Stenner, B Fabris
    Int J Mol Sci, 2020;21(11):.
    Species: Human
    Sample Types:
  123. Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma
    Authors: Z Zhai, JM Samson, T Yamauchi, PK Vaddi, Y Matsumoto, CA Dinarello, D Ravindran, M Fujita
    Cancers (Basel), 2020;12(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  124. Modified citrus pectins by UV/H2O2 oxidation at acidic and basic conditions: Structures and in vitro anti-inflammatory, anti-proliferative activities
    Authors: J Cao, J Yang, Z Wang, M Lu, K Yue
    Carbohydr Polym, 2020;247(0):116742.
    Species: Human
    Sample Types: Cell Culture Supernates
  125. Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages
    Authors: LJ Williams, SG Tristram, GR Zosky
    International Journal of Environmental Research and Public Health, 2020;18(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  126. BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils
    Authors: SJCFM Moorlag, YA Rodriguez-, J Gillard, S Fanucchi, K Theunissen, B Novakovic, CM de Bont, Y Negishi, ET Fok, L Kalafati, P Verginis, VP Mourits, VACM Koeken, LCJ de Bree, GJM Pruijn, C Fenwick, R van Crevel, LAB Joosten, I Joosten, H Koenen, MM Mhlanga, DA Diavatopou, T Chavakis, MG Netea
    Cell Rep, 2020;33(7):108387.
    Species: Human
    Sample Types: Cell Culture Supernates
  127. Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion
    Authors: M Estermann, YL Huang, D Septiadi, D Ritz, CY Liang, F Jacob, B Drasler, A Petri-Fink, V Heinzelman, B Rothen-Rut
    PLoS ONE, 2020;15(12):e0241500.
    Species: Human
    Sample Types: Abdominal Fluid
  128. Clinical Response to the CD95-Ligand Inhibitor Asunercept Is Defined by a Pro-Inflammatory Serum Cytokine Profile
    Authors: A Radujkovic, T Boch, F Nolte, D Nowak, C Kunz, A Gieffers, C Müller-Tid, P Dreger, WK Hofmann, T Luft
    Cancers, 2020;12(12):.
    Species: Human
    Sample Types: Serum
  129. Oral Lactobacillus strains reduce cytotoxicity and cytokine release from peripheral blood mononuclear cells exposed to Aggregatibacter actinomycetemcomitans subtypes in vitro
    Authors: N Pahumunto, A Basic, AK Östberg, R Teanpaisan, G Dahlen
    BMC Microbiol., 2020;20(1):279.
    Species: Human
    Sample Types: Cell Culture Supernates
  130. Pancreatic cancer-derived small extracellular vesical Ezrin regulates macrophage polarization and promotes metastasis
    Authors: YT Chang, HY Peng, CM Hu, SC Huang, SC Tien, YM Jeng
    Am J Cancer Res, 2020;10(1):12-37.
    Species: Human
    Sample Types: Cell Culture Supernates
  131. Protective effect of bromfenac sodium on femtosecond laser?assisted cataract surgery via modulating cyclooxygenase?2 expression
    Authors: L Lu, J Zhao, J Wang, Y Qin, J Zhang
    Mol Med Rep, 2020;22(3):2433-2441.
    Species: Human
    Sample Types: Cell Culture Supernates
  132. Who Is Afraid of CRP? Elevated Preoperative CRP Levels Might Attenuate the Increase in Inflammatory Parameters in Response to Lung Cancer Surgery
    Authors: MM Meyer, L Brandenbur, H Hudel, A Agné, W Padberg, A Erdogan, H Nef, AL Amati, O Dörr, B Witte, V Grau
    J Clin Med, 2020;9(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  133. Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
    Authors: PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz
    Cell Rep, 2020;33(2):108247.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  134. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
    Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
    PLoS Pathog., 2020;16(8):e1008781.
    Species: Human
    Sample Types: Cell Culture Supernates
  135. Vibration synergistically enhances IL-1beta and TNF-alpha in compressed human periodontal ligament cells in the frequency-dependent manner
    Authors: S Benjakul, B Unat, P Thammanich, C Leethanaku
    J Oral Biol Craniofac Res, 2020;10(4):412-416.
    Species: Human
    Sample Types: Cell Culture Supernates
  136. Scrodentoids H and I, a Pair of Natural Epimerides from Scrophularia dentata, Inhibit Inflammation through JNK-STAT3 Axis in THP-1 Cells
    Authors: G Mao, L Sun, J Xu, Y Li, C Dunzhu, L Zhang, F Qian
    Evid Based Complement Alternat Med, 2020;2020(0):1842347.
    Species: Human
    Sample Types: Cell Culture Supernates
  137. Salivary Biomarkers of Oral Inflammation Are Associated With Cardiovascular Events and Death Among Kidney Transplant Patients
    Authors: F Ortiz, KM Nylund, H Ruokonen, JH Meurman, J Furuholm, N Bostanci, T Sorsa
    Transplant. Proc., 2020;0(0):.
    Species: Human
    Sample Types: Saliva
  138. Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-kappaB and PI3K-Akt signaling networks
    Authors: MA Haque, I Jantan, H Harikrishn, W Ahmad
    BMC Complement Med Ther, 2020;20(1):245.
    Species: Human
    Sample Types: Cell Culture Supernates
  139. SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
    Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
    medRxiv : the preprint server for health sciences, 2020;0(0):.
    Species: Human
    Sample Types: Fecal Supernates
  140. Modified citrus pectins by UV/H2O2 oxidation at acidic and basic conditions: Structures and in vitro anti-inflammatory, anti-proliferative activities
    Authors: J Cao, J Yang, Z Wang, M Lu, K Yue
    Carbohydr Polym, 2020;247(0):116742.
    Species: Human
    Sample Types: Cell Culture Supernates
  141. Modeling HIV-1 neuropathogenesis using three-dimensional human brain organoids (hBORGs) with HIV-1 infected microglia
    Authors: RS Dos Reis, S Sant, H Keeney, MCE Wagner, V Ayyavoo
    Scientific Reports, 2020;10(1):15209.
    Species: Human
    Sample Types: Organoid
  142. ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes
    Authors: S Niklander, D Bandaru, DW Lambert, KD Hunter
    FEBS Open Bio, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  143. Recombinant Alkaline Phosphatase Prevents Acute on Chronic Liver Failure
    Authors: C Engelmann, D Adebayo, M Oria, F De Chiara, S Novelli, A Habtesion, N Davies, F Andreola, R Jalan
    Sci Rep, 2020;10(1):389.
    Species: Human
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  144. Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16
    Authors: M Ma, CM Percopo, DE Sturdevant, AC Sek, HD Komarow, HF Rosenberg
    J. Immunol., 2019;0(0):.
    Species: Human
    Sample Types: Cell Lysates
  145. Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
    Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2019;60(14):4820-4829.
    Species: Human
    Sample Types: Cell Culture Supernates
  146. EASIX for prediction of survival in lower-risk myelodysplastic syndromes
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    Blood Cancer J, 2019;9(11):85.
    Species: Human
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  147. Physiologic intestinal 18F-FDG uptake is associated with alteration of gut microbiota and proinflammatory cytokine levels in breast cancer
    Authors: HJ Yoon, HN Kim, JI Bang, W Lim, BI Moon, NS Paik, BS Kim, HL Kim
    Sci Rep, 2019;9(1):18273.
    Species: Human
    Sample Types: Serum
  148. Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis
    Authors: L Su, P Pan, P Yan, Y Long, X Zhou, X Wang, R Zhou, B Wen, L Xie, D Liu
    Sci Rep, 2019;9(1):5747.
    Species: Human
    Sample Types: Cell Culture Supernates
  149. Phenotypic and functional stability of leukocytes from human peripheral blood samples: considerations for the design of immunological studies
    Authors: A Navas, L Giraldo-Pa, MD Prieto, J Cabrera, MA Gómez
    BMC Immunol., 2019;20(1):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  150. Cervical cancer-instructed stromal fibroblasts enhance IL-23 expression in dendritic cells to support expansion of Th17 cells
    Authors: B Walch-Rück, R Ströder, L Theobald, J Pahne-Zepp, S Hegde, YJ Kim, RM Bohle, I Juhasz-Bös, EF Solomayer, S Smola
    Cancer Res., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  151. Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells
    Authors: R Saga, K Hasegawa, K Murata, M Chiba, T Nakamura, K Okumura, E Tsuruga, Y Hosokawa
    Oncol Lett, 2019;17(3):3555-3561.
    Species: Human
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  152. In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists
    Authors: R Gramlich, E Aliahmadi, M Peiser
    Int J Mol Sci, 2019;20(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  153. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential
    Authors: D Raghunatha, PM Radford, C Gell, D Negus, C Moore, R Till, PJ Tighe, SP Wheatley, L Martinez-P, RE Sockett, J Tyson
    Sci Rep, 2019;9(1):4293.
    Species: Human
    Sample Types: Cell Culture Supernates
  154. Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans
    Authors: E Kaasinen, O Kuismin, K Rajamäki, H Ristolaine, M Aavikko, J Kondelin, S Saarinen, DG Berta, R Katainen, EAM Hirvonen, A Karhu, A Taira, T Tanskanen, A Alkodsi, M Taipale, E Morgunova, K Franssila, R Lehtonen, M Mäkinen, K Aittomäki, A Palotie, MI Kurki, O Pietiläine, M Hilpert, E Saarentaus, J Niinimäki, J Junttila, K Kaikkonen, P Vahteristo, RC Skoda, MRJ Seppänen, KK Eklund, J Taipale, O Kilpivaara, LA Aaltonen
    Nat Commun, 2019;10(1):1252.
    Species: Human
    Sample Types: Cell Culture Supernates
  155. The effect of compressive force combined with mechanical vibration on human alveolar bone osteoblasts
    Authors: C Chatmahamo, A Pravithara, S Suttapreya, C Leethanaku
    J Oral Biol Craniofac Res, 2019;9(1):81-85.
    Species: Human
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  156. Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
    Authors: C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong
    Mol. Cancer, 2019;18(1):64.
    Species: Human
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  157. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
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    PLoS Pathog., 2019;15(4):e1007689.
    Species: Human
    Sample Types: Cell Culture Supernates
  158. Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages
    Authors: PJ Goddard, J Sanchez-Ga, SL Slater, M Kalyan, D Ruano-Gall, O Marchès, LÁ Fernández, G Frankel, AR Shenoy
    Cell Rep, 2019;27(4):1008-1017.e6.
    Species: Human
    Sample Types: Cell Culture Supernates
  159. Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages
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    PLoS ONE, 2019;14(5):e0217005.
    Species: Human
    Sample Types: Cell Culture Supernates
  160. Inflammasome-Driven Interleukin-1α and�Interleukin-1? Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity
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    JACC Basic Transl Sci, 2019;4(3):304-317.
    Species: Human
    Sample Types: Tissue Culture Supernates
  161. Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
    Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
    MBio, 2019;10(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  162. β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
    Authors: JC Dos Santos, AM Barroso de, MV Teodoro Si, B Cirovic, LCJ de Bree, MSMA Damen, SJCFM Moorlag, RS Gomes, MM Helsen, M Oosting, ST Keating, A Schlitzer, MG Netea, F Ribeiro-Di, LAB Joosten
    Cell Rep, 2019;28(10):2659-2672.e6.
    Species: Human
    Sample Types: Cell Culture Supernates
  163. Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation
    Authors: MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, AF McGettrick, CE Sutton, C Diskin, M Rooke, S Takahashi, S Sundararaj, MG Casarotto, JE Dahlstrom, EM Palsson-Mc, SC Corr, KHG Mills, RJS Preston, N Neamati, Y Xie, JB Baell, PG Board, LAJ O'Neill
    Cell Rep, 2019;29(1):151-161.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
  164. Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
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    BMC Sports Sci Med Rehabil, 2019;11(0):23.
    Species: Human
    Sample Types: Saliva
  165. IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin
    Authors: I Tsilioni, AB Patel, H Pantazopou, S Berretta, P Conti, SE Leeman, TC Theoharide
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Human
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  166. Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
    Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
    Nat Microbiol, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  167. Vaccine antigens modulate the innate response of monocytes to Al(OH)3
    Authors: S Kooijman, J Brummelman, CACM van Els, F Marino, AJR Heck, E van Riet, B Metz, GFA Kersten, JLA Pennings, HD Meiring
    PLoS ONE, 2018;13(5):e0197885.
    Species: Human
    Sample Types: Cell Culture Supernates
  168. Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
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    Arthritis Res. Ther., 2018;20(1):164.
    Species: Human
    Sample Types: Serum
  169. Annexin A1, FPR2/ALX, and inflammatory cytokine expression in peritoneal endometriosis
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    J. Reprod. Immunol., 2018;129(0):30-35.
    Species: Human
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  170. CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
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    Oncol Lett, 2018;15(6):9075-9080.
    Species: Human
    Sample Types: Cell Culture Supernates
  171. TET-2 up-regulation is associated with the anti-inflammatory action of Vicenin-2
    Authors: N Hassan, A Ali, C Withycombe, M Ahluwalia, RH Al-Nasseri, A Tonks, K Morris
    Cytokine, 2018;108(0):37-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  172. Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus
    Authors: L Laencina, V Dubois, V Le Moigne, A Viljoen, L Majlessi, J Pritchard, A Bernut, L Piel, AL Roux, JL Gaillard, B Lombard, D Loew, EJ Rubin, R Brosch, L Kremer, JL Herrmann, F Girard-Mis
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    Species: Human
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  173. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
    Authors: B Lagrange, S Benaoudia, P Wallet, F Magnotti, A Provost, F Michal, A Martin, F Di Lorenzo, BF Py, A Molinaro, T Henry
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    Species: Human
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  174. The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models
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    Int J Mol Sci, 2018;19(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  175. Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism
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    Nat Commun, 2018;9(1):4186.
    Species: Human
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  176. Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
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  177. Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
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    Invest. Ophthalmol. Vis. Sci., 2018;59(2):1158-1166.
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  178. TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
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    Eur Cell Mater, 2018;35(0):13-24.
  179. Analysis of the association between Fc receptor family gene polymorphisms and ocular Beh�et's disease in Han Chinese
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    Sci Rep, 2018;8(1):4850.
    Species: Human
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  180. Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma
    Authors: T Kubo, M Tsujiwaki, Y Hirohashi, T Tsukahara, T Kanaseki, M Nakatsugaw, T Hasegawa, T Torigoe
    Lab. Invest., 2018;0(0):.
    Species: Human
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  181. GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
    Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
    Nat Commun, 2018;9(1):3686.
    Species: Human
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  182. The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1? by Human Cytomegalovirus through Inhibition of NF-kB Activity
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    Viruses, 2018;10(10):.
    Species: Human
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  183. Clinical predictors of liver fibrosis in patients with chronic hepatitis B virus infection from children to adults
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    J. Infect. Dis., 2018;0(0):.
    Species: Human
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  184. A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
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    Nat Commun, 2018;9(1):4630.
    Species: Human
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  185. A central role for P2X7 receptors in human microglia
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    J Neuroinflammation, 2018;15(1):325.
    Species: Human
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  186. Combining Calcium Phosphates with Polysaccharides: A Bone-Inspired Material Modulating Monocyte/Macrophage Early Inflammatory Response
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  187. Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease
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    Br J Ophthalmol, 2018;0(0):.
    Species: Human
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  188. Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface
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    Environ. Pollut., 2018;0(0):.
    Species: Human
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  189. Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages
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    Arterioscler. Thromb. Vasc. Biol., 2018;0(0):.
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  190. A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
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    Cell Rep, 2018;25(13):3706-3720.e8.
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  192. Sulphamethazine derivatives as immunomodulating agents: New therapeutic strategies for inflammatory diseases
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    PLoS ONE, 2018;13(12):e0208933.
    Species: Human
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  193. Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages
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    Virulence, 2018;0(0):1-32.
    Species: Human
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  194. S100B regulates inflammatory response during osteoarthritis via fibroblast growth factor receptor 1 signaling
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    Mol Med Rep, 2018;18(6):4855-4864.
    Species: Human
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  195. Elevated CRP levels predict poor outcome and tumor recurrence in patients with thymic epithelial tumors: A pro- and retrospective analysis
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    Sample Types: Serum
  196. In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens
    Authors: N Goli?, K Veljovi?, N Popovi?, J Djoki?, I Strahini?, I Mrvaljevi?, A Terzi?-Vid
    BMC Microbiol., 2017;17(1):108.
    Species: Human
    Sample Types: Cell Culture Supernates
  197. Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
    Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
    Immun Ageing, 2017;14(0):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  198. Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response
    Authors: S Das, M Raundhal, J Chen, TB Oriss, R Huff, JV Williams, A Ray, P Ray
    JCI Insight, 2017;2(17):.
    Species: Human
    Sample Types: Cell Culture Supernates
  199. Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF-? and IL-1? in third molar surgery: a triple-blind, randomized, placebo-controlled study
    Authors: AFM Albuquerqu, CSR Fonteles, DR do Val, HV Chaves, MM Bezerra, KMA Pereira, PG de Barros, BB de Lima, ECS Soares, TR Ribeiro, FWG Costa
    Int J Oral Maxillofac Surg, 2017;0(0):.
    Species: Human
    Sample Types: Tissue Homogenates
  200. Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation
    Authors: S Zwicker, E Hattinger, D Bureik, A Batycka-Ba, A Schmidt, PA Gerber, S Rothenfuss, M Gilliet, T Ruzicka, R Wolf
    PLoS ONE, 2017;12(4):e0175153.
    Species: Human
    Sample Types: Cell Culture Supernates
  201. Rheumatoid arthritis bone marrow environment supports Th17 response.
    Authors: Ewa Kuca-Warna, Weronika Kurowska, Monika Prochorec, Anna Radzikows, Tomasz Burakowsk, Urszula Skalska, Magdalena Massalska, Magdalena Pleba?czy, Barbara Ma?dyk-No, Iwona S?owi?ska, Robert Gasik, W?odzimierz Ma?li?ski
    Arthritis Research & Therapy, 2017;0(0):1478-6362.
    Species: Human
    Sample Types: Plasma
  202. Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
    Authors: L Chen, MS Eapen, GR Zosky
    Sci Rep, 2017;7(0):45172.
    Species: Human
    Sample Types: Cell Culture Supernates
  203. Iron nanomedicines induce Toll-like receptor activation, cytokine production and complement activation
    Authors: Johan J F Verhoef
    Biomaterials, 2017;119(0):68-77.
    Species: Human
    Sample Types: Cell Culture Supernates
  204. An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition
    Authors: HL Young, EJ Rowling, M Bugatti, E Giurisato, N Luheshi, I Arozarena, JC Acosta, J Kamarashev, DT Frederick, ZA Cooper, A Reuben, J Gil, KT Flaherty, JA Wargo, W Vermi, MP Smith, C Wellbrock, A Hurlstone
    J. Exp. Med., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  205. Altered distribution of peripheral blood dendritic cell subsets in patients with pulmonary paracoccidioidomycosis
    Authors: J Venturini, RS Cavalcante, DV Moris, M de Assis G, AD Levorato, KH Dos Reis, MSP de Arruda, RP Mendes
    Acta Trop., 2017;0(0):.
    Species: Human
    Sample Types: Serum
  206. Induction of immune gene expression and inflammatory mediator release by commonly used surgical suture materials: an experimental in vitro study
    Authors: AM Lock, R Gao, D Naot, B Coleman, J Cornish, DS Musson
    Patient Saf Surg, 2017;11(0):16.
    Species: Human
    Sample Types: Cell Culture Supernates
  207. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
    Authors: SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G N£¤ez, SL Masters, JM Murphy, K Schroder, DL Vaux, KE Lawlor, LM Lindqvist, JE Vince
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  208. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study
    Authors: J Vandooren, S Knoops, JL Aldinucci, L Boon, E Martens, G Opdenakker, E Kolaczkows
    PLoS ONE, 2017;12(4):e0174853.
    Species: Human
    Sample Types: Cell Culture Supernates
  209. Rheumatoid arthritis bone marrow environment supports Th17 response
    Authors: E Kuca-Warna, W Kurowska, M Prochorec-, A Radzikowsk, T Burakowski, U Skalska, M Massalska, M Pleba?czyk, B Ma?dyk-Now, I S?owi?ska, R Gasik, W Ma?li?ski
    Arthritis Res. Ther., 2017;19(1):274.
    Species: Human
    Sample Types: Plasma
  210. Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
    Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
    Sci Rep, 2017;7(1):1815.
    Species: Human
    Sample Types: Cell Culture Supernates
  211. TB lymphadenitis is associated with enhanced baseline and antigen - specific induction of Type 1 and Type 17 cytokines and reduced IL-1? and IL-18 at the site of infection
    Authors: GR Kathamuthu, K Moideen, D Baskaran, VV Banurekha, D Nair, G Sekar, R Sridhar, B Vidyajayan, G Gajendrara, DK Parandhama, A Srinivasan, S Babu
    Clin. Vaccine Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  212. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface
    Authors: LM Scott, AH Bryant, A Rees, B Down, RH Jones, CA Thornton
    Cytokine, 2017;0(0):.
    Species: Human
    Sample Types: Tissue Culture Supernates
  213. Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT
    Authors: S Dabo, P Maillard, M Collados R, MD Hansen, S Mazouz, DJ Bigot, M Tible, G Janvier, O Helynck, P Cassonnet, Y Jacob, J Bellalou, A Gatignol, RC Patel, J Hugon, H Munier-Leh, EF Meurs
    Sci Rep, 2017;7(1):16129.
    Species: Human
    Sample Types: Cell Culture Supernates
  214. IL-18 associated with lung lymphoid aggregates drives IFN? production in severe COPD
    Authors: E Briend, GJ Ferguson, M Mori, G Damera, K Stephenson, NA Karp, S Sethi, CK Ward, MA Sleeman, JS Erjefält, DK Finch
    Respir. Res., 2017;18(1):159.
    Species: Human
    Sample Types: Cell Culture Supernates
  215. In vitro effects of hyaluronic acid on human periodontal ligament cells
    Authors: M Fujioka-Ko, HD Mller, A Mueller, A Lussi, A Sculean, PR Schmidlin, RJ Miron
    BMC Oral Health, 2017;17(1):44.
    Species: Human
    Sample Types: Cell Culture Supernates
  216. Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?
    Aging Cell, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  217. Reduced systemic and mycobacterial antigen-stimulated concentrations of IL-1? and IL-18 in tuberculous lymphadenitis
    Cytokine, 2016;90(0):66-72.
    Species: Human
    Sample Types: Cell Culture Supernates
  218. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
    Sci Rep, 2016;6(0):39035.
    Species: Human
    Sample Types: Cell Culture Supernates
  219. Dental Calculus Stimulates Interleukin-1? Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes
    Authors: JL Montenegro, A Yoshimura, Z Sm, T Kaneko, Y Ozaki, T Ukai, T Miyazaki, E Latz, Y Hara
    PLoS ONE, 2016;11(9):e0162865.
    Species: Human
    Sample Types: Cell Culture Supernates
  220. Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
    Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
    J Leukoc Biol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  221. Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1? and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  222. Receptor-Type Protein-Tyrosine Phosphatase ? and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1
    PLoS ONE, 2016;11(11):e0167324.
    Species: Human
    Sample Types: Cell Culture Supernates
  223. The Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes.
    Authors: Simanski M, Rademacher F, Schroder L, Glaser R, Harder J
    PLoS ONE, 2016;11(1):e0147118.
    Species: Human
    Sample Types: Cell Culture Supernates
  224. Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
    Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
    PLoS ONE, 2016;11(4):e0153118.
    Species: Human
    Sample Types: Cell Culture Supernates
  225. Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide
    Sci Rep, 2016;6(0):36575.
    Species: Human
    Sample Types: Cell Culture Supernates
  226. Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
    Authors: Avery D Posey
    Immunity, 2016;44(6):1444-54.
    Species: Human
    Sample Types: Cell Culture Supernates
  227. Interleukin-17A Induces IL-1? Secretion From RPE Cells Via the NLRP3 Inflammasome
    Authors: S Zhang, N Yu, R Zhang, S Zhang, J Wu
    Invest. Ophthalmol. Vis. Sci, 2016;57(2):312-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  228. CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection
    PLoS Pathog, 2016;12(7):e1005770.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  229. Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
    PLoS Pathog, 2016;12(9):e1005871.
    Species: Human
    Sample Types: Cell Culture Supernates
  230. Combined exposure of diesel exhaust particles and respirable Soufri�re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
    Authors: Ines Tomašek
    Part Fibre Toxicol, 2016;13(1):67.
    Species: Human
    Sample Types: Cell Culture Supernates
  231. 17-oxo-DHA displays additive anti-inflammatory effects with fluticasone propionate and inhibits the NLRP3 inflammasome
    Sci Rep, 2016;6(0):37625.
    Species: Human
    Sample Types: Cell Culture Supernates
  232. Silk-based blood stabilization for diagnostics
    Proc Natl Acad Sci USA, 2016;113(21):5892-7.
    Species: Human
    Sample Types: Serum
  233. Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease
    Sci Rep, 2016;6(0):26662.
    Species: Human
    Sample Types: Cell Culture Supernates
  234. Graphene-augmented nanofiber scaffolds demonstrate new features in cells behaviour
    Sci Rep, 2016;6(0):30150.
    Species: Human
    Sample Types: Cell Culture Supernates
  235. Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
    Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
    Sci Rep, 2016;6(0):24974.
    Species: Human
    Sample Types: Cell Culture Supernates
  236. Biocompatibility of primers and an adhesive used for implant-retained maxillofacial prostheses: An in�vitro analysis
    Authors: Daniela Micheline Dos Santos
    J Prosthet Dent, 2016;0(0):.
  237. Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion
    Authors: Mélissa Noack
    Arthritis Res Ther, 2016;18(0):148.
    Species: Human
    Sample Types: Cell Culture Supernates
  238. DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  239. Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1beta, IFN-beta, and IL-15 Pathways.
    Authors: Mattiola I, Pesant M, Tentorio P, Molgora M, Marcenaro E, Lugli E, Locati M, Mavilio D
    J Immunol, 2015;195(6):2818-28.
    Species: Human
    Sample Types: Cell Culture Supernates
  240. In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
    Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
    Reprod Biol Endocrinol, 2015;13(0):115.
    Species: Human
    Sample Types: Cell Culture Supernates
  241. Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
    Authors: Karmakar M, Katsnelson M, Malak H, Greene N, Howell S, Hise A, Camilli A, Kadioglu A, Dubyak G, Pearlman E
    J Immunol, 2015;194(4):1763-75.
    Species: Human
    Sample Types: Cell Culture Supernates
  242. Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.
    Authors: Antonopoulos C, Russo H, El Sanadi C, Martin B, Li X, Kaiser W, Mocarski E, Dubyak G
    J Biol Chem, 2015;290(33):20167-84.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  243. LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease.
    Authors: Broekman M, Roelofs H, Hoentjen F, Wiegertjes R, Stoel N, Joosten L, de Jong D, Wanten G
    PLoS ONE, 2015;10(7):e0133932.
    Species: Human
    Sample Types: Plasma
  244. Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter.
    Authors: Brand O, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson A, Hill A, Jablons D, Wolters P, Lou J, Marks J, Baron J, Nishimura S
    J Biol Chem, 2015;290(23):14717-28.
    Species: Human
    Sample Types: Tissue Homogenates
  245. SRSF1 facilitates cytosolic DNA-induced production of type I interferons recognized by RIG-I.
    Authors: Xue F, Li X, Zhao X, Wang L, Liu M, Shi R, Zheng J
    PLoS ONE, 2015;10(2):e0115354.
    Species: Human
    Sample Types: Cell Culture Supernates
  246. Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women.
    Authors: McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K
    PLoS ONE, 2015;10(8):e0134619.
    Species: Human
    Sample Types: Plasma
  247. Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.
    Authors: Schupp J, Binder H, Jager B, Cillis G, Zissel G, Muller-Quernheim J, Prasse A
    PLoS ONE, 2015;10(1):e0116775.
    Species: Human
    Sample Types: BALF
  248. The effect of size on Ag nanosphere toxicity in macrophage cell models and lung epithelial cell lines is dependent on particle dissolution.
    Authors: Hamilton, Raymond, Buckingham, Sarah, Holian, Andrij
    Int J Mol Sci, 2014;15(4):6815-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  249. Integrin alphaDbeta2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.
    Authors: Miyazaki Y, Vieira-de-Abreu A, Harris E, Shah A, Weyrich A, Castro-Faria-Neto H, Zimmerman G
    PLoS ONE, 2014;9(11):e112770.
    Species: Human
    Sample Types: Cell Culture Supernates
  250. TLR ligands stimulation protects MSC from NK killing.
    Authors: Giuliani M, Bennaceur-Griscelli A, Nanbakhsh A, Oudrhiri N, Chouaib S, Azzarone B, Durrbach A, Lataillade J
    Stem Cells, 2014;32(1):290-300.
    Species: Human
    Sample Types: Cell Culture Supernates
  251. A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
    Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
    PLoS ONE, 2014;9(5):e96943.
    Species: Human
    Sample Types: Cell Culture Supernates
  252. The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.
    Authors: Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F
    J Biol Chem, 2014;289(3):1364-76.
  253. Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells.
    Authors: Schwarz H, Schmittner M, Duschl A, Horejs-Hoeck J
    PLoS ONE, 2014;9(12):e113840.
    Species: Human
    Sample Types: Cell Culture Supernates
  254. Kineret(R)/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection.
    Authors: Labrousse D, Perret M, Hayez D, da Silva S, Badiou C, Couzon F, Bes M, Chavanet P, Lina G, Vandenesch F, Croisier-Bertin D, Henry T
    PLoS ONE, 2014;9(6):e97546.
  255. Activin A as a mediator of NK-dendritic cell functional interactions.
    Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
    J Immunol, 2014;192(3):1241-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  256. Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
    Authors: Zughaier, Susu M, Kandler, Justin L, Shafer, William
    PLoS ONE, 2014;9(1):e87688.
    Species: Human
    Sample Types: Cell Culture Supernates
  257. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
    Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
    J Biol Chem, 2014;289(27):19231-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  258. Angiopoietin-1 upregulates de novo expression of IL-1beta and Il1-Ra, and the exclusive release of Il1-Ra from human neutrophils.
    Authors: Haddad L, Sirois M
    PLoS ONE, 2014;9(2):e88980.
    Species: Human
    Sample Types: Cell Lysates
  259. Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population.
    Authors: Fang J, Hu R, Hou S, Ye Z, Xiang Q, Qi J, Zhou Y, Kijlstra A, Yang P
    Invest Ophthalmol Vis Sci, 2013;54(13):8384-92.
    Species: Human
    Sample Types: Cell Culture Supernates
  260. Inflammasome induction in Rasmussen's encephalitis: cortical and associated white matter pathogenesis.
    Authors: Ramaswamy V, Walsh J, Sinclair D, Johnson E, Tang-Wai R, Wheatley B, Branton W, Maingat F, Snyder T, Gross D, Power C
    J Neuroinflammation, 2013;10(0):152.
    Species: Human
    Sample Types: Cell Culture Supernates
  261. Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
    Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
    PLoS ONE, 2013;8(12):e82734.
    Species: Human
    Sample Types: Cell Culture Supernates
  262. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
    Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
    Cytokine, 2013;65(2):222-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  263. S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
    Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
    PLoS ONE, 2013;8(4):e62372.
  264. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
    Authors: Suh HS, Choi N, Tarassishin L, Lee SC
    PLoS ONE, 2012;7(4):e35115.
    Species: Human
    Sample Types: Cell Culture Supernates
  265. Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
    Eur J Clin Nutr, 2012;66(9):1072-4.
    Species: Human
    Sample Types: Serum
  266. Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.
    J. Exp. Med., 2012;209(8):1505-17.
    Species: Human
    Sample Types: Cell Culture Supernates
  267. Monocytic microparticles activate endothelial cells in an IL-1{beta}-dependent manner.
    Authors: Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N
    Blood, 2011;118(8):2366-74.
    Species: Human
    Sample Types: Cell Lysates
  268. Interleukin (IL)-31 induces pro-inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins.
    Authors: Kasraie S, Niebuhr M, Werfel T
    Allergy, 2010;65(6):712-21.
    Species: Human
    Sample Types: Cell Culture Supernates
  269. Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
    Authors: van de Veerdonk FL, Smeekens SP, Joosten LA, Kullberg BJ, Dinarello CA, Van der Meer JW, Netea MG
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3030-3.
    Species: Human
    Sample Types: Cell Culture Supernates
  270. Maternal IL-1beta production prevents lung injury in a mouse model of bronchopulmonary dysplasia.
    Authors: Backstrom E, Lappalainen U, Bry K
    Am. J. Respir. Cell Mol. Biol., 2010;42(2):149-60.
    Species: Human
    Sample Types: Tissue Homogenates
  271. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
    Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
    Eur. J. Immunol., 2009;39(5):1221-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  272. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009;119(10):1424-32.
    Species: Human
    Sample Types: Plasma
  273. Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia.
    Authors: Lukkarinen H, Hogmalm A, Lappalainen U, Bry K
    Am. J. Respir. Cell Mol. Biol., 2009;41(1):59-68.
    Species: Human
    Sample Types: Tissue Homogenates
  274. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages.
    Authors: Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H
    Eur. J. Immunol., 2009;39(3):820-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  275. Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
    Authors: Correale J, Farez M
    J. Immunol., 2009;183(9):5999-6012.
    Species: Human
    Sample Types: Cell Culture Supernates
  276. Divergent effects of hypoxia on dendritic cell functions.
    Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A
    Blood, 2008;112(9):3723-34.
    Species: Human
    Sample Types: Cell Culture Supernates
  277. Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
    Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
    J. Cell. Physiol., 2008;214(1):27-37.
    Species: Human
    Sample Types: Cell Culture Supernates
  278. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
    Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
    J. Biol. Chem., 2007;282(44):31882-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  279. Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors.
    Authors: Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H
    Cytokine, 2007;34(5):278-83.
    Species: Human
    Sample Types: Serum
  280. Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis.
    Authors: Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C
    J. Immunol., 2007;179(10):7166-75.
    Species: Human
    Sample Types: Urine
  281. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
    Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
    J. Clin. Invest., 2007;117(12):3664-3672.
    Species: Human
    Sample Types: Cell Culture Supernates
  282. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.
    Authors: Duluc D, Delneste Y, Tan F, Moles MP, Grimaud L, Lenoir J, Preisser L, Anegon I, Catala L, Ifrah N, Descamps P, Gamelin E, Gascan H, Hebbar M, Jeannin P
    Blood, 2007;110(13):4319-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  283. Sepsis and pathophysiology of anthrax in a nonhuman primate model.
    Authors: Stearns-Kurosawa DJ, Lupu F, Taylor FB, Kinasewitz G, Kurosawa S
    Am. J. Pathol., 2006;169(2):433-44.
    Species: Primate - Papio cynocephalus (Yellow Baboon)
    Sample Types: Plasma
  284. Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
    Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
    J. Pharmacol. Exp. Ther., 2006;318(2):741-50.
    Species: Human
    Sample Types: Cell Culture Supernates
  285. Increased ENA-78 in the follicular fluid of patients with endometriosis.
    Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
    Acta Obstet Gynecol Scand, 2006;85(3):336-42.
    Species: Human
    Sample Types: Follicular Fluid
  286. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease.
    Authors: Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA
    Am. J. Pathol., 2006;169(3):987-98.
    Species: Human
    Sample Types: Tissue Homogenates
  287. Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing.
    Authors: Anderson ST, Williams AJ, Brown JR, Newton SM, Simsova M, Nicol MP, Sebo P, Levin M, Wilkinson RJ, Wilkinson KA
    Am. J. Respir. Crit. Care Med., 2006;173(9):1038-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  288. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
    Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
    Eur. J. Immunol., 2005;35(8):2459-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  289. Adherence influences monocyte responsiveness to interleukin-10.
    Authors: Petit-Bertron AF, Fitting C, Cavaillon JM, Adib-Conquy M
    J. Leukoc. Biol., 2003;73(1):145-54.
    Species: Human
    Sample Types: Cell Culture Supernates
  290. Differential effect of serotonin on cytokine production in lipopolysaccharide-stimulated human peripheral blood mononuclear cells: involvement of 5-hydroxytryptamine2A receptors.
    Authors: Cloez-Tayarani I, Petit-Bertron AF, Venters HD, Cavaillon JM
    Int. Immunol., 2003;15(2):233-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  291. Comparison of inflammatory elements in nasal lavage and induced sputum following occupational exposure to moldy-building microbes.
    Authors: Purokivi M, Hirvonen MR, Roponen M, Randell J, Vahteristo M, Tukiainen H
    Inhal Toxicol, 2002;14(6):653-62.
    Species: Human
    Sample Types: Sputum
  292. The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
    Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
    Hum. Reprod., 2002;17(4):1039-45.
    Species: Human
    Sample Types: Peritoneal Fluid
  293. IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions.
    Authors: Cheong YC, Shelton JB, Laird SM, Richmond M, Kudesia G, Li TC, Ledger WL
    Hum. Reprod., 2002;17(1):69-75.
    Species: Human
    Sample Types: Peritoneal Fluid
  294. Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders.
    Authors: Roponen M, Kiviranta J, Seuri M, Tukiainen H, Myllykangas-Luosujarvi R, Hirvonen MR
    Eur. Respir. J., 2001;18(3):542-8.
    Species: Human
    Sample Types: Serum

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Reviews for Human IL-1 beta/IL-1F2 DuoSet ELISA

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Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/13/2023
Sample Tested: Serum-free Cell Culture Supernates

Supernatants of HLF cells exposed to LPS for 6-hrs

Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 01/10/2023
Sample Tested: Cell Lysates
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/16/2022
Sample Tested: Peripheral blood mononuclear cells (PBMCs),plama
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 06/20/2022
Sample Tested: Serum-free Cell Culture Supernates
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/29/2021
Sample Tested: Colon cancer tissue
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 06/25/2021
Sample Tested: Human cell conditioned medium
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/12/2021
Sample Tested: Cell culture supernatant
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/01/2021
Sample Tested: THP-1 human acute monocytic leukemia cell line

THP-1 cells were incubated with 0.1-10ug/ml PAM3CSK4 for 24-hours and culture supernatant was collected. IL-1b standard was fit to a sigmoidal 4-paramater logistic curve. Max IL-1b production was found at the 1ug/ml dosage.

Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By krys bojanowski on 12/09/2020
Sample Tested: Reconstituted Human Ciliated Airway

3D ciliated airway tissues (cat.# 502-3D-24) were from Cell Applications (San Diego, CA) and were cultured in maintenance medium (cat.# 511M-3D-100, Cell Applications).
Twenty four hours after pre-incubation with test substances, tissues were exposed to 1µg/ml endotoxin LPS and IL-1b was was quantified after 48 additional hours. Worked very well.

Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Robert Berahovich on 09/29/2020
Sample Tested: Tissue Culture Media

Detection of IL-1b secreted by human CAR-T cells engineered to express IL-1b (PMC658), compared to normal CAR-T cells (PMC650).

Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 08/11/2020
Sample Tested: Serum and Plasma
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/11/2020
Sample Tested: K562 human chronic myelogenous leukemia cell line
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Evan Williams on 01/15/2020
Sample Tested: Cell culture supernatant
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/14/2019
Sample Tested: MICROGLIA CELLS
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/14/2019
Sample Tested: Microglia cells
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Fiachra Humphries on 09/11/2019
Sample Tested: human PBMC
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Kim Berman on 07/02/2019
Sample Tested: Cell culture supernatant

Not compatible with all substrates.

Human IL-1 beta/IL-1F2 DuoSet ELISA
By Ivan Luzardo on 01/03/2019
Sample Tested: Cell Lysates
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 11/26/2018
Sample Tested: Plasma
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 10/07/2018
Sample Tested: EDTA Plasma
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Kim Han on 07/03/2018
Sample Tested: THP-1 human acute monocytic leukemia cell line
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/12/2018
Sample Tested: Cell culture supernatant
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Leslie Priddy on 03/30/2018
Sample Tested: Serum
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/27/2018
Sample Tested: 7TD1 mouse hybridoma cell line,Human Whole Blood
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/06/2018
Sample Tested: Bone marrow-derived dendritic cells
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 01/25/2018
Sample Tested: THP-1 human acute monocytic leukemia cell line
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 10/17/2017
Sample Tested: U937 human histiocytic lymphoma cell line
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/08/2017
Sample Tested: activated mouse CD8 T cell
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/03/2017
Sample Tested: Human serum
Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate
By Anonymous on 04/04/2016
Sample Tested: THP-1 human acute monocytic leukemia cell line,Various primary cells