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Human IL-1 beta/IL-1F2 DuoSet ELISA

DY201 183 Citations 25 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
DY201
DY201-05
Ancillary Products Available
DY008: DuoSet ELISA Ancillary Reagent Kit 2
Human IL-1 beta / IL-1F2 ELISA Standard Curve
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Citations (183)
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Reviews (25)
Summary Product Features Kit Content Other Reagents Required Data Examples Product Datasheets Preparation and Storage Background

Human IL-1 beta/IL-1F2 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
3.9 - 250 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human IL-1 beta/IL-1F2. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

 

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Data Example

Human IL-1 beta / IL-1F2 ELISA Standard Curve View Larger

Human IL-1 beta / IL-1F2 ELISA Standard Curve

Product Datasheets

Product Datasheet
COA
SDS

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-1 beta/IL-1F2

The Interleukin 1 (IL-1) family of proteins consists of the classic members IL-1 alpha, IL-1 beta, and IL-1ra, plus IL-18, IL-33 and IL-1F5-F10. IL-1 alpha and IL-1 beta bind to the same cell surface receptors and share biological functions. IL-1 is not produced by unstimulated cells of healthy individuals with the exception of skin keratinocytes, some epithelial cells, and certain cells of the central nervous system. However, in response to inflammatory agents, infections, or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cell types is observed. IL-1 beta plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. Inappropriate or prolonged production of IL-1 has been implicated in a variety of pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. 

 IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both are synthesized as 31 kDa precursors that are subsequently cleaved into mature proteins of approximately 17.5 kDa. Cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. Neither IL-1 alpha nor IL-1 beta contains a typical hydrophobic signal peptide, but evidence suggests that these factors can be secreted by non-classical pathways. A portion of unprocessed IL-1 alpha can be presented on the cell membrane and may retain biological activity. The precursor form of IL-1 beta, unlike the IL-1 alpha precursor, shows little or no biological activity in comparison to the processed form. Both unprocessed and mature forms of IL-1 beta are exported from the cell. 
 IL-1 alpha and IL-1 beta exert their effects through immunoglobulin superfamily receptors that additionally bind IL-1ra. The 80 kDa transmembrane type I receptor (IL-1 RI) is expressed on T cells, fibroblasts, keratinocytes, endothelial cells, synovial lining cells, chondrocytes, and hepatocytes. The 68 kDa transmembrane type II receptor (IL-1 RII) is expressed on B cells, neutrophils, and bone marrow cells. The two IL-1 receptor types show approximately 28% homology in their extracellular domains but differ significantly in that the type II receptor has a cytoplasmic domain of only 29 amino acids (aa), whereas the type I receptor has a 213 aa cytoplasmic domain. IL-1 RII does not appear to signal in response to IL-1 and may function as a decoy receptor that attenuates IL-1 function. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction. IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1. Soluble forms of both IL-1 RI and IL-1 RII have been detected in human plasma, synovial fluids, and the conditioned media of several human cell lines. In addition, IL-1 binding proteins that resemble soluble IL-1 RII are encoded by vaccinia and cowpox viruses.

Long Name:
Interleukin 1 beta
Entrez Gene IDs:
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names:
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

 

Citations for Human IL-1 beta/IL-1F2 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

183 Citations: Showing 1 - 10
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  1. Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes
    Authors: P Jitprasert, M Khamphio, P Petsrichua, VGH Eijsink, W Poolsri, C Muanprasat, K Rangnoi, M Yamabhai
    PLoS ONE, 2021;16(2):e0246381.
    Species: Human
    Sample Types: Cell Culture Supernates
  2. Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae
    Authors: AD Brunaugh, H Seo, Z Warnken, L Ding, SH Seo, HDC Smyth
    PLoS ONE, 2021;16(2):e0246803.
    Species: Human
    Sample Types: Cell Culture Supernates
  3. Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
    Authors: K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner
    Cell Reports, 2021;34(10):108826.
    Species: Human
    Sample Types: Cell Culture Supernates
  4. Itaconate confers tolerance to late NLRP3 inflammasome activation
    Authors: M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov
    Cell Reports, 2021;34(10):108756.
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Cigarette smoke and extracellular Hsp70 induce secretion of ATP and differential activation of NLRP3 inflammasome in monocytic and bronchial epithelial cells
    Authors: L Rumora, A Somborac-B, I Hlap?i?, A Hulina-Tom, MG Rajkovi?
    Cytokine, 2020;135(0):155220.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. The non-saponin fraction of Korean Red Ginseng (KGC05P0) decreases glucose uptake and transport in�vitro and modulates glucose production via down-regulation of the PI3K/AKT pathway in�vivo
    Authors: SJ Park, D Lee, D Kim, M Lee, G In, ST Han, SW Kim, MH Lee, OK Kim, J Lee
    J Ginseng Res, 2020;44(2):362-372.
    Species: Human
    Sample Types: Serum
  7. Cerebrospinal fluid of chronic osteoarthritic patients induced interleukin-6 release in human glial cell-line T98G
    Authors: W Liu, C Li, FCK Tan, HJ Neo, YH Chan, CM Low, TL Lee
    BMC Anesthesiol, 2020;20(1):69.
    Species: Human
    Sample Types: Cell Culture Supernates
  8. Reprogramming of profibrotic macrophages for treatment of bleomycin-induced pulmonary fibrosis
    Authors: F Zhang, EA Ayaub, B Wang, E Puchulu-Ca, YH Li, SU Hettiarach, SD Lindeman, Q Luo, S Rout, M Srinivasar, A Cox, K Tsoyi, C Nickerson-, IO Rosas, PS Low
    EMBO Mol Med, 2020;0(0):e12034.
    Species: Human
    Sample Types: Cell Culture Supernates
  9. MG53 suppresses interferon-&beta and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
    Authors: M Sermershei, AD Kenney, PH Lin, TM McMichael, C Cai, K Gumpper, TMA Adesanya, H Li, X Zhou, KH Park, JS Yount, J Ma
    Nat Commun, 2020;11(1):3624.
    Species: Human
    Sample Types: Cell Culture Supernates
  10. Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
    Authors: P Ruscitti, P Di Benedet, O Berardicur, N Panzera, N Grazia, AR Lizzi, P Cipriani, Y Shoenfeld, R Giacomelli
    Sci Rep, 2020;10(1):12232.
    Species: Human
    Sample Types: Cell Culture Supernates
  11. N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
    Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
    Nat Commun, 2020;11(1):2212.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Activation of Human &gamma&delta T Cells: Modulation by Toll-Like Receptor 8 Ligands and Role of Monocytes
    Authors: R Serrano, D Wesch, D Kabelitz
    Cells, 2020;9(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  13. A new cytokine-based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia
    Authors: P Peterlin, J Gaschet, T Guillaume, A Garnier, M Eveillard, A Le Bourgeo, M Cherel, C Debord, Y Le Bris, O Theisen, C Godon, B Mahé, V Dubruille, S Wuilleme, C Touzeau, T Gastinne, N Blin, A Lok, B Tessoulin, S Le Gouill, P Moreau, MC Béné, P Chevallier
    Cancer Medicine, 2020;0(0):.
    Species: Human
    Sample Types: Serum
  14. Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21
    Authors: L Mercurio, D Lulli, F Mascia, E Dellambra, C Scarponi, M Morelli, C Valente, ML Carbone, S Pallotta, G Girolomoni, C Albanesi, S Pastore, S Madonna
    Aging (Albany NY), 2020;12(8):6823-6851.
    Species: Human
    Sample Types: Cell Culture Supernates
  15. PB1-F2 protein of highly pathogenic influenza A (H7N9) virus selectively suppresses RNA-induced NLRP3 inflammasome activation through inhibition of MAVS-NLRP3 interaction
    Authors: PH Cheung, ZW Ye, TT Lee, H Chen, CP Chan, DY Jin
    J. Leukoc. Biol., 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  16. Differentially Expressed Genes of Natural Killer Cells Can Distinguish Rheumatoid Arthritis Patients from Healthy Controls
    Authors: NM Elemam, MY Hachim, S Hannawi, AA Maghazachi
    Genes (Basel), 2020;11(5):.
    Species: Human
    Sample Types: Plasma
  17. Recombinant Alkaline Phosphatase Prevents Acute on Chronic Liver Failure
    Authors: C Engelmann, D Adebayo, M Oria, F De Chiara, S Novelli, A Habtesion, N Davies, F Andreola, R Jalan
    Sci Rep, 2020;10(1):389.
    Species: Human
    Sample Types: Cell Culture Supernates
  18. Vibration synergistically enhances IL-1&beta and TNF-&alpha in compressed human periodontal ligament cells in the frequency-dependent manner
    Authors: S Benjakul, B Unat, P Thammanich, C Leethanaku
    J Oral Biol Craniofac Res, 2020;10(4):412-416.
    Species: Human
    Sample Types: Cell Culture Supernates
  19. Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids
    Authors: MJ Pérez, D Ivanyuk, V Panagiotak, G Di Napoli, S Kalb, D Brunetti, R Al-Shaana, SA Kaeser, SA Fraschka, M Jucker, M Zeviani, C Viscomi, M Deleidi
    Mol. Psychiatry, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Lysates
  20. Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles
    Authors: C Pavan, R Santalucia, R Leinardi, M Fabbiani, Y Yakoub, F Uwambayine, P Ugliengo, M Tomatis, G Martra, F Turci, D Lison, B Fubini
    Proc Natl Acad Sci U S A, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma
    Authors: Z Zhai, JM Samson, T Yamauchi, PK Vaddi, Y Matsumoto, CA Dinarello, D Ravindran, M Fujita
    Cancers (Basel), 2020;12(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  22. SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
    Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
    medRxiv : the preprint server for health sciences, 2020;0(0):.
    Species: Human
    Sample Types: Fecal Supernates
  23. Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
    Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
    PLoS Pathog., 2020;16(8):e1008781.
    Species: Human
    Sample Types: Cell Culture Supernates
  24. Modeling HIV-1 neuropathogenesis using three-dimensional human brain organoids (hBORGs) with HIV-1 infected microglia
    Authors: RS Dos Reis, S Sant, H Keeney, MCE Wagner, V Ayyavoo
    Scientific Reports, 2020;10(1):15209.
    Species: Human
    Sample Types: Organoid
  25. ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes
    Authors: S Niklander, D Bandaru, DW Lambert, KD Hunter
    FEBS Open Bio, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  26. Who Is Afraid of CRP? Elevated Preoperative CRP Levels Might Attenuate the Increase in Inflammatory Parameters in Response to Lung Cancer Surgery
    Authors: MM Meyer, L Brandenbur, H Hudel, A Agné, W Padberg, A Erdogan, H Nef, AL Amati, O Dörr, B Witte, V Grau
    J Clin Med, 2020;9(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  27. Modified citrus pectins by UV/H2O2 oxidation at acidic and basic conditions: Structures and in vitro anti-inflammatory, anti-proliferative activities
    Authors: J Cao, J Yang, Z Wang, M Lu, K Yue
    Carbohydr Polym, 2020;247(0):116742.
    Species: Human
    Sample Types: Cell Culture Supernates
  28. NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells
    Authors: VM Abrahams, Z Tang, G Mor, S Guller
    J Reprod Immunol, 2020;142(0):103214.
    Species: Human
    Sample Types: Cell Culture Supernates
  29. Amyloid Beta Peptide (A&beta1-42) Reverses the Cholinergic Control of Monocytic IL-1&beta Release
    Authors: K Richter, R Ogiemwonyi, S Wilker, AI Chaveiro, A Agné, M Hecker, M Reichert, AL Amati, KD Schlüter, I Manzini, G Schmalzing, JM McIntosh, W Padberg, V Grau, A Hecker
    J Clin Med, 2020;9(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  30. An observational study of innate immune responses in patients with acute appendicitis
    Authors: T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens
    Sci Rep, 2020;10(1):17352.
    Species: Human
    Sample Types: Cell Culture Supernates
  31. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease
    Authors: X Zhang, R Wang, D Hu, X Sun, H Fujioka, K Lundberg, ER Chan, Q Wang, R Xu, ME Flanagan, AA Pieper, X Qi
    Science Advances, 2020;6(49):.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells
    Authors: V Panagiotak, D Ivanyuk, S De Cicco, W Haq, A Arsi?, C Yu, D Messelodi, M Oldrati, DC Schöndorf, MJ Perez, RP Cassatella, M Jakobi, N Schneiderh, T Gasser, I Niki?-Spie, M Deleidi
    Nat Commun, 2020;11(1):5163.
    Species: Human
    Sample Types: Whole Cells
  33. Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes
    Authors: M De, A Bhushan, S Chinnaswam
    J Leukoc Biol, 2020;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  34. Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans
    Authors: E Kaasinen, O Kuismin, K Rajamäki, H Ristolaine, M Aavikko, J Kondelin, S Saarinen, DG Berta, R Katainen, EAM Hirvonen, A Karhu, A Taira, T Tanskanen, A Alkodsi, M Taipale, E Morgunova, K Franssila, R Lehtonen, M Mäkinen, K Aittomäki, A Palotie, MI Kurki, O Pietiläine, M Hilpert, E Saarentaus, J Niinimäki, J Junttila, K Kaikkonen, P Vahteristo, RC Skoda, MRJ Seppänen, KK Eklund, J Taipale, O Kilpivaara, LA Aaltonen
    Nat Commun, 2019;10(1):1252.
    Species: Human
    Sample Types: Cell Culture Supernates
  35. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
    Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
    PLoS Pathog., 2019;15(4):e1007689.
    Species: Human
    Sample Types: Cell Culture Supernates
  36. Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
    Authors: C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong
    Mol. Cancer, 2019;18(1):64.
    Species: Human
    Sample Types: Cell Culture Supernates
  37. Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis
    Authors: L Su, P Pan, P Yan, Y Long, X Zhou, X Wang, R Zhou, B Wen, L Xie, D Liu
    Sci Rep, 2019;9(1):5747.
    Species: Human
    Sample Types: Cell Culture Supernates
  38. The effect of compressive force combined with mechanical vibration on human alveolar bone osteoblasts
    Authors: C Chatmahamo, A Pravithara, S Suttapreya, C Leethanaku
    J Oral Biol Craniofac Res, 2019;9(1):81-85.
    Species: Human
    Sample Types: Cell Culture Supernates
  39. Cervical cancer-instructed stromal fibroblasts enhance IL-23 expression in dendritic cells to support expansion of Th17 cells
    Authors: B Walch-Rück, R Ströder, L Theobald, J Pahne-Zepp, S Hegde, YJ Kim, RM Bohle, I Juhasz-Bös, EF Solomayer, S Smola
    Cancer Res., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  40. Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential
    Authors: D Raghunatha, PM Radford, C Gell, D Negus, C Moore, R Till, PJ Tighe, SP Wheatley, L Martinez-P, RE Sockett, J Tyson
    Sci Rep, 2019;9(1):4293.
    Species: Human
    Sample Types: Cell Culture Supernates
  41. In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists
    Authors: R Gramlich, E Aliahmadi, M Peiser
    Int J Mol Sci, 2019;20(6):.
    Species: Human
    Sample Types: Cell Culture Supernates
  42. Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells
    Authors: R Saga, K Hasegawa, K Murata, M Chiba, T Nakamura, K Okumura, E Tsuruga, Y Hosokawa
    Oncol Lett, 2019;17(3):3555-3561.
    Species: Human
    Sample Types: Cell Culture Supernates
  43. Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
    Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
    Nat Microbiol, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  44. Phenotypic and functional stability of leukocytes from human peripheral blood samples: considerations for the design of immunological studies
    Authors: A Navas, L Giraldo-Pa, MD Prieto, J Cabrera, MA Gómez
    BMC Immunol., 2019;20(1):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  45. Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages
    Authors: C Jumeau, F Awad, E Assrawi, L Cobret, P Duquesnoy, I Giurgea, D Valeyre, G Grateau, S Amselem, JF Bernaudin, SA Karabina
    PLoS ONE, 2019;14(5):e0217005.
    Species: Human
    Sample Types: Cell Culture Supernates
  46. Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages
    Authors: PJ Goddard, J Sanchez-Ga, SL Slater, M Kalyan, D Ruano-Gall, O Marchès, LÁ Fernández, G Frankel, AR Shenoy
    Cell Rep, 2019;27(4):1008-1017.e6.
    Species: Human
    Sample Types: Cell Culture Supernates
  47. Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation
    Authors: MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, AF McGettrick, CE Sutton, C Diskin, M Rooke, S Takahashi, S Sundararaj, MG Casarotto, JE Dahlstrom, EM Palsson-Mc, SC Corr, KHG Mills, RJS Preston, N Neamati, Y Xie, JB Baell, PG Board, LAJ O'Neill
    Cell Rep, 2019;29(1):151-161.e5.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
    Authors: S Dogra, M Wolf, MP Jeffrey, RCA Foley, H Logan-Spre, H Jones-Tagg, JM Green-John
    BMC Sports Sci Med Rehabil, 2019;11(0):23.
    Species: Human
    Sample Types: Saliva
  49. Physiologic intestinal 18F-FDG uptake is associated with alteration of gut microbiota and proinflammatory cytokine levels in breast cancer
    Authors: HJ Yoon, HN Kim, JI Bang, W Lim, BI Moon, NS Paik, BS Kim, HL Kim
    Sci Rep, 2019;9(1):18273.
    Species: Human
    Sample Types: Serum
  50. Inflammasome-Driven Interleukin-1α and�Interleukin-1? Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity
    Authors: X Jiang, F Wang, Y Wang, A Gisterå, J Roy, G Paulsson-B, U Hedin, A Lerman, GK Hansson, J Herrmann, ZQ Yan
    JACC Basic Transl Sci, 2019;4(3):304-317.
    Species: Human
    Sample Types: Tissue Culture Supernates
  51. Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
    Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
    MBio, 2019;10(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  52. β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
    Authors: JC Dos Santos, AM Barroso de, MV Teodoro Si, B Cirovic, LCJ de Bree, MSMA Damen, SJCFM Moorlag, RS Gomes, MM Helsen, M Oosting, ST Keating, A Schlitzer, MG Netea, F Ribeiro-Di, LAB Joosten
    Cell Rep, 2019;28(10):2659-2672.e6.
    Species: Human
    Sample Types: Cell Culture Supernates
  53. EASIX for prediction of survival in lower-risk myelodysplastic syndromes
    Authors: A Merz, U Germing, G Kobbe, J Kaivers, A Jauch, A Radujkovic, M Hummel, A Benner, M Merz, P Dreger, T Luft
    Blood Cancer J, 2019;9(11):85.
    Species: Human
    Sample Types: Plasma
  54. Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
    Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2019;60(14):4820-4829.
    Species: Human
    Sample Types: Cell Culture Supernates
  55. IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin
    Authors: I Tsilioni, AB Patel, H Pantazopou, S Berretta, P Conti, SE Leeman, TC Theoharide
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  56. The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1? by Human Cytomegalovirus through Inhibition of NF-kB Activity
    Authors: M Biolatti, V Dell'Oste, S Scutera, F Gugliesi, G Griffante, M De Andrea, T Musso, S Landolfo
    Viruses, 2018;10(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  57. Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism
    Authors: G Arbore, EE West, J Rahman, G Le Friec, N Niyonzima, M Pirooznia, I Tunc, P Pavlidis, N Powell, Y Li, P Liu, A Servais, L Couzi, V Fremeaux-B, L Placais, A Ferraro, PR Walsh, D Kavanagh, B Afzali, P Lavender, HJ Lachmann, C Kemper
    Nat Commun, 2018;9(1):4186.
    Species: Human
    Sample Types: Cell Culture Supernates
  58. Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease
    Authors: Q Zhang, H Li, S Hou, H Yu, G Su, B Deng, J Qi, C Zhou, A Kijlstra, P Yang
    Br J Ophthalmol, 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma
    Authors: T Kubo, M Tsujiwaki, Y Hirohashi, T Tsukahara, T Kanaseki, M Nakatsugaw, T Hasegawa, T Torigoe
    Lab. Invest., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  60. Sulphamethazine derivatives as immunomodulating agents: New therapeutic strategies for inflammatory diseases
    Authors: H Siddiqui, HM Haniffa, A Jabeen, AU -Rahman, MI Choudhary
    PLoS ONE, 2018;13(12):e0208933.
    Species: Human
    Sample Types: Cell Culture Supernates
  61. GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
    Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
    Nat Commun, 2018;9(1):3686.
    Species: Human
    Sample Types: Cell Culture Supernates
  62. CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
    Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
    Oncol Lett, 2018;15(6):9075-9080.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. Annexin A1, FPR2/ALX, and inflammatory cytokine expression in peritoneal endometriosis
    Authors: LK Volpato, VV Horewicz, F Bobinski, DF Martins, AP Piovezan
    J. Reprod. Immunol., 2018;129(0):30-35.
    Species: Human
    Sample Types: Peritoneal Fluid
  64. S100B regulates inflammatory response during osteoarthritis via fibroblast growth factor receptor 1 signaling
    Authors: L Zhu, Z Weng, P Shen, J Zhou, J Zeng, F Weng, X Zhang, H Yang
    Mol Med Rep, 2018;18(6):4855-4864.
    Species: Human
    Sample Types: Cell Culture Supernates
  65. A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
    Authors: LBS Hansen, HM Roager, NB Søndertoft, RJ Gøbel, M Kristensen, M Vallès-Col, S Vieira-Sil, S Ibrügger, MV Lind, RB Mærkedahl, MI Bahl, ML Madsen, J Havelund, G Falony, I Tetens, T Nielsen, KH Allin, HL Frandsen, B Hartmann, JJ Holst, MH Sparholt, J Holck, A Blennow, JM Moll, AS Meyer, C Hoppe, JH Poulsen, V Carvalho, D Sagnelli, MD Dalgaard, AF Christense, MC Lydolph, AB Ross, S Villas-Bôa, S Brix, T Sicheritz-, K Buschard, A Linneberg, JJ Rumessen, CT Ekstrøm, C Ritz, K Kristianse, HB Nielsen, H Vestergaar, NJ Færgeman, J Raes, H Frøkiær, T Hansen, L Lauritzen, R Gupta, TR Licht, O Pedersen
    Nat Commun, 2018;9(1):4630.
    Species: Human
    Sample Types: Cell Culture Supernates
  66. PDGF enhances the protective effect of adipose stem cell-derived extracellular vesicles in a model of acute hindlimb ischemia
    Authors: T Lopatina, E Favaro, C Grange, M Cedrino, A Ranghino, S Occhipinti, S Fallo, F Buffolo, DA Gaykalova, MM Zanone, R Romagnoli, G Camussi
    Sci Rep, 2018;8(1):17458.
    Species: Human
    Sample Types: Cell Culture Supernates
  67. A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
    Authors: M Mastri, A Tracz, CR Lee, M Dolan, K Attwood, JG Christense, S Liu, JML Ebos
    Cell Rep, 2018;25(13):3706-3720.e8.
    Species: Human
    Sample Types: Cell Culture Supernates
  68. Combining Calcium Phosphates with Polysaccharides: A Bone-Inspired Material Modulating Monocyte/Macrophage Early Inflammatory Response
    Authors: H Rammal, C Bour, M Dubus, L Entz, L Aubert, SC Gangloff, S Audonnet, NB Bercu, F Boulmedais, C Mauprivez, H Kerdjoudj
    Int J Mol Sci, 2018;19(11):.
    Species: Human
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  69. A central role for P2X7 receptors in human microglia
    Authors: L Janks, CVR Sharma, TM Egan
    J Neuroinflammation, 2018;15(1):325.
    Species: Human
    Sample Types: Cell Culture Supernates
  70. Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages
    Authors: T Karasawa, A Kawashima, F Usui-Kawan, S Watanabe, H Kimura, R Kamata, K Shirasuna, Y Koyama, A Sato-Tomit, T Matsuzaka, H Tomoda, SY Park, N Shibayama, H Shimano, T Kasahara, M Takahashi
    Arterioscler. Thromb. Vasc. Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  71. Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus
    Authors: L Laencina, V Dubois, V Le Moigne, A Viljoen, L Majlessi, J Pritchard, A Bernut, L Piel, AL Roux, JL Gaillard, B Lombard, D Loew, EJ Rubin, R Brosch, L Kremer, JL Herrmann, F Girard-Mis
    Proc. Natl. Acad. Sci. U.S.A., 2018;115(5):E1002-E1011.
    Species: Human
    Sample Types: Cell Culture Supernates
  72. Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages
    Authors: AMV Murthy, MD Phan, KM Peters, NTK Nhu, RA Welch, GC Ulett, MA Schembri, MJ Sweet
    Virulence, 2018;0(0):1-32.
    Species: Human
    Sample Types: Cell Culture Supernates
  73. Clinical predictors of liver fibrosis in patients with chronic hepatitis B virus infection from children to adults
    Authors: JF Wu, SH Song, CS Lee, HL Chen, YH Ni, HY Hsu, TC Wu, MH Chang
    J. Infect. Dis., 2018;0(0):.
    Species: Human
    Sample Types: Serum
  74. Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface
    Authors: I Tomašek, CJ Horwell, C Bisig, DE Damby, P Comte, J Czerwinski, A Petri-Fink, MJD Clift, B Drasler, B Rothen-Rut
    Environ. Pollut., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  75. Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
    Authors: R Narasimhan, R Coras, SB Rosenthal, SR Sweeney, A Lodi, S Tiziani, D Boyle, A Kavanaugh, M Guma
    Arthritis Res. Ther., 2018;20(1):164.
    Species: Human
    Sample Types: Serum
  76. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
    Authors: B Lagrange, S Benaoudia, P Wallet, F Magnotti, A Provost, F Michal, A Martin, F Di Lorenzo, BF Py, A Molinaro, T Henry
    Nat Commun, 2018;9(1):242.
    Species: Human
    Sample Types: Cell Culture Supernates
  77. Analysis of the association between Fc receptor family gene polymorphisms and ocular Beh�et's disease in Han Chinese
    Authors: D Zhang, J Qin, L Li, G Su, G Huang, Q Cao, A Kijlstra, P Yang
    Sci Rep, 2018;8(1):4850.
    Species: Human
    Sample Types: Cell Culture Supernates
  78. TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
    Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
    Eur Cell Mater, 2018;35(0):13-24.
  79. The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models
    Authors: RF Hamilton, Z Wu, S Mitra, A Holian
    Int J Mol Sci, 2018;19(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  80. Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
    Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
    Invest. Ophthalmol. Vis. Sci., 2018;59(2):1158-1166.
    Species: Human
    Sample Types: Cell Culture Supernates
  81. Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
    Authors: BA McKenzie, MK Mamik, LB Saito, R Boghozian, MC Monaco, EO Major, JQ Lu, WG Branton, C Power
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  82. TET-2 up-regulation is associated with the anti-inflammatory action of Vicenin-2
    Authors: N Hassan, A Ali, C Withycombe, M Ahluwalia, RH Al-Nasseri, A Tonks, K Morris
    Cytokine, 2018;108(0):37-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  83. Vaccine antigens modulate the innate response of monocytes to Al(OH)3
    Authors: S Kooijman, J Brummelman, CACM van Els, F Marino, AJR Heck, E van Riet, B Metz, GFA Kersten, JLA Pennings, HD Meiring
    PLoS ONE, 2018;13(5):e0197885.
    Species: Human
    Sample Types: Cell Culture Supernates
  84. Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
    Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
    Sci Rep, 2017;7(1):1815.
    Species: Human
    Sample Types: Cell Culture Supernates
  85. Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
    Authors: L Chen, MS Eapen, GR Zosky
    Sci Rep, 2017;7(0):45172.
    Species: Human
    Sample Types: Cell Culture Supernates
  86. Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
    Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
    Immun Ageing, 2017;14(0):5.
    Species: Human
    Sample Types: Cell Culture Supernates
  87. Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF-? and IL-1? in third molar surgery: a triple-blind, randomized, placebo-controlled study
    Authors: AFM Albuquerqu, CSR Fonteles, DR do Val, HV Chaves, MM Bezerra, KMA Pereira, PG de Barros, BB de Lima, ECS Soares, TR Ribeiro, FWG Costa
    Int J Oral Maxillofac Surg, 2017;0(0):.
    Species: Human
    Sample Types: Tissue Homogenates
  88. Induction of immune gene expression and inflammatory mediator release by commonly used surgical suture materials: an experimental in vitro study
    Authors: AM Lock, R Gao, D Naot, B Coleman, J Cornish, DS Musson
    Patient Saf Surg, 2017;11(0):16.
    Species: Human
    Sample Types: Cell Culture Supernates
  89. In vitro effects of hyaluronic acid on human periodontal ligament cells
    Authors: M Fujioka-Ko, HD Mller, A Mueller, A Lussi, A Sculean, PR Schmidlin, RJ Miron
    BMC Oral Health, 2017;17(1):44.
    Species: Human
    Sample Types: Cell Culture Supernates
  90. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
    Authors: SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G N£¤ez, SL Masters, JM Murphy, K Schroder, DL Vaux, KE Lawlor, LM Lindqvist, JE Vince
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  91. An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition
    Authors: HL Young, EJ Rowling, M Bugatti, E Giurisato, N Luheshi, I Arozarena, JC Acosta, J Kamarashev, DT Frederick, ZA Cooper, A Reuben, J Gil, KT Flaherty, JA Wargo, W Vermi, MP Smith, C Wellbrock, A Hurlstone
    J. Exp. Med., 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  92. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface
    Authors: LM Scott, AH Bryant, A Rees, B Down, RH Jones, CA Thornton
    Cytokine, 2017;0(0):.
    Species: Human
    Sample Types: Tissue Culture Supernates
  93. Iron nanomedicines induce Toll-like receptor activation, cytokine production and complement activation
    Authors: Johan J F Verhoef
    Biomaterials, 2017;119(0):68-77.
    Species: Human
    Sample Types: Cell Culture Supernates
  94. Altered distribution of peripheral blood dendritic cell subsets in patients with pulmonary paracoccidioidomycosis
    Authors: J Venturini, RS Cavalcante, DV Moris, M de Assis G, AD Levorato, KH Dos Reis, MSP de Arruda, RP Mendes
    Acta Trop., 2017;0(0):.
    Species: Human
    Sample Types: Serum
  95. Rheumatoid arthritis bone marrow environment supports Th17 response
    Authors: E Kuca-Warna, W Kurowska, M Prochorec-, A Radzikowsk, T Burakowski, U Skalska, M Massalska, M Pleba?czyk, B Ma?dyk-Now, I S?owi?ska, R Gasik, W Ma?li?ski
    Arthritis Res. Ther., 2017;19(1):274.
    Species: Human
    Sample Types: Plasma
  96. Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response
    Authors: S Das, M Raundhal, J Chen, TB Oriss, R Huff, JV Williams, A Ray, P Ray
    JCI Insight, 2017;2(17):.
    Species: Human
    Sample Types: Cell Culture Supernates
  97. Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation
    Authors: S Zwicker, E Hattinger, D Bureik, A Batycka-Ba, A Schmidt, PA Gerber, S Rothenfuss, M Gilliet, T Ruzicka, R Wolf
    PLoS ONE, 2017;12(4):e0175153.
    Species: Human
    Sample Types: Cell Culture Supernates
  98. TB lymphadenitis is associated with enhanced baseline and antigen - specific induction of Type 1 and Type 17 cytokines and reduced IL-1? and IL-18 at the site of infection
    Authors: GR Kathamuthu, K Moideen, D Baskaran, VV Banurekha, D Nair, G Sekar, R Sridhar, B Vidyajayan, G Gajendrara, DK Parandhama, A Srinivasan, S Babu
    Clin. Vaccine Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  99. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study
    Authors: J Vandooren, S Knoops, JL Aldinucci, L Boon, E Martens, G Opdenakker, E Kolaczkows
    PLoS ONE, 2017;12(4):e0174853.
    Species: Human
    Sample Types: Cell Culture Supernates
  100. Rheumatoid arthritis bone marrow environment supports Th17 response.
    Authors: Ewa Kuca-Warna, Weronika Kurowska, Monika Prochorec, Anna Radzikows, Tomasz Burakowsk, Urszula Skalska, Magdalena Massalska, Magdalena Pleba?czy, Barbara Ma?dyk-No, Iwona S?owi?ska, Robert Gasik, W?odzimierz Ma?li?ski
    Arthritis Research & Therapy, 2017;0(0):1478-6362.
    Species: Human
    Sample Types: Plasma
  101. Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT
    Authors: S Dabo, P Maillard, M Collados R, MD Hansen, S Mazouz, DJ Bigot, M Tible, G Janvier, O Helynck, P Cassonnet, Y Jacob, J Bellalou, A Gatignol, RC Patel, J Hugon, H Munier-Leh, EF Meurs
    Sci Rep, 2017;7(1):16129.
    Species: Human
    Sample Types: Cell Culture Supernates
  102. Elevated CRP levels predict poor outcome and tumor recurrence in patients with thymic epithelial tumors: A pro- and retrospective analysis
    Authors: S Janik, C Bekos, P Hacker, T Raunegger, B Ghanim, E Einwallner, L Beer, W Klepetko, L Müllauer, HJ Ankersmit, B Moser
    Oncotarget, 2017;8(29):47090-47102.
    Species: Human
    Sample Types: Serum
  103. In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens
    Authors: N Goli?, K Veljovi?, N Popovi?, J Djoki?, I Strahini?, I Mrvaljevi?, A Terzi?-Vid
    BMC Microbiol., 2017;17(1):108.
    Species: Human
    Sample Types: Cell Culture Supernates
  104. IL-18 associated with lung lymphoid aggregates drives IFN? production in severe COPD
    Authors: E Briend, GJ Ferguson, M Mori, G Damera, K Stephenson, NA Karp, S Sethi, CK Ward, MA Sleeman, JS Erjefält, DK Finch
    Respir. Res., 2017;18(1):159.
    Species: Human
    Sample Types: Cell Culture Supernates
  105. The Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes.
    Authors: Simanski M, Rademacher F, Schroder L, Glaser R, Harder J
    PLoS ONE, 2016;11(1):e0147118.
    Species: Human
    Sample Types: Cell Culture Supernates
  106. Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
    Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
    J Leukoc Biol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  107. Dental Calculus Stimulates Interleukin-1? Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes
    Authors: JL Montenegro, A Yoshimura, Z Sm, T Kaneko, Y Ozaki, T Ukai, T Miyazaki, E Latz, Y Hara
    PLoS ONE, 2016;11(9):e0162865.
    Species: Human
    Sample Types: Cell Culture Supernates
  108. Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1? and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  109. Biocompatibility of primers and an adhesive used for implant-retained maxillofacial prostheses: An in�vitro analysis
    Authors: Daniela Micheline Dos Santos
    J Prosthet Dent, 2016;0(0):.
  110. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
    Sci Rep, 2016;6(0):39035.
    Species: Human
    Sample Types: Cell Culture Supernates
  111. Receptor-Type Protein-Tyrosine Phosphatase ? and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1
    PLoS ONE, 2016;11(11):e0167324.
    Species: Human
    Sample Types: Cell Culture Supernates
  112. Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
    Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
    PLoS ONE, 2016;11(4):e0153118.
    Species: Human
    Sample Types: Cell Culture Supernates
  113. Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?
    Aging Cell, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  114. Graphene-augmented nanofiber scaffolds demonstrate new features in cells behaviour
    Sci Rep, 2016;6(0):30150.
    Species: Human
    Sample Types: Cell Culture Supernates
  115. Interleukin-17A Induces IL-1? Secretion From RPE Cells Via the NLRP3 Inflammasome
    Authors: S Zhang, N Yu, R Zhang, S Zhang, J Wu
    Invest. Ophthalmol. Vis. Sci, 2016;57(2):312-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  116. 17-oxo-DHA displays additive anti-inflammatory effects with fluticasone propionate and inhibits the NLRP3 inflammasome
    Sci Rep, 2016;6(0):37625.
    Species: Human
    Sample Types: Cell Culture Supernates
  117. Reduced systemic and mycobacterial antigen-stimulated concentrations of IL-1? and IL-18 in tuberculous lymphadenitis
    Cytokine, 2016;90(0):66-72.
    Species: Human
    Sample Types: Cell Culture Supernates
  118. DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  119. Combined exposure of diesel exhaust particles and respirable Soufri�re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
    Authors: Ines Tomašek
    Part Fibre Toxicol, 2016;13(1):67.
    Species: Human
    Sample Types: Cell Culture Supernates
  120. Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
    PLoS Pathog, 2016;12(9):e1005871.
    Species: Human
    Sample Types: Cell Culture Supernates
  121. Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide
    Sci Rep, 2016;6(0):36575.
    Species: Human
    Sample Types: Cell Culture Supernates
  122. Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
    Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
    Sci Rep, 2016;6(0):24974.
    Species: Human
    Sample Types: Cell Culture Supernates
  123. Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease
    Sci Rep, 2016;6(0):26662.
    Species: Human
    Sample Types: Cell Culture Supernates
  124. Silk-based blood stabilization for diagnostics
    Proc Natl Acad Sci USA, 2016;113(21):5892-7.
    Species: Human
    Sample Types: Serum
  125. CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection
    PLoS Pathog, 2016;12(7):e1005770.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  126. Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
    Authors: Avery D Posey
    Immunity, 2016;44(6):1444-54.
    Species: Human
    Sample Types: Cell Culture Supernates
  127. Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion
    Authors: Mélissa Noack
    Arthritis Res Ther, 2016;18(0):148.
    Species: Human
    Sample Types: Cell Culture Supernates
  128. Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1beta, IFN-beta, and IL-15 Pathways.
    Authors: Mattiola I, Pesant M, Tentorio P, Molgora M, Marcenaro E, Lugli E, Locati M, Mavilio D
    J Immunol, 2015;195(6):2818-28.
    Species: Human
    Sample Types: Cell Culture Supernates
  129. Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
    Authors: Karmakar M, Katsnelson M, Malak H, Greene N, Howell S, Hise A, Camilli A, Kadioglu A, Dubyak G, Pearlman E
    J Immunol, 2015;194(4):1763-75.
    Species: Human
    Sample Types: Cell Culture Supernates
  130. Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.
    Authors: Schupp J, Binder H, Jager B, Cillis G, Zissel G, Muller-Quernheim J, Prasse A
    PLoS ONE, 2015;10(1):e0116775.
    Species: Human
    Sample Types: BALF
  131. In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
    Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
    Reprod Biol Endocrinol, 2015;13(0):115.
    Species: Human
    Sample Types: Cell Culture Supernates
  132. Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women.
    Authors: McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K
    PLoS ONE, 2015;10(8):e0134619.
    Species: Human
    Sample Types: Plasma
  133. Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter.
    Authors: Brand O, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson A, Hill A, Jablons D, Wolters P, Lou J, Marks J, Baron J, Nishimura S
    J Biol Chem, 2015;290(23):14717-28.
    Species: Human
    Sample Types: Tissue Homogenates
  134. LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease.
    Authors: Broekman M, Roelofs H, Hoentjen F, Wiegertjes R, Stoel N, Joosten L, de Jong D, Wanten G
    PLoS ONE, 2015;10(7):e0133932.
    Species: Human
    Sample Types: Plasma
  135. Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.
    Authors: Antonopoulos C, Russo H, El Sanadi C, Martin B, Li X, Kaiser W, Mocarski E, Dubyak G
    J Biol Chem, 2015;290(33):20167-84.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. SRSF1 facilitates cytosolic DNA-induced production of type I interferons recognized by RIG-I.
    Authors: Xue F, Li X, Zhao X, Wang L, Liu M, Shi R, Zheng J
    PLoS ONE, 2015;10(2):e0115354.
    Species: Human
    Sample Types: Cell Culture Supernates
  137. The effect of size on Ag nanosphere toxicity in macrophage cell models and lung epithelial cell lines is dependent on particle dissolution.
    Authors: Hamilton, Raymond, Buckingham, Sarah, Holian, Andrij
    Int J Mol Sci, 2014;15(4):6815-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  138. Activin A as a mediator of NK-dendritic cell functional interactions.
    Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
    J Immunol, 2014;192(3):1241-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  139. A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
    Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
    PLoS ONE, 2014;9(5):e96943.
    Species: Human
    Sample Types: Cell Culture Supernates
  140. Integrin alphaDbeta2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.
    Authors: Miyazaki Y, Vieira-de-Abreu A, Harris E, Shah A, Weyrich A, Castro-Faria-Neto H, Zimmerman G
    PLoS ONE, 2014;9(11):e112770.
    Species: Human
    Sample Types: Cell Culture Supernates
  141. Angiopoietin-1 upregulates de novo expression of IL-1beta and Il1-Ra, and the exclusive release of Il1-Ra from human neutrophils.
    Authors: Haddad L, Sirois M
    PLoS ONE, 2014;9(2):e88980.
    Species: Human
    Sample Types: Cell Lysates
  142. Kineret(R)/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection.
    Authors: Labrousse D, Perret M, Hayez D, da Silva S, Badiou C, Couzon F, Bes M, Chavanet P, Lina G, Vandenesch F, Croisier-Bertin D, Henry T
    PLoS ONE, 2014;9(6):e97546.
  143. Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells.
    Authors: Schwarz H, Schmittner M, Duschl A, Horejs-Hoeck J
    PLoS ONE, 2014;9(12):e113840.
    Species: Human
    Sample Types: Cell Culture Supernates
  144. The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.
    Authors: Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F
    J Biol Chem, 2014;289(3):1364-76.
  145. Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
    Authors: Zughaier, Susu M, Kandler, Justin L, Shafer, William
    PLoS ONE, 2014;9(1):e87688.
    Species: Human
    Sample Types: Cell Culture Supernates
  146. TLR ligands stimulation protects MSC from NK killing.
    Authors: Giuliani M, Bennaceur-Griscelli A, Nanbakhsh A, Oudrhiri N, Chouaib S, Azzarone B, Durrbach A, Lataillade J
    Stem Cells, 2014;32(1):290-300.
    Species: Human
    Sample Types: Cell Culture Supernates
  147. Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
    Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
    J Biol Chem, 2014;289(27):19231-44.
    Species: Human
    Sample Types: Cell Culture Supernates
  148. Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population.
    Authors: Fang J, Hu R, Hou S, Ye Z, Xiang Q, Qi J, Zhou Y, Kijlstra A, Yang P
    Invest Ophthalmol Vis Sci, 2013;54(13):8384-92.
    Species: Human
    Sample Types: Cell Culture Supernates
  149. S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
    Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
    PLoS ONE, 2013;8(4):e62372.
  150. Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
    Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
    Cytokine, 2013;65(2):222-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  151. Inflammasome induction in Rasmussen's encephalitis: cortical and associated white matter pathogenesis.
    Authors: Ramaswamy V, Walsh J, Sinclair D, Johnson E, Tang-Wai R, Wheatley B, Branton W, Maingat F, Snyder T, Gross D, Power C
    J Neuroinflammation, 2013;10(0):152.
    Species: Human
    Sample Types: Cell Culture Supernates
  152. Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
    Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
    PLoS ONE, 2013;8(12):e82734.
    Species: Human
    Sample Types: Cell Culture Supernates
  153. Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
    Eur J Clin Nutr, 2012;66(9):1072-4.
    Species: Human
    Sample Types: Serum
  154. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
    Authors: Suh HS, Choi N, Tarassishin L, Lee SC
    PLoS ONE, 2012;7(4):e35115.
    Species: Human
    Sample Types: Cell Culture Supernates
  155. Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.
    J. Exp. Med., 2012;209(8):1505-17.
    Species: Human
    Sample Types: Cell Culture Supernates
  156. Monocytic microparticles activate endothelial cells in an IL-1{beta}-dependent manner.
    Authors: Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N
    Blood, 2011;118(8):2366-74.
    Species: Human
    Sample Types: Cell Lysates
  157. Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
    Authors: van de Veerdonk FL, Smeekens SP, Joosten LA, Kullberg BJ, Dinarello CA, Van der Meer JW, Netea MG
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3030-3.
    Species: Human
    Sample Types: Cell Culture Supernates
  158. Interleukin (IL)-31 induces pro-inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins.
    Authors: Kasraie S, Niebuhr M, Werfel T
    Allergy, 2010;65(6):712-21.
    Species: Human
    Sample Types: Cell Culture Supernates
  159. Maternal IL-1beta production prevents lung injury in a mouse model of bronchopulmonary dysplasia.
    Authors: Backstrom E, Lappalainen U, Bry K
    Am. J. Respir. Cell Mol. Biol., 2010;42(2):149-60.
    Species: Human
    Sample Types: Tissue Homogenates
  160. Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
    Authors: Correale J, Farez M
    J. Immunol., 2009;183(9):5999-6012.
    Species: Human
    Sample Types: Cell Culture Supernates
  161. Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia.
    Authors: Lukkarinen H, Hogmalm A, Lappalainen U, Bry K
    Am. J. Respir. Cell Mol. Biol., 2009;41(1):59-68.
    Species: Human
    Sample Types: Tissue Homogenates
  162. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009;119(10):1424-32.
    Species: Human
    Sample Types: Plasma
  163. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages.
    Authors: Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H
    Eur. J. Immunol., 2009;39(3):820-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  164. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
    Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
    Eur. J. Immunol., 2009;39(5):1221-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  165. Divergent effects of hypoxia on dendritic cell functions.
    Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A
    Blood, 2008;112(9):3723-34.
    Species: Human
    Sample Types: Cell Culture Supernates
  166. Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
    Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
    J. Cell. Physiol., 2008;214(1):27-37.
    Species: Human
    Sample Types: Cell Culture Supernates
  167. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
    Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
    J. Biol. Chem., 2007;282(44):31882-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  168. Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis.
    Authors: Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C
    J. Immunol., 2007;179(10):7166-75.
    Species: Human
    Sample Types: Urine
  169. Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors.
    Authors: Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H
    Cytokine, 2007;34(5):278-83.
    Species: Human
    Sample Types: Serum
  170. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.
    Authors: Duluc D, Delneste Y, Tan F, Moles MP, Grimaud L, Lenoir J, Preisser L, Anegon I, Catala L, Ifrah N, Descamps P, Gamelin E, Gascan H, Hebbar M, Jeannin P
    Blood, 2007;110(13):4319-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  171. Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
    Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
    J. Clin. Invest., 2007;117(12):3664-3672.
    Species: Human
    Sample Types: Cell Culture Supernates
  172. Sepsis and pathophysiology of anthrax in a nonhuman primate model.
    Authors: Stearns-Kurosawa DJ, Lupu F, Taylor FB, Kinasewitz G, Kurosawa S
    Am. J. Pathol., 2006;169(2):433-44.
    Species: Primate - Papio cynocephalus (Yellow Baboon)
    Sample Types: Plasma
  173. Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
    Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
    J. Pharmacol. Exp. Ther., 2006;318(2):741-50.
    Species: Human
    Sample Types: Cell Culture Supernates
  174. B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease.
    Authors: Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA
    Am. J. Pathol., 2006;169(3):987-98.
    Species: Human
    Sample Types: Tissue Homogenates
  175. Increased ENA-78 in the follicular fluid of patients with endometriosis.
    Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
    Acta Obstet Gynecol Scand, 2006;85(3):336-42.
    Species: Human
    Sample Types: Follicular Fluid
  176. Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing.
    Authors: Anderson ST, Williams AJ, Brown JR, Newton SM, Simsova M, Nicol MP, Sebo P, Levin M, Wilkinson RJ, Wilkinson KA
    Am. J. Respir. Crit. Care Med., 2006;173(9):1038-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  177. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
    Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
    Eur. J. Immunol., 2005;35(8):2459-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  178. Differential effect of serotonin on cytokine production in lipopolysaccharide-stimulated human peripheral blood mononuclear cells: involvement of 5-hydroxytryptamine2A receptors.
    Authors: Cloez-Tayarani I, Petit-Bertron AF, Venters HD, Cavaillon JM
    Int. Immunol., 2003;15(2):233-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  179. Adherence influences monocyte responsiveness to interleukin-10.
    Authors: Petit-Bertron AF, Fitting C, Cavaillon JM, Adib-Conquy M
    J. Leukoc. Biol., 2003;73(1):145-54.
    Species: Human
    Sample Types: Cell Culture Supernates
  180. The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
    Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
    Hum. Reprod., 2002;17(4):1039-45.
    Species: Human
    Sample Types: Peritoneal Fluid
  181. IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions.
    Authors: Cheong YC, Shelton JB, Laird SM, Richmond M, Kudesia G, Li TC, Ledger WL
    Hum. Reprod., 2002;17(1):69-75.
    Species: Human
    Sample Types: Peritoneal Fluid
  182. Comparison of inflammatory elements in nasal lavage and induced sputum following occupational exposure to moldy-building microbes.
    Authors: Purokivi M, Hirvonen MR, Roponen M, Randell J, Vahteristo M, Tukiainen H
    Inhal Toxicol, 2002;14(6):653-62.
    Species: Human
    Sample Types: Sputum
  183. Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders.
    Authors: Roponen M, Kiviranta J, Seuri M, Tukiainen H, Myllykangas-Luosujarvi R, Hirvonen MR
    Eur. Respir. J., 2001;18(3):542-8.
    Species: Human
    Sample Types: Serum

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Reviews for Human IL-1 beta/IL-1F2 DuoSet ELISA

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Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 06/25/2021
Application: Sample Tested: Human cell conditioned medium
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/12/2021
Application: Sample Tested: Cell culture supernatant
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/01/2021
Application: Sample Tested: THP-1 human acute monocytic leukemia cell line

THP-1 cells were incubated with 0.1-10ug/ml PAM3CSK4 for 24-hours and culture supernatant was collected. IL-1b standard was fit to a sigmoidal 4-paramater logistic curve. Max IL-1b production was found at the 1ug/ml dosage.

Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/09/2020
Application: Sample Tested: Reconstituted Human Ciliated Airway

3D ciliated airway tissues (cat.# 502-3D-24) were from Cell Applications (San Diego, CA) and were cultured in maintenance medium (cat.# 511M-3D-100, Cell Applications).
Twenty four hours after pre-incubation with test substances, tissues were exposed to 1µg/ml endotoxin LPS and IL-1b was was quantified after 48 additional hours. Worked very well.

Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/29/2020
Application: Sample Tested: Tissue Culture Media

Detection of IL-1b secreted by human CAR-T cells engineered to express IL-1b (PMC658), compared to normal CAR-T cells (PMC650).

Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 08/11/2020
Application: Sample Tested: Serum and Plasma
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/11/2020
Application: Sample Tested: K562 human chronic myelogenous leukemia cell line
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 01/15/2020
Application: Sample Tested: Cell culture supernatant
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/14/2019
Application: Sample Tested: MICROGLIA CELLS
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/14/2019
Application: Sample Tested: Microglia cells
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/11/2019
Application: Sample Tested: human PBMC
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/02/2019
Application: Sample Tested: Cell culture supernatant

Not compatible with all substrates.

Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 01/03/2019
Application: Sample Tested: Cell Lysates
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 11/26/2018
Application: Sample Tested: Plasma
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 10/07/2018
Application: Sample Tested: EDTA Plasma
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/03/2018
Application: Sample Tested: THP-1 human acute monocytic leukemia cell line
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/12/2018
Application: Sample Tested: Cell culture supernatant
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 03/30/2018
Application: Sample Tested: Serum
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/27/2018
Application: Sample Tested: 7TD1 mouse hybridoma cell line,Human Whole Blood
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/06/2018
Application: Sample Tested: Bone marrow-derived dendritic cells
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 01/25/2018
Application: Sample Tested: THP-1 human acute monocytic leukemia cell line
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 10/17/2017
Application: Sample Tested: U937 human histiocytic lymphoma cell line
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/08/2017
Application: Sample Tested: Activated mouse CD8 T cell
Human IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/03/2017
Application: Sample Tested: Human Serum
Serum Human IL-1 beta/IL-1F2 DuoSet ELISA DY201
Human IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate
By Anonymous on 04/04/2016
Application: Sample Tested: THP-1 human acute monocytic leukemia cell line,Various primary cells