Human IL-1 beta/IL-1F2 DuoSet ELISA

A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistance
Authors: H Chen, ME Diolaiti, PC O'Leary, A Rojc, NJ Krogan, M Kim, A Ashworth
Molecular Cancer Therapeutics, 2022;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement
Authors: C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert
International Journal of Molecular Sciences, 2022;23(3):.
Species: Human
Sample Types: Cell Culture Supernates

"HIIT the Inflammation": Comparative Effects of Low-Volume Interval Training and Resistance Exercises on Inflammatory Indices in Obese Metabolic Syndrome Patients Undergoing Caloric Restriction
Authors: D Reljic, W Dieterich, HJ Herrmann, MF Neurath, Y Zopf
Nutrients, 2022;14(10):.
Species: Human
Sample Types: Serum

Green and Roasted Coffee Extracts Inhibit Interferon-beta Release in LPS-Stimulated Human Macrophages
Authors: V Artusa, C Ciaramelli, A D'Aloia, FA Facchini, N Gotri, A Bruno, B Costa, A Palmioli, C Airoldi, F Peri
Frontiers in Pharmacology, 2022;13(0):806010.
Species: Human
Sample Types: Cell Culture Supernates

Discovery of a novel GRPR antagonist for protection against cisplatin-induced acute kidney injury
Authors: MJ Yu, C Li, SS Deng, XM Meng, RS Yao
Bioorganic chemistry, 2022;124(0):105794.
Species: Human
Sample Types: Cell Culture Supernates

Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells
Authors: M Busch, G Bredeck, F Waag, K Rahimi, H Ramachandr, T Bessel, S Barcikowsk, A Herrmann, A Rossi, RPF Schins
Biomolecules, 2022;12(8):.
Species: Human
Sample Types: Cell Culture Supernates

PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical beta-coronavirus disease
Authors: M Duhalde Ve, D Olivera, G Gastão Dav, M Bertullo, V Noya, G Fabiano de, S Primon Mur, I Castro, AP Arévalo, M Crispo, G Galliussi, S Russo, D Charbonnie, F Rammauro, M Jeldres, C Alamón, V Varela, C Batthyany, M Bollati-Fo, P Oppezzo, O Pritsch, JL Proença-Mó, HI Nakaya, E Trias, L Barbeito, I Anegon, MC Cuturi, P Moraes-Vie, M Segovia, M Hill
Science Advances, 2022;8(38):eabn6545.
Species: Human
Sample Types: Cell Culture Supernates

Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling
Authors: J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li
International journal of biological sciences, 2022;18(11):4545-4559.
Species: Human
Sample Types: Cell Culture Supernates

Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS
Authors: W Dieterich, C Schuster, P Gundel, KA Scherf, D Pronin, S Geisslitz, A Börner, MF Neurath, Y Zopf
Nutrients, 2022;14(20):.
Species: Human
Sample Types: Cell Culture Supernates

Development of an Electrochemical CCL5 Chemokine Immunoplatform for Rapid Diagnosis of Multiple Sclerosis
Authors: S Guerrero, E Sánchez-Ti, L Agüí, A González-C, P Yáñez-Sede, JM Pingarrón
Biosensors, 2022;12(8):.
Species: Human
Sample Types: Serum

Signal strength of STING activation determines cytokine plasticity and cell death in human monocytes
Authors: D Kabelitz, M Zarobkiewi, M Heib, R Serrano, M Kunz, G Chitadze, D Adam, C Peters
Scientific Reports, 2022;12(1):17827.
Species: Human
Sample Types: Cell Culture Supernates

T Lymphocyte Serotonin 5-HT7 Receptor Is Dysregulated in Natalizumab-Treated Multiple Sclerosis Patients
Authors: F Reverchon, C Guillard, L Mollet, P Auzou, D Gosset, F Madouri, A Valéry, A Menuet, C Ozsancak, M Pallix-Guy, S Morisset-L
Biomedicines, 2022;10(10):.
Species: Human
Sample Types: Plasma

Interleukin-17, a salivary biomarker for COVID-19 severity
Authors: FS Sharif-Ask, NS Sharif-Ask, S Hafezi, B Mdkhana, HAH Alsayed, AW Ansari, B Mahboub, AM Zakeri, MH Temsah, W Zahir, Q Hamid, R Halwani
PLoS ONE, 2022;17(9):e0274841.
Species: Human
Sample Types: Saliva

Toxoplasma gondii Rhoptry Protein 7 (ROP7) Interacts with NLRP3 and Promotes Inflammasome Hyperactivation in THP-1-Derived Macrophages
Authors: L Zhu, W Qi, G Yang, Y Yang, Y Wang, L Zheng, Y Fu, X Cheng
Cells, 2022;11(10):.
Species: Human
Sample Types: Cell Culture Supernates

Antibacterial and Anti-Inflammatory Effects of Apolipoprotein E
Authors: M Puthia, JK Marzinek, G Petruk, G Ertürk Ber, PJ Bond, J Petrlova
Biomedicines, 2022;10(6):.
Species: Human
Sample Types: Plasma

Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation
Authors: K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi
Scientific Reports, 2022;12(1):5181.
Species: Human
Sample Types: Cell Culture Supernates

The Restorative Effect of Human Amniotic Fluid Stem Cells on Spinal Cord Injury
Authors: M Lale Ataei, M Karimipour, P Shahabi, R Pashaei-As, E Ebrahimie, M Pashaiasl
Cells, 2021;10(10):.
Species: Rat
Sample Types: Cell Culture Supernates

Low levels of PCSK9 are associated with remission in patients with rheumatoid arthritis treated with anti-TNF-&alpha: potential underlying mechanisms
Authors: J Frostegård, S Ahmed, I Hafström, S Ajeganova, M Rahman
Arthritis Research & Therapy, 2021;23(1):32.
Species: Human
Sample Types: Cell Culture Supernates

Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
Authors: N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton
Nature Communications, 2021;12(1):1209.
Species: Human
Sample Types: Cell Culture Supernates

Synthetic Material Abdominal Swabs Reduce Activation of Platelets and Leukocytes Compared to Cotton Materials
Authors: K Gerling, LM Herrmann, C Salewski, M Wolf, P Müllerbade, D Siegel-Axe, HP Wendel, C Schlensak, M Avci-Adali, S Stoppelkam
Biomolecules, 2021;11(7):.
Species: Human
Sample Types: Cell Culture Supernates

IL-1beta augments TGF-beta inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics
Authors: S Zhang, Y Fan, L Qin, X Fang, C Zhang, J Yue, W Bai, G Wang, Z Chen, H Renz, C Skevaki, X Liu, M Xie
Respiratory Research, 2021;22(1):216.
Species: Human
Sample Types: Sputum

Protein-Bound Uremic Toxins Induce Reactive Oxygen Species-Dependent and Inflammasome-Mediated IL-1beta Production in Kidney Proximal Tubule Cells
Authors: M Mihajlovic, MM Krebber, Y Yang, S Ahmed, V Lozovanu, D Andreeva, MC Verhaar, R Masereeuw
Biomedicines, 2021;9(10):.
Species: Human
Sample Types: Cell Culture Supernates

The influence of the gut microbiome on BCG-induced trained immunity
Authors: M Stražar, VP Mourits, VACM Koeken, LCJ de Bree, SJCFM Moorlag, LAB Joosten, R van Crevel, H Vlamakis, MG Netea, RJ Xavier
Genome Biology, 2021;22(1):275.
Species: Human
Sample Types: Cell Culture Supernates

The effect of moderate wine consumption on cytokine secretion by peripheral blood mononuclear cells: A randomized clinical study in coronary heart disease patients
Authors: E Fragopoulo, C Argyrou, M Detopoulou, S Tsitsou, S Seremeti, M Yannakouli, S Antonopoul, G Kolovou, P Kalogeropo
Cytokine, 2021;146(0):155629.
Species: Human
Sample Types: Cell Culture Supernates

Plasma markers in pulmonary hypertension subgroups correlate with patient survival
Authors: T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars
Respiratory Research, 2021;22(1):137.
Species: Human
Sample Types: Plasma

"Plurethosome" as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation
Authors: M Sguizzato, F Ferrara, P Mariani, A Pepe, R Cortesi, N Huang, F Simelière, P Boldrini, A Baldissero, G Valacchi, E Esposito
Pharmaceutics, 2021;13(8):.
Species: Human
Sample Types: Cell Culture Supernates

IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming
Authors: N Niu, J Yao, RC Bast, AK Sood, J Liu
Oncogenesis, 2021;10(9):65.
Species: Human
Sample Types: Cell Culture Supernates

Polyphenol-rich extract and fractions of Terminalia phaeocarpa Eichler possess hypoglycemic effect, reduce the release of cytokines, and inhibit lipase, &alpha-glucosidase, and &alpha-amilase enzymes
Authors: JHS Gomes, UC Mbiakop, RL Oliveira, JR Stehmann, RM Pádua, SF Cortes, FC Braga
Journal of ethnopharmacology, 2021;271(0):113847.
Species: Human
Sample Types: Cell Culture Supernates

Interleukin-1&alpha Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation
Authors: K Bernau, JP Leet, H Floerke, EM Bruhn, AL Noll, IS McDermott, S Esnault, NN Jarjour, N Sandbo
Cells, 2021;10(3):.
Species: Human
Sample Types: BALF

Timing of Tributyrin Supplementation Differentially Modulates Gastrointestinal Inflammation and Gut Microbial Recolonization Following Murine Ileocecal Resection
Authors: V Mocanu, H Park, J Dang, N Hotte, A Thiesen, M Laffin, H Wang, D Birch, K Madsen
Nutrients, 2021;13(6):.
Species: Mouse
Sample Types: Tissue Homogenates

Neutrophil extracellular trap clearance by synovial macrophages in gout
Authors: JH Jeong, SJ Choi, SM Ahn, JS Oh, YG Kim, CK Lee, B Yoo, S Hong
Arthritis Research & Therapy, 2021;23(1):88.
Species: Human
Sample Types: Cell Culture Supernates

Itaconate confers tolerance to late NLRP3 inflammasome activation
Authors: M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov
Cell Reports, 2021;34(10):108756.
Species: Human
Sample Types: Cell Culture Supernates

Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
Authors: K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner
Cell Reports, 2021;34(10):108826.
Species: Human
Sample Types: Cell Culture Supernates

Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae
Authors: AD Brunaugh, H Seo, Z Warnken, L Ding, SH Seo, HDC Smyth
PLoS ONE, 2021;16(2):e0246803.
Species: Human
Sample Types: Cell Culture Supernates

Anti-inflammatory activity of soluble chito-oligosaccharides (CHOS) on VitD3-induced human THP-1 monocytes
Authors: P Jitprasert, M Khamphio, P Petsrichua, VGH Eijsink, W Poolsri, C Muanprasat, K Rangnoi, M Yamabhai
PLoS ONE, 2021;16(2):e0246381.
Species: Human
Sample Types: Cell Culture Supernates

Associations between salivary cytokines and periodontal and microbiological parameters in orthodontic patients
Authors: Y Chen, WK Wong, JC Seneviratn, S Huang, C McGrath, U Hagg
Medicine, 2021;100(10):e24924.
Species: Human
Sample Types: Saliva

Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response
Authors: MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad
Cell Death & Disease, 2021;12(3):241.
Species: Human
Sample Types: Cell Culture Supernates

IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
Authors: R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, S Parameswar, C Liang, C Arana, B Zhang, B Wakeland, J Zhou, MT Weirauch, LC Kottyan, EK Wakeland, C Pasare
Cell Reports, 2021;34(12):108891.
Species: Human
Sample Types: Cell Culture Supernates

Lipopolysaccharide stimulation test on cultured PBMCs assists the discrimination of cryopyrin-associated periodic syndrome from systemic juvenile idiopathic arthritis
Authors: CY Wu, WL Fan, YM Chiu, HY Yang, WI Lee, JL Huang
Scientific Reports, 2021;11(1):11903.
Species: Human
Sample Types: Cell Culture Supernates

Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells
Authors: C Panda, C Voelz, P Habib, C Mevissen, T Pufe, C Beyer, S Gupta, A Slowik
Cells, 2021;10(7):.
Species: Human
Sample Types: Cell Culture Supernates

Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
Cell Reports, 2021;36(12):109726.
Species: Human
Sample Types: Cell Culture Supernates

Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production
Authors: YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang
Arthritis Research & Therapy, 2021;23(1):171.
Species: Human
Sample Types: Cell Culture Supernates

Differential recognition of HIV-stimulated IL-1&beta and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages
Authors: K Triantafil, CJK Ward, M Czubala, RG Ferris, E Koppe, C Haffner, V Piguet, VK Patel, H Amrine-Mad, L Modis, SL Masters, M Triantafil
PloS Pathogens, 2021;17(4):e1009417.
Species: Human
Sample Types: Cell Culture Supernates

Sintered S53P4 bioactive glass scaffolds have anti-inflammatory properties and stimulate osteogenesis in vitro
Authors: R Björkenhei, E Jämsen, E Eriksson, P Uppstu, L Aalto-Setä, L Hupa, KK Eklund, M Ainola, NC Lindfors, J Pajarinen
European cells & materials, 2021;41(0):15-30.
Species: Human
Sample Types: Cell Culture Supernates

Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets
Authors: SH Kim, SH Hong, JH Lee, DH Lee, K Jung, JY Yang, HS Shin, J Lee, J Jeong, JH Oh
Toxics, 2021;9(3):.
Species: Human
Sample Types: cell culture supernatant

An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles
Authors: M Busch, AAM Kämpfer, RPF Schins
Chemosphere, 2021;284(0):131345.
Species: Human
Sample Types: Cell Culture Supernates

Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis
Authors: H Bonnekoh, C Vera, A Abad-Perez, S Radetzki, M Neuenschwa, E Specker, NA Mahnke, S Frischbutt, E Latz, M Nazaré, JV Kries, M Maurer, J Scheffel, K Krause
Clinical and translational allergy, 2021;11(5):e12045.
Species: Human
Sample Types: Tissue Homogenates

Structural Deformation of MTX Induced by Nanodrug Conjugation Dictate Intracellular Drug Transport and Drug Efficacy
Authors: JY Park, JS Hyun, JG Jee, SJ Park, D Khang
International Journal of Nanomedicine, 2021;16(0):4943-4957.
Species: Human
Sample Types: Cell Culture Supernates

Proteopathic tau primes and activates interleukin-1beta via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
Authors: S Jiang, NM Maphis, J Binder, D Chisholm, L Weston, W Duran, C Peterson, A Zimmerman, MA Mandell, SD Jett, E Bigio, C Geula, N Mellios, JP Weick, GA Rosenberg, E Latz, MT Heneka, K Bhaskar
Cell Reports, 2021;36(12):109720.
Species: Human
Sample Types: Tissue Homogenates

Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit
Authors: T Katopodi, S Petanidis, K Domvri, P Zarogoulid, D Anestakis, C Charalampi, D Tsavlis, C Bai, H Huang, L Freitag, W Hohenforst, D Matthaios, K Porpodis
Scientific Reports, 2021;11(1):15455.
Species: Human
Sample Types: Cell Culture Supernates

A prospective cohort study providing insights for markers of adverse pregnancy outcome in older mothers
Authors: SC Lean, RL Jones, SA Roberts, AEP Heazell
BMC pregnancy and childbirth, 2021;21(1):706.
Species: Human
Sample Types: Serum

COVID-19 Modulates Inflammatory and Renal Markers That May Predict Hospital Outcomes among African American Males
Authors: W Fonseca, N Asai, K Yagi, CA Malinczak, G Savickas, CC Johnson, S Murray, EM Zoratti, NW Lukacs, J Li, CF Schuler Iv
Viruses, 2021;13(12):.
Species: Human
Sample Types: Whole Blood

Decreased microRNA-155 in Behcet's disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production
Authors: L Liang, Q Zhou, L Feng
Arthritis Research & Therapy, 2021;23(1):135.
Species: Human
Sample Types: Cell Culture Supernates

Psychological symptoms and salivary inflammatory biomarkers in patients with dentofacial deformities: a case-control study
Authors: MCC Volkweis, GW Neculqueo, RDS Freitas, APA Dagnino, GG Fritscher, TQ Irigaray, MM Campos
Scientific Reports, 2021;11(1):11083.
Species: Human
Sample Types: Saliva

Attenuation of High Glucose-Induced Damage in RPE Cells through p38 MAPK Signaling Pathway Inhibition
Authors: G Maugeri, C Bucolo, F Drago, S Rossi, M Di Rosa, R Imbesi, V D'Agata, S Giunta
Frontiers in Pharmacology, 2021;12(0):684680.
Species: Human
Sample Types: Cell Culture Supernates

Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis
Authors: S Schlichtne, NH Meyer, IM Yasinska, N Aliu, SM Berger, BF Gibbs, E Fasler-Kan, VV Sumbayev
International immunopharmacology, 2021;100(0):108155.
Species: Human
Sample Types: Cell Culture Supernates

Parabens disrupt non-canonical inflammasome activation
Authors: H Ahn, H Lee, G Lee, J Park, HW Sung, E Lee, GS Lee
International immunopharmacology, 2021;101(0):108196.
Species: Mouse
Sample Types: Cell Culture Supernates

Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis
Authors: X Zhu, Y Zhan, Y Gu, Q Huang, T Wang, Z Deng, J Xie
Frontiers in Physiology, 2021;12(0):733650.
Species: Human
Sample Types: Cell Culture Supernates

Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled phase 2 trial
Authors: V Mocanu, Z Zhang, EC Deehan, DH Kao, N Hotte, S Karmali, DW Birch, KK Samarasing, J Walter, KL Madsen
Nature Medicine, 2021;27(7):1272-1279.
Species: Human
Sample Types: Serum

In Vitro Priming of Human T Cells by Dendritic Cells Provides a Screening Tool for Candidate Vaccines for Burkholderia pseudomallei
Authors: D Reddi, L Durant, D Bernardo, A Noble, NR English, P Hendy, GC Clark, JL Prior, ED Williamson, SC Knight
Vaccines, 2021;9(8):.
Species: Human
Sample Types: Cell Culture Supernates

Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner
Authors: W Zhang, G Yin, H Zhao, H Ling, Z Xie, C Xiao, Y Chen, Y Lin, T Jiang, S Jin, J Wang, X Yang
Cell Death & Disease, 2021;12(1):102.
Species: Human
Sample Types: Serum

Propionibacterium acnes Accelerates Intervertebral Disc Degeneration by Inducing Pyroptosis of Nucleus Pulposus Cells via the ROS-NLRP3 Pathway
Authors: G Tang, X Han, Z Lin, H Qian, B Chen, C Zhou, Y Chen, W Jiang
Oxidative Medicine and Cellular Longevity, 2021;2021(0):4657014.
Species: Human
Sample Types: Cell Culture Supernates

Differential Regulation of Circulating Soluble Receptor for Advanced Glycation End Products (sRAGEs) and Its Ligands S100A8/A9 Four Weeks Post an Exercise Intervention in a Cohort of Young Army Recruits
Authors: IA Drosatos, JN Tsoporis, S Izhar, S Gupta, G Tsirebolos, E Sakadakis, AS Triantafyl, A Rigopoulos, D Rigopoulos, LS Rallidis, I Rizos, TG Parker
Biomolecules, 2021;11(9):.
Species: Human
Sample Types: Plasma

Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages
Authors: X Ding, H Kambara, R Guo, A Kanneganti, M Acosta-Zal, J Li, F Liu, T Bei, W Qi, X Xie, W Han, N Liu, C Zhang, X Zhang, H Yu, L Zhao, F Ma, JR Köhler, HR Luo
Nature Communications, 2021;12(1):6699.
Species: Human
Sample Types: Cell Culture Supernates

Inflammatory responses to metal oxide ceramic nanopowders
Authors: S Jamieson, A Mawdesley, D Deehan, J Kirby, J Holland, A Tyson-Capp
Scientific Reports, 2021;11(1):10531.
Species: Human
Sample Types: Cell Culture Supernates

HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
Authors: L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang
Autophagy, 2021;0(0):1-20.
Species: Rat
Sample Types: Serum

Skin Substitute Preparation Method Induces Immunomodulatory Changes in Co-Incubated Cells through Collagen Modification
Authors: J Holl, C Pawlukiani, J Corton Rui, D Groth, K Grubczak, HR Hady, J Dadan, J Reszec, S Czaban, C Kowalewski, M Moniuszko, A Eljaszewic
Pharmaceutics, 2021;13(12):.
Species: Human
Sample Types: Cell Culture Supernates

Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures
Authors: JW Kennedy, PM Tsimbouri, P Campsie, S Sood, PG Childs, S Reid, PS Young, DRM Meek, CS Goodyear, MJ Dalby
Scientific Reports, 2021;11(1):22741.
Species: Human
Sample Types: Cell Culture Supernates

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
Authors: MC Kiritsy, K McCann, D Mott, SM Holland, SM Behar, CM Sassetti, AJ Olive
Elife, 2021;10(0):.
Species: Human
Sample Types: Cell Culture Supernates

The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection
Authors: QT Phan, J Lin, NV Solis, M Eng, M Swidergall, F Wang, S Li, SL Gaffen, TF Chou, SG Filler
MBio, 2021;0(0):e0271621.
Species: Human
Sample Types: Cell Culture Supernates

An observational study of innate immune responses in patients with acute appendicitis
Authors: T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens
Sci Rep, 2020;10(1):17352.
Species: Human
Sample Types: Cell Culture Supernates

Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease
Authors: X Zhang, R Wang, D Hu, X Sun, H Fujioka, K Lundberg, ER Chan, Q Wang, R Xu, ME Flanagan, AA Pieper, X Qi
Science Advances, 2020;6(49):.
Species: Human
Sample Types: Cell Culture Supernates

Cerebrospinal fluid of chronic osteoarthritic patients induced interleukin-6 release in human glial cell-line T98G
Authors: W Liu, C Li, FCK Tan, HJ Neo, YH Chan, CM Low, TL Lee
BMC Anesthesiol, 2020;20(1):69.
Species: Human
Sample Types: Cell Culture Supernates

Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells
Authors: V Panagiotak, D Ivanyuk, S De Cicco, W Haq, A Arsi?, C Yu, D Messelodi, M Oldrati, DC Schöndorf, MJ Perez, RP Cassatella, M Jakobi, N Schneiderh, T Gasser, I Niki?-Spie, M Deleidi
Nat Commun, 2020;11(1):5163.
Species: Human
Sample Types: Whole Cells

Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
PLoS Pathog., 2020;16(8):e1008781.
Species: Human
Sample Types: Cell Culture Supernates

Amyloid Beta Peptide (A&beta1-42) Reverses the Cholinergic Control of Monocytic IL-1&beta Release
Authors: K Richter, R Ogiemwonyi, S Wilker, AI Chaveiro, A Agné, M Hecker, M Reichert, AL Amati, KD Schlüter, I Manzini, G Schmalzing, JM McIntosh, W Padberg, V Grau, A Hecker
J Clin Med, 2020;9(9):.
Species: Human
Sample Types: Cell Culture Supernates

Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles
Authors: C Pavan, R Santalucia, R Leinardi, M Fabbiani, Y Yakoub, F Uwambayine, P Ugliengo, M Tomatis, G Martra, F Turci, D Lison, B Fubini
Proc Natl Acad Sci U S A, 2020;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

A new cytokine-based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia
Authors: P Peterlin, J Gaschet, T Guillaume, A Garnier, M Eveillard, A Le Bourgeo, M Cherel, C Debord, Y Le Bris, O Theisen, C Godon, B Mahé, V Dubruille, S Wuilleme, C Touzeau, T Gastinne, N Blin, A Lok, B Tessoulin, S Le Gouill, P Moreau, MC Béné, P Chevallier
Cancer Medicine, 2020;0(0):.
Species: Human
Sample Types: Serum

Vibration synergistically enhances IL-1&beta and TNF-&alpha in compressed human periodontal ligament cells in the frequency-dependent manner
Authors: S Benjakul, B Unat, P Thammanich, C Leethanaku
J Oral Biol Craniofac Res, 2020;10(4):412-416.
Species: Human
Sample Types: Cell Culture Supernates

The non-saponin fraction of Korean Red Ginseng (KGC05P0) decreases glucose uptake and transport in�vitro and modulates glucose production via down-regulation of the PI3K/AKT pathway in�vivo
Authors: SJ Park, D Lee, D Kim, M Lee, G In, ST Han, SW Kim, MH Lee, OK Kim, J Lee
J Ginseng Res, 2020;44(2):362-372.
Species: Human
Sample Types: Serum

Differentially Expressed Genes of Natural Killer Cells Can Distinguish Rheumatoid Arthritis Patients from Healthy Controls
Authors: NM Elemam, MY Hachim, S Hannawi, AA Maghazachi
Genes (Basel), 2020;11(5):.
Species: Human
Sample Types: Plasma

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids
Authors: MJ Pérez, D Ivanyuk, V Panagiotak, G Di Napoli, S Kalb, D Brunetti, R Al-Shaana, SA Kaeser, SA Fraschka, M Jucker, M Zeviani, C Viscomi, M Deleidi
Mol. Psychiatry, 2020;0(0):.
Species: Human
Sample Types: Cell Culture Lysates

Reprogramming of profibrotic macrophages for treatment of bleomycin-induced pulmonary fibrosis
Authors: F Zhang, EA Ayaub, B Wang, E Puchulu-Ca, YH Li, SU Hettiarach, SD Lindeman, Q Luo, S Rout, M Srinivasar, A Cox, K Tsoyi, C Nickerson-, IO Rosas, PS Low
EMBO Mol Med, 2020;0(0):e12034.
Species: Human
Sample Types: Cell Culture Supernates

MG53 suppresses interferon-&beta and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
Authors: M Sermershei, AD Kenney, PH Lin, TM McMichael, C Cai, K Gumpper, TMA Adesanya, H Li, X Zhou, KH Park, JS Yount, J Ma
Nat Commun, 2020;11(1):3624.
Species: Human
Sample Types: Cell Culture Supernates

PB1-F2 protein of highly pathogenic influenza A (H7N9) virus selectively suppresses RNA-induced NLRP3 inflammasome activation through inhibition of MAVS-NLRP3 interaction
Authors: PH Cheung, ZW Ye, TT Lee, H Chen, CP Chan, DY Jin
J. Leukoc. Biol., 2020;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Pro-inflammatory properties of H-ferritin on human macrophages, ex vivo and in vitro observations
Authors: P Ruscitti, P Di Benedet, O Berardicur, N Panzera, N Grazia, AR Lizzi, P Cipriani, Y Shoenfeld, R Giacomelli
Sci Rep, 2020;10(1):12232.
Species: Human
Sample Types: Cell Culture Supernates

Cigarette smoke and extracellular Hsp70 induce secretion of ATP and differential activation of NLRP3 inflammasome in monocytic and bronchial epithelial cells
Authors: L Rumora, A Somborac-B, I Hlap?i?, A Hulina-Tom, MG Rajkovi?
Cytokine, 2020;135(0):155220.
Species: Human
Sample Types: Cell Culture Supernates

Activation of Human &gamma&delta T Cells: Modulation by Toll-Like Receptor 8 Ligands and Role of Monocytes
Authors: R Serrano, D Wesch, D Kabelitz
Cells, 2020;9(3):.
Species: Human
Sample Types: Cell Culture Supernates

Recombinant Alkaline Phosphatase Prevents Acute on Chronic Liver Failure
Authors: C Engelmann, D Adebayo, M Oria, F De Chiara, S Novelli, A Habtesion, N Davies, F Andreola, R Jalan
Sci Rep, 2020;10(1):389.
Species: Human
Sample Types: Cell Culture Supernates

N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
Nat Commun, 2020;11(1):2212.
Species: Human
Sample Types: Cell Culture Supernates

Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21
Authors: L Mercurio, D Lulli, F Mascia, E Dellambra, C Scarponi, M Morelli, C Valente, ML Carbone, S Pallotta, G Girolomoni, C Albanesi, S Pastore, S Madonna
Aging (Albany NY), 2020;12(8):6823-6851.
Species: Human
Sample Types: Cell Culture Supernates

Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-&lambda3 or IFN-&lambda4 show distinct phenotypes
Authors: M De, A Bhushan, S Chinnaswam
J Leukoc Biol, 2020;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells
Authors: VM Abrahams, Z Tang, G Mor, S Guller
J Reprod Immunol, 2020;142(0):103214.
Species: Human
Sample Types: Cell Culture Supernates

Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma
Authors: Z Zhai, JM Samson, T Yamauchi, PK Vaddi, Y Matsumoto, CA Dinarello, D Ravindran, M Fujita
Cancers (Basel), 2020;12(9):.
Species: Human
Sample Types: Cell Culture Supernates

Modified citrus pectins by UV/H2O2 oxidation at acidic and basic conditions: Structures and in vitro anti-inflammatory, anti-proliferative activities
Authors: J Cao, J Yang, Z Wang, M Lu, K Yue
Carbohydr Polym, 2020;247(0):116742.
Species: Human
Sample Types: Cell Culture Supernates

Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages
Authors: LJ Williams, SG Tristram, GR Zosky
International Journal of Environmental Research and Public Health, 2020;18(1):.
Species: Human
Sample Types: Cell Culture Supernates

BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils
Authors: SJCFM Moorlag, YA Rodriguez-, J Gillard, S Fanucchi, K Theunissen, B Novakovic, CM de Bont, Y Negishi, ET Fok, L Kalafati, P Verginis, VP Mourits, VACM Koeken, LCJ de Bree, GJM Pruijn, C Fenwick, R van Crevel, LAB Joosten, I Joosten, H Koenen, MM Mhlanga, DA Diavatopou, T Chavakis, MG Netea
Cell Rep, 2020;33(7):108387.
Species: Human
Sample Types: Cell Culture Supernates

Who Is Afraid of CRP? Elevated Preoperative CRP Levels Might Attenuate the Increase in Inflammatory Parameters in Response to Lung Cancer Surgery
Authors: MM Meyer, L Brandenbur, H Hudel, A Agné, W Padberg, A Erdogan, H Nef, AL Amati, O Dörr, B Witte, V Grau
J Clin Med, 2020;9(10):.
Species: Human
Sample Types: Cell Culture Supernates

Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion
Authors: M Estermann, YL Huang, D Septiadi, D Ritz, CY Liang, F Jacob, B Drasler, A Petri-Fink, V Heinzelman, B Rothen-Rut
PLoS ONE, 2020;15(12):e0241500.
Species: Human
Sample Types: Abdominal Fluid

Clinical Response to the CD95-Ligand Inhibitor Asunercept Is Defined by a Pro-Inflammatory Serum Cytokine Profile
Authors: A Radujkovic, T Boch, F Nolte, D Nowak, C Kunz, A Gieffers, C Müller-Tid, P Dreger, WK Hofmann, T Luft
Cancers, 2020;12(12):.
Species: Human
Sample Types: Serum

Oral Lactobacillus strains reduce cytotoxicity and cytokine release from peripheral blood mononuclear cells exposed to Aggregatibacter actinomycetemcomitans subtypes in vitro
Authors: N Pahumunto, A Basic, AK Östberg, R Teanpaisan, G Dahlen
BMC Microbiol., 2020;20(1):279.
Species: Human
Sample Types: Cell Culture Supernates

Protective effect of bromfenac sodium on femtosecond laser?assisted cataract surgery via modulating cyclooxygenase?2 expression
Authors: L Lu, J Zhao, J Wang, Y Qin, J Zhang
Mol Med Rep, 2020;22(3):2433-2441.
Species: Human
Sample Types: Cell Culture Supernates

Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
Authors: PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz
Cell Rep, 2020;33(2):108247.
Species: Mouse
Sample Types: Cell Culture Supernates

Pancreatic cancer-derived small extracellular vesical Ezrin regulates macrophage polarization and promotes metastasis
Authors: YT Chang, HY Peng, CM Hu, SC Huang, SC Tien, YM Jeng
Am J Cancer Res, 2020;10(1):12-37.
Species: Human
Sample Types: Cell Culture Supernates

Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
PLoS Pathog., 2020;16(8):e1008781.
Species: Human
Sample Types: Cell Culture Supernates

Sex Differences in Proatherogenic Cytokine Levels
Authors: S Bernardi, B Toffoli, F Tonon, M Francica, E Campagnolo, T Ferretti, S Comar, F Giudici, E Stenner, B Fabris
Int J Mol Sci, 2020;21(11):.
Species: Human
Sample Types:

Scrodentoids H and I, a Pair of Natural Epimerides from Scrophularia dentata, Inhibit Inflammation through JNK-STAT3 Axis in THP-1 Cells
Authors: G Mao, L Sun, J Xu, Y Li, C Dunzhu, L Zhang, F Qian
Evid Based Complement Alternat Med, 2020;2020(0):1842347.
Species: Human
Sample Types: Cell Culture Supernates

Salivary Biomarkers of Oral Inflammation Are Associated With Cardiovascular Events and Death Among Kidney Transplant Patients
Authors: F Ortiz, KM Nylund, H Ruokonen, JH Meurman, J Furuholm, N Bostanci, T Sorsa
Transplant. Proc., 2020;0(0):.
Species: Human
Sample Types: Saliva

Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-kappaB and PI3K-Akt signaling networks
Authors: MA Haque, I Jantan, H Harikrishn, W Ahmad
BMC Complement Med Ther, 2020;20(1):245.
Species: Human
Sample Types: Cell Culture Supernates

SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
medRxiv : the preprint server for health sciences, 2020;0(0):.
Species: Human
Sample Types: Fecal Supernates

ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes
Authors: S Niklander, D Bandaru, DW Lambert, KD Hunter
FEBS Open Bio, 2020;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Vibration synergistically enhances IL-1beta and TNF-alpha in compressed human periodontal ligament cells in the frequency-dependent manner
Authors: S Benjakul, B Unat, P Thammanich, C Leethanaku
J Oral Biol Craniofac Res, 2020;10(4):412-416.
Species: Human
Sample Types: Cell Culture Supernates

Modified citrus pectins by UV/H2O2 oxidation at acidic and basic conditions: Structures and in vitro anti-inflammatory, anti-proliferative activities
Authors: J Cao, J Yang, Z Wang, M Lu, K Yue
Carbohydr Polym, 2020;247(0):116742.
Species: Human
Sample Types: Cell Culture Supernates

Modeling HIV-1 neuropathogenesis using three-dimensional human brain organoids (hBORGs) with HIV-1 infected microglia
Authors: RS Dos Reis, S Sant, H Keeney, MCE Wagner, V Ayyavoo
Scientific Reports, 2020;10(1):15209.
Species: Human
Sample Types: Organoid

Inflammasome-Driven Interleukin-1α and�Interleukin-1? Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity
Authors: X Jiang, F Wang, Y Wang, A Gisterå, J Roy, G Paulsson-B, U Hedin, A Lerman, GK Hansson, J Herrmann, ZQ Yan
JACC Basic Transl Sci, 2019;4(3):304-317.
Species: Human
Sample Types: Tissue Culture Supernates

Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16
Authors: M Ma, CM Percopo, DE Sturdevant, AC Sek, HD Komarow, HF Rosenberg
J. Immunol., 2019;0(0):.
Species: Human
Sample Types: Cell Lysates

EASIX for prediction of survival in lower-risk myelodysplastic syndromes
Authors: A Merz, U Germing, G Kobbe, J Kaivers, A Jauch, A Radujkovic, M Hummel, A Benner, M Merz, P Dreger, T Luft
Blood Cancer J, 2019;9(11):85.
Species: Human
Sample Types: Plasma

Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
Invest. Ophthalmol. Vis. Sci., 2019;60(14):4820-4829.
Species: Human
Sample Types: Cell Culture Supernates

Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
MBio, 2019;10(5):.
Species: Human
Sample Types: Cell Culture Supernates

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32
Authors: JC Dos Santos, AM Barroso de, MV Teodoro Si, B Cirovic, LCJ de Bree, MSMA Damen, SJCFM Moorlag, RS Gomes, MM Helsen, M Oosting, ST Keating, A Schlitzer, MG Netea, F Ribeiro-Di, LAB Joosten
Cell Rep, 2019;28(10):2659-2672.e6.
Species: Human
Sample Types: Cell Culture Supernates

Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
Authors: S Dogra, M Wolf, MP Jeffrey, RCA Foley, H Logan-Spre, H Jones-Tagg, JM Green-John
BMC Sports Sci Med Rehabil, 2019;11(0):23.
Species: Human
Sample Types: Saliva

IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin
Authors: I Tsilioni, AB Patel, H Pantazopou, S Berretta, P Conti, SE Leeman, TC Theoharide
Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages
Authors: C Jumeau, F Awad, E Assrawi, L Cobret, P Duquesnoy, I Giurgea, D Valeyre, G Grateau, S Amselem, JF Bernaudin, SA Karabina
PLoS ONE, 2019;14(5):e0217005.
Species: Human
Sample Types: Cell Culture Supernates

Physiologic intestinal 18F-FDG uptake is associated with alteration of gut microbiota and proinflammatory cytokine levels in breast cancer
Authors: HJ Yoon, HN Kim, JI Bang, W Lim, BI Moon, NS Paik, BS Kim, HL Kim
Sci Rep, 2019;9(1):18273.
Species: Human
Sample Types: Serum

Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells
Authors: R Saga, K Hasegawa, K Murata, M Chiba, T Nakamura, K Okumura, E Tsuruga, Y Hosokawa
Oncol Lett, 2019;17(3):3555-3561.
Species: Human
Sample Types: Cell Culture Supernates

Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages
Authors: PJ Goddard, J Sanchez-Ga, SL Slater, M Kalyan, D Ruano-Gall, O Marchès, LÁ Fernández, G Frankel, AR Shenoy
Cell Rep, 2019;27(4):1008-1017.e6.
Species: Human
Sample Types: Cell Culture Supernates

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
PLoS Pathog., 2019;15(4):e1007689.
Species: Human
Sample Types: Cell Culture Supernates

Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
Authors: C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong
Mol. Cancer, 2019;18(1):64.
Species: Human
Sample Types: Cell Culture Supernates

Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis
Authors: L Su, P Pan, P Yan, Y Long, X Zhou, X Wang, R Zhou, B Wen, L Xie, D Liu
Sci Rep, 2019;9(1):5747.
Species: Human
Sample Types: Cell Culture Supernates

The effect of compressive force combined with mechanical vibration on human alveolar bone osteoblasts
Authors: C Chatmahamo, A Pravithara, S Suttapreya, C Leethanaku
J Oral Biol Craniofac Res, 2019;9(1):81-85.
Species: Human
Sample Types: Cell Culture Supernates

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans
Authors: E Kaasinen, O Kuismin, K Rajamäki, H Ristolaine, M Aavikko, J Kondelin, S Saarinen, DG Berta, R Katainen, EAM Hirvonen, A Karhu, A Taira, T Tanskanen, A Alkodsi, M Taipale, E Morgunova, K Franssila, R Lehtonen, M Mäkinen, K Aittomäki, A Palotie, MI Kurki, O Pietiläine, M Hilpert, E Saarentaus, J Niinimäki, J Junttila, K Kaikkonen, P Vahteristo, RC Skoda, MRJ Seppänen, KK Eklund, J Taipale, O Kilpivaara, LA Aaltonen
Nat Commun, 2019;10(1):1252.
Species: Human
Sample Types: Cell Culture Supernates

Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential
Authors: D Raghunatha, PM Radford, C Gell, D Negus, C Moore, R Till, PJ Tighe, SP Wheatley, L Martinez-P, RE Sockett, J Tyson
Sci Rep, 2019;9(1):4293.
Species: Human
Sample Types: Cell Culture Supernates

In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists
Authors: R Gramlich, E Aliahmadi, M Peiser
Int J Mol Sci, 2019;20(6):.
Species: Human
Sample Types: Cell Culture Supernates

Cervical cancer-instructed stromal fibroblasts enhance IL-23 expression in dendritic cells to support expansion of Th17 cells
Authors: B Walch-Rück, R Ströder, L Theobald, J Pahne-Zepp, S Hegde, YJ Kim, RM Bohle, I Juhasz-Bös, EF Solomayer, S Smola
Cancer Res., 2019;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
Nat Microbiol, 2019;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Phenotypic and functional stability of leukocytes from human peripheral blood samples: considerations for the design of immunological studies
Authors: A Navas, L Giraldo-Pa, MD Prieto, J Cabrera, MA Gómez
BMC Immunol., 2019;20(1):5.
Species: Human
Sample Types: Cell Culture Supernates

Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation
Authors: MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, AF McGettrick, CE Sutton, C Diskin, M Rooke, S Takahashi, S Sundararaj, MG Casarotto, JE Dahlstrom, EM Palsson-Mc, SC Corr, KHG Mills, RJS Preston, N Neamati, Y Xie, JB Baell, PG Board, LAJ O'Neill
Cell Rep, 2019;29(1):151-161.e5.
Species: Human
Sample Types: Cell Culture Supernates

Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages
Authors: T Karasawa, A Kawashima, F Usui-Kawan, S Watanabe, H Kimura, R Kamata, K Shirasuna, Y Koyama, A Sato-Tomit, T Matsuzaka, H Tomoda, SY Park, N Shibayama, H Shimano, T Kasahara, M Takahashi
Arterioscler. Thromb. Vasc. Biol., 2018;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages
Authors: AMV Murthy, MD Phan, KM Peters, NTK Nhu, RA Welch, GC Ulett, MA Schembri, MJ Sweet
Virulence, 2018;0(0):1-32.
Species: Human
Sample Types: Cell Culture Supernates

Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma
Authors: T Kubo, M Tsujiwaki, Y Hirohashi, T Tsukahara, T Kanaseki, M Nakatsugaw, T Hasegawa, T Torigoe
Lab. Invest., 2018;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Clinical predictors of liver fibrosis in patients with chronic hepatitis B virus infection from children to adults
Authors: JF Wu, SH Song, CS Lee, HL Chen, YH Ni, HY Hsu, TC Wu, MH Chang
J. Infect. Dis., 2018;0(0):.
Species: Human
Sample Types: Serum

Analysis of the association between Fc receptor family gene polymorphisms and ocular Beh�et's disease in Han Chinese
Authors: D Zhang, J Qin, L Li, G Su, G Huang, Q Cao, A Kijlstra, P Yang
Sci Rep, 2018;8(1):4850.
Species: Human
Sample Types: Cell Culture Supernates

Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
Authors: BA McKenzie, MK Mamik, LB Saito, R Boghozian, MC Monaco, EO Major, JQ Lu, WG Branton, C Power
Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
Eur Cell Mater, 2018;35(0):13-24.

The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models
Authors: RF Hamilton, Z Wu, S Mitra, A Holian
Int J Mol Sci, 2018;19(2):.
Species: Human
Sample Types: Cell Culture Supernates

Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
Authors: B Lagrange, S Benaoudia, P Wallet, F Magnotti, A Provost, F Michal, A Martin, F Di Lorenzo, BF Py, A Molinaro, T Henry
Nat Commun, 2018;9(1):242.
Species: Human
Sample Types: Cell Culture Supernates

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus
Authors: L Laencina, V Dubois, V Le Moigne, A Viljoen, L Majlessi, J Pritchard, A Bernut, L Piel, AL Roux, JL Gaillard, B Lombard, D Loew, EJ Rubin, R Brosch, L Kremer, JL Herrmann, F Girard-Mis
Proc. Natl. Acad. Sci. U.S.A., 2018;115(5):E1002-E1011.
Species: Human
Sample Types: Cell Culture Supernates

Vaccine antigens modulate the innate response of monocytes to Al(OH)3
Authors: S Kooijman, J Brummelman, CACM van Els, F Marino, AJR Heck, E van Riet, B Metz, GFA Kersten, JLA Pennings, HD Meiring
PLoS ONE, 2018;13(5):e0197885.
Species: Human
Sample Types: Cell Culture Supernates

Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis
Authors: R Narasimhan, R Coras, SB Rosenthal, SR Sweeney, A Lodi, S Tiziani, D Boyle, A Kavanaugh, M Guma
Arthritis Res. Ther., 2018;20(1):164.
Species: Human
Sample Types: Serum

Annexin A1, FPR2/ALX, and inflammatory cytokine expression in peritoneal endometriosis
Authors: LK Volpato, VV Horewicz, F Bobinski, DF Martins, AP Piovezan
J. Reprod. Immunol., 2018;129(0):30-35.
Species: Human
Sample Types: Peritoneal Fluid

CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
Oncol Lett, 2018;15(6):9075-9080.
Species: Human
Sample Types: Cell Culture Supernates

GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
Nat Commun, 2018;9(1):3686.
Species: Human
Sample Types: Cell Culture Supernates

TET-2 up-regulation is associated with the anti-inflammatory action of Vicenin-2
Authors: N Hassan, A Ali, C Withycombe, M Ahluwalia, RH Al-Nasseri, A Tonks, K Morris
Cytokine, 2018;108(0):37-42.
Species: Human
Sample Types: Cell Culture Supernates

Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism
Authors: G Arbore, EE West, J Rahman, G Le Friec, N Niyonzima, M Pirooznia, I Tunc, P Pavlidis, N Powell, Y Li, P Liu, A Servais, L Couzi, V Fremeaux-B, L Placais, A Ferraro, PR Walsh, D Kavanagh, B Afzali, P Lavender, HJ Lachmann, C Kemper
Nat Commun, 2018;9(1):4186.
Species: Human
Sample Types: Cell Culture Supernates

A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal
Authors: M Mastri, A Tracz, CR Lee, M Dolan, K Attwood, JG Christense, S Liu, JML Ebos
Cell Rep, 2018;25(13):3706-3720.e8.
Species: Human
Sample Types: Cell Culture Supernates

Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface
Authors: I Tomašek, CJ Horwell, C Bisig, DE Damby, P Comte, J Czerwinski, A Petri-Fink, MJD Clift, B Drasler, B Rothen-Rut
Environ. Pollut., 2018;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease
Authors: Q Zhang, H Li, S Hou, H Yu, G Su, B Deng, J Qi, C Zhou, A Kijlstra, P Yang
Br J Ophthalmol, 2018;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
Authors: LBS Hansen, HM Roager, NB Søndertoft, RJ Gøbel, M Kristensen, M Vallès-Col, S Vieira-Sil, S Ibrügger, MV Lind, RB Mærkedahl, MI Bahl, ML Madsen, J Havelund, G Falony, I Tetens, T Nielsen, KH Allin, HL Frandsen, B Hartmann, JJ Holst, MH Sparholt, J Holck, A Blennow, JM Moll, AS Meyer, C Hoppe, JH Poulsen, V Carvalho, D Sagnelli, MD Dalgaard, AF Christense, MC Lydolph, AB Ross, S Villas-Bôa, S Brix, T Sicheritz-, K Buschard, A Linneberg, JJ Rumessen, CT Ekstrøm, C Ritz, K Kristianse, HB Nielsen, H Vestergaar, NJ Færgeman, J Raes, H Frøkiær, T Hansen, L Lauritzen, R Gupta, TR Licht, O Pedersen
Nat Commun, 2018;9(1):4630.
Species: Human
Sample Types: Cell Culture Supernates

Combining Calcium Phosphates with Polysaccharides: A Bone-Inspired Material Modulating Monocyte/Macrophage Early Inflammatory Response
Authors: H Rammal, C Bour, M Dubus, L Entz, L Aubert, SC Gangloff, S Audonnet, NB Bercu, F Boulmedais, C Mauprivez, H Kerdjoudj
Int J Mol Sci, 2018;19(11):.
Species: Human
Sample Types: Cell Culture Supernates

A central role for P2X7 receptors in human microglia
Authors: L Janks, CVR Sharma, TM Egan
J Neuroinflammation, 2018;15(1):325.
Species: Human
Sample Types: Cell Culture Supernates

Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
Invest. Ophthalmol. Vis. Sci., 2018;59(2):1158-1166.
Species: Human
Sample Types: Cell Culture Supernates

PDGF enhances the protective effect of adipose stem cell-derived extracellular vesicles in a model of acute hindlimb ischemia
Authors: T Lopatina, E Favaro, C Grange, M Cedrino, A Ranghino, S Occhipinti, S Fallo, F Buffolo, DA Gaykalova, MM Zanone, R Romagnoli, G Camussi
Sci Rep, 2018;8(1):17458.
Species: Human
Sample Types: Cell Culture Supernates

The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1? by Human Cytomegalovirus through Inhibition of NF-kB Activity
Authors: M Biolatti, V Dell'Oste, S Scutera, F Gugliesi, G Griffante, M De Andrea, T Musso, S Landolfo
Viruses, 2018;10(10):.
Species: Human
Sample Types: Cell Culture Supernates

Sulphamethazine derivatives as immunomodulating agents: New therapeutic strategies for inflammatory diseases
Authors: H Siddiqui, HM Haniffa, A Jabeen, AU -Rahman, MI Choudhary
PLoS ONE, 2018;13(12):e0208933.
Species: Human
Sample Types: Cell Culture Supernates

S100B regulates inflammatory response during osteoarthritis via fibroblast growth factor receptor 1 signaling
Authors: L Zhu, Z Weng, P Shen, J Zhou, J Zeng, F Weng, X Zhang, H Yang
Mol Med Rep, 2018;18(6):4855-4864.
Species: Human
Sample Types: Cell Culture Supernates

Iron nanomedicines induce Toll-like receptor activation, cytokine production and complement activation
Authors: Johan J F Verhoef
Biomaterials, 2017;119(0):68-77.
Species: Human
Sample Types: Cell Culture Supernates

Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
Authors: L Chen, MS Eapen, GR Zosky
Sci Rep, 2017;7(0):45172.
Species: Human
Sample Types: Cell Culture Supernates

Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study
Authors: J Vandooren, S Knoops, JL Aldinucci, L Boon, E Martens, G Opdenakker, E Kolaczkows
PLoS ONE, 2017;12(4):e0174853.
Species: Human
Sample Types: Cell Culture Supernates

Rheumatoid arthritis bone marrow environment supports Th17 response
Authors: E Kuca-Warna, W Kurowska, M Prochorec-, A Radzikowsk, T Burakowski, U Skalska, M Massalska, M Pleba?czyk, B Ma?dyk-Now, I S?owi?ska, R Gasik, W Ma?li?ski
Arthritis Res. Ther., 2017;19(1):274.
Species: Human
Sample Types: Plasma

TB lymphadenitis is associated with enhanced baseline and antigen - specific induction of Type 1 and Type 17 cytokines and reduced IL-1? and IL-18 at the site of infection
Authors: GR Kathamuthu, K Moideen, D Baskaran, VV Banurekha, D Nair, G Sekar, R Sridhar, B Vidyajayan, G Gajendrara, DK Parandhama, A Srinivasan, S Babu
Clin. Vaccine Immunol, 2017;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response
Authors: S Das, M Raundhal, J Chen, TB Oriss, R Huff, JV Williams, A Ray, P Ray
JCI Insight, 2017;2(17):.
Species: Human
Sample Types: Cell Culture Supernates

Elevated CRP levels predict poor outcome and tumor recurrence in patients with thymic epithelial tumors: A pro- and retrospective analysis
Authors: S Janik, C Bekos, P Hacker, T Raunegger, B Ghanim, E Einwallner, L Beer, W Klepetko, L Müllauer, HJ Ankersmit, B Moser
Oncotarget, 2017;8(29):47090-47102.
Species: Human
Sample Types: Serum

Rheumatoid arthritis bone marrow environment supports Th17 response.
Authors: Ewa Kuca-Warna, Weronika Kurowska, Monika Prochorec, Anna Radzikows, Tomasz Burakowsk, Urszula Skalska, Magdalena Massalska, Magdalena Pleba?czy, Barbara Ma?dyk-No, Iwona S?owi?ska, Robert Gasik, W?odzimierz Ma?li?ski
Arthritis Research & Therapy, 2017;0(0):1478-6362.
Species: Human
Sample Types: Plasma

Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
Immun Ageing, 2017;14(0):5.
Species: Human
Sample Types: Cell Culture Supernates

Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF-? and IL-1? in third molar surgery: a triple-blind, randomized, placebo-controlled study
Authors: AFM Albuquerqu, CSR Fonteles, DR do Val, HV Chaves, MM Bezerra, KMA Pereira, PG de Barros, BB de Lima, ECS Soares, TR Ribeiro, FWG Costa
Int J Oral Maxillofac Surg, 2017;0(0):.
Species: Human
Sample Types: Tissue Homogenates

Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation
Authors: S Zwicker, E Hattinger, D Bureik, A Batycka-Ba, A Schmidt, PA Gerber, S Rothenfuss, M Gilliet, T Ruzicka, R Wolf
PLoS ONE, 2017;12(4):e0175153.
Species: Human
Sample Types: Cell Culture Supernates

In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens
Authors: N Goli?, K Veljovi?, N Popovi?, J Djoki?, I Strahini?, I Mrvaljevi?, A Terzi?-Vid
BMC Microbiol., 2017;17(1):108.
Species: Human
Sample Types: Cell Culture Supernates

Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
Sci Rep, 2017;7(1):1815.
Species: Human
Sample Types: Cell Culture Supernates

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT
Authors: S Dabo, P Maillard, M Collados R, MD Hansen, S Mazouz, DJ Bigot, M Tible, G Janvier, O Helynck, P Cassonnet, Y Jacob, J Bellalou, A Gatignol, RC Patel, J Hugon, H Munier-Leh, EF Meurs
Sci Rep, 2017;7(1):16129.
Species: Human
Sample Types: Cell Culture Supernates

Production and regulation of interleukin-1 family cytokines at the materno-fetal interface
Authors: LM Scott, AH Bryant, A Rees, B Down, RH Jones, CA Thornton
Cytokine, 2017;0(0):.
Species: Human
Sample Types: Tissue Culture Supernates

Altered distribution of peripheral blood dendritic cell subsets in patients with pulmonary paracoccidioidomycosis
Authors: J Venturini, RS Cavalcante, DV Moris, M de Assis G, AD Levorato, KH Dos Reis, MSP de Arruda, RP Mendes
Acta Trop., 2017;0(0):.
Species: Human
Sample Types: Serum

Induction of immune gene expression and inflammatory mediator release by commonly used surgical suture materials: an experimental in vitro study
Authors: AM Lock, R Gao, D Naot, B Coleman, J Cornish, DS Musson
Patient Saf Surg, 2017;11(0):16.
Species: Human
Sample Types: Cell Culture Supernates

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition
Authors: HL Young, EJ Rowling, M Bugatti, E Giurisato, N Luheshi, I Arozarena, JC Acosta, J Kamarashev, DT Frederick, ZA Cooper, A Reuben, J Gil, KT Flaherty, JA Wargo, W Vermi, MP Smith, C Wellbrock, A Hurlstone
J. Exp. Med., 2017;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

IL-18 associated with lung lymphoid aggregates drives IFN? production in severe COPD
Authors: E Briend, GJ Ferguson, M Mori, G Damera, K Stephenson, NA Karp, S Sethi, CK Ward, MA Sleeman, JS Erjefält, DK Finch
Respir. Res., 2017;18(1):159.
Species: Human
Sample Types: Cell Culture Supernates

In vitro effects of hyaluronic acid on human periodontal ligament cells
Authors: M Fujioka-Ko, HD Mller, A Mueller, A Lussi, A Sculean, PR Schmidlin, RJ Miron
BMC Oral Health, 2017;17(1):44.
Species: Human
Sample Types: Cell Culture Supernates

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
Authors: SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G N£¤ez, SL Masters, JM Murphy, K Schroder, DL Vaux, KE Lawlor, LM Lindqvist, JE Vince
Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?
Aging Cell, 2016;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
Sci Rep, 2016;6(0):39035.
Species: Human
Sample Types: Cell Culture Supernates

Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
J Leukoc Biol, 2016;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
PLoS ONE, 2016;11(4):e0153118.
Species: Human
Sample Types: Cell Culture Supernates

Receptor-Type Protein-Tyrosine Phosphatase ? and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1
PLoS ONE, 2016;11(11):e0167324.
Species: Human
Sample Types: Cell Culture Supernates

Reduced systemic and mycobacterial antigen-stimulated concentrations of IL-1? and IL-18 in tuberculous lymphadenitis
Cytokine, 2016;90(0):66-72.
Species: Human
Sample Types: Cell Culture Supernates

The Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes.
Authors: Simanski M, Rademacher F, Schroder L, Glaser R, Harder J
PLoS ONE, 2016;11(1):e0147118.
Species: Human
Sample Types: Cell Culture Supernates

Dental Calculus Stimulates Interleukin-1? Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes
Authors: JL Montenegro, A Yoshimura, Z Sm, T Kaneko, Y Ozaki, T Ukai, T Miyazaki, E Latz, Y Hara
PLoS ONE, 2016;11(9):e0162865.
Species: Human
Sample Types: Cell Culture Supernates

Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1? and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells
J Immunol, 2016;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum
J Immunol, 2016;0(0):.
Species: Human
Sample Types: Cell Culture Supernates

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
Authors: Avery D Posey
Immunity, 2016;44(6):1444-54.
Species: Human
Sample Types: Cell Culture Supernates

Interleukin-17A Induces IL-1? Secretion From RPE Cells Via the NLRP3 Inflammasome
Authors: S Zhang, N Yu, R Zhang, S Zhang, J Wu
Invest. Ophthalmol. Vis. Sci, 2016;57(2):312-9.
Species: Human
Sample Types: Cell Culture Supernates

CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection
PLoS Pathog, 2016;12(7):e1005770.
Species: Mouse
Sample Types: Cell Culture Supernates

Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
PLoS Pathog, 2016;12(9):e1005871.
Species: Human
Sample Types: Cell Culture Supernates

Combined exposure of diesel exhaust particles and respirable Soufri�re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
Authors: Ines Tomašek
Part Fibre Toxicol, 2016;13(1):67.
Species: Human
Sample Types: Cell Culture Supernates

17-oxo-DHA displays additive anti-inflammatory effects with fluticasone propionate and inhibits the NLRP3 inflammasome
Sci Rep, 2016;6(0):37625.
Species: Human
Sample Types: Cell Culture Supernates

Analysis of receptor tyrosine kinase genetics identifies two novel risk loci in GAS6 and PROS1 in Beh�et's disease
Sci Rep, 2016;6(0):26662.
Species: Human
Sample Types: Cell Culture Supernates

Graphene-augmented nanofiber scaffolds demonstrate new features in cells behaviour
Sci Rep, 2016;6(0):30150.
Species: Human
Sample Types: Cell Culture Supernates

Biocompatibility of primers and an adhesive used for implant-retained maxillofacial prostheses: An in�vitro analysis
Authors: Daniela Micheline Dos Santos
J Prosthet Dent, 2016;0(0):.

Modulating endotoxin activity by combinatorial bioengineering of meningococcal lipopolysaccharide
Sci Rep, 2016;6(0):36575.
Species: Human
Sample Types: Cell Culture Supernates

Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion
Authors: Mélissa Noack
Arthritis Res Ther, 2016;18(0):148.
Species: Human
Sample Types: Cell Culture Supernates

Silk-based blood stabilization for diagnostics
Proc Natl Acad Sci USA, 2016;113(21):5892-7.
Species: Human
Sample Types: Serum

Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
Sci Rep, 2016;6(0):24974.
Species: Human
Sample Types: Cell Culture Supernates

Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
Authors: Karmakar M, Katsnelson M, Malak H, Greene N, Howell S, Hise A, Camilli A, Kadioglu A, Dubyak G, Pearlman E
J Immunol, 2015;194(4):1763-75.
Species: Human
Sample Types: Cell Culture Supernates

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.
Authors: Antonopoulos C, Russo H, El Sanadi C, Martin B, Li X, Kaiser W, Mocarski E, Dubyak G
J Biol Chem, 2015;290(33):20167-84.
Species: Mouse
Sample Types: Cell Culture Supernates

LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease.
Authors: Broekman M, Roelofs H, Hoentjen F, Wiegertjes R, Stoel N, Joosten L, de Jong D, Wanten G
PLoS ONE, 2015;10(7):e0133932.
Species: Human
Sample Types: Plasma

Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.
Authors: Schupp J, Binder H, Jager B, Cillis G, Zissel G, Muller-Quernheim J, Prasse A
PLoS ONE, 2015;10(1):e0116775.
Species: Human
Sample Types: BALF

Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women.
Authors: McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K
PLoS ONE, 2015;10(8):e0134619.
Species: Human
Sample Types: Plasma

Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter.
Authors: Brand O, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson A, Hill A, Jablons D, Wolters P, Lou J, Marks J, Baron J, Nishimura S
J Biol Chem, 2015;290(23):14717-28.
Species: Human
Sample Types: Tissue Homogenates

In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
Reprod Biol Endocrinol, 2015;13(0):115.
Species: Human
Sample Types: Cell Culture Supernates

SRSF1 facilitates cytosolic DNA-induced production of type I interferons recognized by RIG-I.
Authors: Xue F, Li X, Zhao X, Wang L, Liu M, Shi R, Zheng J
PLoS ONE, 2015;10(2):e0115354.
Species: Human
Sample Types: Cell Culture Supernates

Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1beta, IFN-beta, and IL-15 Pathways.
Authors: Mattiola I, Pesant M, Tentorio P, Molgora M, Marcenaro E, Lugli E, Locati M, Mavilio D
J Immunol, 2015;195(6):2818-28.
Species: Human
Sample Types: Cell Culture Supernates

The effect of size on Ag nanosphere toxicity in macrophage cell models and lung epithelial cell lines is dependent on particle dissolution.
Authors: Hamilton, Raymond, Buckingham, Sarah, Holian, Andrij
Int J Mol Sci, 2014;15(4):6815-30.
Species: Human
Sample Types: Cell Culture Supernates

TLR ligands stimulation protects MSC from NK killing.
Authors: Giuliani M, Bennaceur-Griscelli A, Nanbakhsh A, Oudrhiri N, Chouaib S, Azzarone B, Durrbach A, Lataillade J
Stem Cells, 2014;32(1):290-300.
Species: Human
Sample Types: Cell Culture Supernates

A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
PLoS ONE, 2014;9(5):e96943.
Species: Human
Sample Types: Cell Culture Supernates

The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.
Authors: Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F
J Biol Chem, 2014;289(3):1364-76.

Residual endotoxin contaminations in recombinant proteins are sufficient to activate human CD1c+ dendritic cells.
Authors: Schwarz H, Schmittner M, Duschl A, Horejs-Hoeck J
PLoS ONE, 2014;9(12):e113840.
Species: Human
Sample Types: Cell Culture Supernates

Kineret(R)/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection.
Authors: Labrousse D, Perret M, Hayez D, da Silva S, Badiou C, Couzon F, Bes M, Chavanet P, Lina G, Vandenesch F, Croisier-Bertin D, Henry T
PLoS ONE, 2014;9(6):e97546.

Activin A as a mediator of NK-dendritic cell functional interactions.
Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
J Immunol, 2014;192(3):1241-8.
Species: Human
Sample Types: Cell Culture Supernates

Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
Authors: Zughaier, Susu M, Kandler, Justin L, Shafer, William
PLoS ONE, 2014;9(1):e87688.
Species: Human
Sample Types: Cell Culture Supernates

Angiopoietin-1 upregulates de novo expression of IL-1beta and Il1-Ra, and the exclusive release of Il1-Ra from human neutrophils.
Authors: Haddad L, Sirois M
PLoS ONE, 2014;9(2):e88980.
Species: Human
Sample Types: Cell Lysates

Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
J Biol Chem, 2014;289(27):19231-44.
Species: Human
Sample Types: Cell Culture Supernates

Integrin alphaDbeta2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.
Authors: Miyazaki Y, Vieira-de-Abreu A, Harris E, Shah A, Weyrich A, Castro-Faria-Neto H, Zimmerman G
PLoS ONE, 2014;9(11):e112770.
Species: Human
Sample Types: Cell Culture Supernates

Association of TLR2 gene polymorphisms with ocular Behcet's disease in a Chinese Han population.
Authors: Fang J, Hu R, Hou S, Ye Z, Xiang Q, Qi J, Zhou Y, Kijlstra A, Yang P
Invest Ophthalmol Vis Sci, 2013;54(13):8384-92.
Species: Human
Sample Types: Cell Culture Supernates

S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
PLoS ONE, 2013;8(4):e62372.

Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
PLoS ONE, 2013;8(12):e82734.
Species: Human
Sample Types: Cell Culture Supernates

Inflammasome induction in Rasmussen's encephalitis: cortical and associated white matter pathogenesis.
Authors: Ramaswamy V, Walsh J, Sinclair D, Johnson E, Tang-Wai R, Wheatley B, Branton W, Maingat F, Snyder T, Gross D, Power C
J Neuroinflammation, 2013;10(0):152.
Species: Human
Sample Types: Cell Culture Supernates

Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
Cytokine, 2013;65(2):222-30.
Species: Human
Sample Types: Cell Culture Supernates

Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
Authors: Suh HS, Choi N, Tarassishin L, Lee SC
PLoS ONE, 2012;7(4):e35115.
Species: Human
Sample Types: Cell Culture Supernates

Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
Eur J Clin Nutr, 2012;66(9):1072-4.
Species: Human
Sample Types: Serum

Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.
J. Exp. Med., 2012;209(8):1505-17.
Species: Human
Sample Types: Cell Culture Supernates

Monocytic microparticles activate endothelial cells in an IL-1{beta}-dependent manner.
Authors: Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N
Blood, 2011;118(8):2366-74.
Species: Human
Sample Types: Cell Lysates

Interleukin (IL)-31 induces pro-inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins.
Authors: Kasraie S, Niebuhr M, Werfel T
Allergy, 2010;65(6):712-21.
Species: Human
Sample Types: Cell Culture Supernates

Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
Authors: van de Veerdonk FL, Smeekens SP, Joosten LA, Kullberg BJ, Dinarello CA, Van der Meer JW, Netea MG
Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3030-3.
Species: Human
Sample Types: Cell Culture Supernates

Maternal IL-1beta production prevents lung injury in a mouse model of bronchopulmonary dysplasia.
Authors: Backstrom E, Lappalainen U, Bry K
Am. J. Respir. Cell Mol. Biol., 2010;42(2):149-60.
Species: Human
Sample Types: Tissue Homogenates

Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms.
Authors: Correale J, Farez M
J. Immunol., 2009;183(9):5999-6012.
Species: Human
Sample Types: Cell Culture Supernates

Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
Circulation, 2009;119(10):1424-32.
Species: Human
Sample Types: Plasma

Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia.
Authors: Lukkarinen H, Hogmalm A, Lappalainen U, Bry K
Am. J. Respir. Cell Mol. Biol., 2009;41(1):59-68.
Species: Human
Sample Types: Tissue Homogenates

The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages.
Authors: Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H
Eur. J. Immunol., 2009;39(3):820-5.
Species: Human
Sample Types: Cell Culture Supernates

TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
Eur. J. Immunol., 2009;39(5):1221-30.
Species: Human
Sample Types: Cell Culture Supernates

Divergent effects of hypoxia on dendritic cell functions.
Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A
Blood, 2008;112(9):3723-34.
Species: Human
Sample Types: Cell Culture Supernates

Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
J. Cell. Physiol., 2008;214(1):27-37.
Species: Human
Sample Types: Cell Culture Supernates

Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
J. Biol. Chem., 2007;282(44):31882-90.
Species: Human
Sample Types: Cell Culture Supernates

Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.
Authors: Duluc D, Delneste Y, Tan F, Moles MP, Grimaud L, Lenoir J, Preisser L, Anegon I, Catala L, Ifrah N, Descamps P, Gamelin E, Gascan H, Hebbar M, Jeannin P
Blood, 2007;110(13):4319-30.
Species: Human
Sample Types: Cell Culture Supernates

Early cytokine responses after percutaneous magnetic resonance imaging guided laser thermoablation of malignant liver tumors.
Authors: Kallio R, Sequeiros R, Surcel HM, Ohtonen P, Kiviniemi H, Syrjala H
Cytokine, 2007;34(5):278-83.
Species: Human
Sample Types: Serum

Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
J. Clin. Invest., 2007;117(12):3664-3672.
Species: Human
Sample Types: Cell Culture Supernates

Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis.
Authors: Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C
J. Immunol., 2007;179(10):7166-75.
Species: Human
Sample Types: Urine

Sepsis and pathophysiology of anthrax in a nonhuman primate model.
Authors: Stearns-Kurosawa DJ, Lupu F, Taylor FB, Kinasewitz G, Kurosawa S
Am. J. Pathol., 2006;169(2):433-44.
Species: Primate - Papio cynocephalus (Yellow Baboon)
Sample Types: Plasma

Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing.
Authors: Anderson ST, Williams AJ, Brown JR, Newton SM, Simsova M, Nicol MP, Sebo P, Levin M, Wilkinson RJ, Wilkinson KA
Am. J. Respir. Crit. Care Med., 2006;173(9):1038-42.
Species: Human
Sample Types: Cell Culture Supernates

Increased ENA-78 in the follicular fluid of patients with endometriosis.
Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
Acta Obstet Gynecol Scand, 2006;85(3):336-42.
Species: Human
Sample Types: Follicular Fluid

B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease.
Authors: Kawai T, Matsuyama T, Hosokawa Y, Makihira S, Seki M, Karimbux NY, Goncalves RB, Valverde P, Dibart S, Li YP, Miranda LA, Ernst CW, Izumi Y, Taubman MA
Am. J. Pathol., 2006;169(3):987-98.
Species: Human
Sample Types: Tissue Homogenates

Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
J. Pharmacol. Exp. Ther., 2006;318(2):741-50.
Species: Human
Sample Types: Cell Culture Supernates

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
Eur. J. Immunol., 2005;35(8):2459-70.
Species: Human
Sample Types: Cell Culture Supernates

Adherence influences monocyte responsiveness to interleukin-10.
Authors: Petit-Bertron AF, Fitting C, Cavaillon JM, Adib-Conquy M
J. Leukoc. Biol., 2003;73(1):145-54.
Species: Human
Sample Types: Cell Culture Supernates

Differential effect of serotonin on cytokine production in lipopolysaccharide-stimulated human peripheral blood mononuclear cells: involvement of 5-hydroxytryptamine2A receptors.
Authors: Cloez-Tayarani I, Petit-Bertron AF, Venters HD, Cavaillon JM
Int. Immunol., 2003;15(2):233-40.
Species: Human
Sample Types: Cell Culture Supernates

Comparison of inflammatory elements in nasal lavage and induced sputum following occupational exposure to moldy-building microbes.
Authors: Purokivi M, Hirvonen MR, Roponen M, Randell J, Vahteristo M, Tukiainen H
Inhal Toxicol, 2002;14(6):653-62.
Species: Human
Sample Types: Sputum

IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions.
Authors: Cheong YC, Shelton JB, Laird SM, Richmond M, Kudesia G, Li TC, Ledger WL
Hum. Reprod., 2002;17(1):69-75.
Species: Human
Sample Types: Peritoneal Fluid

The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
Hum. Reprod., 2002;17(4):1039-45.
Species: Human
Sample Types: Peritoneal Fluid

Inflammatory mediators in nasal lavage, induced sputum and serum of employees with rheumatic and respiratory disorders.
Authors: Roponen M, Kiviranta J, Seuri M, Tukiainen H, Myllykangas-Luosujarvi R, Hirvonen MR
Eur. Respir. J., 2001;18(3):542-8.
Species: Human
Sample Types: Serum