Human LRP-1 Beta Subunit Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB6360V Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB6360V-100UG

Save 15% on Select RUO Reagents. See Details.

All LRP-1 Antibodies

Product Details

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human LRP-1 Beta Subunit Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human LRP-1 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG2b Clone # 545503

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human LRP-1
Gln4449-ala4544
Accession # Q07954

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: LRP-1

LRP-1 (low-density lipoprotein receptor-related protein 1) is a large type I transmembrane protein belonging to the LDL receptor superfamily. The extracellular domain of LRP-1 is organized in four clusters of ligand-binding repeats that recognizes at least 30 different ligands. The amino acid sequence of human and mouse LRP-1 cluster II share 100% identity. LRP-1 is an endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. It plays a crucial role in early embryonic development.

Long Name

LDL Receptor-related Protein 1

Entrez Gene IDs

4035 (Human)

Alternate Names

A2MR; Alpha-2-Macroglobulin Receptor; APOER; Apolipoprotein E receptor; APR; CD91 antigen; CD91; EC 1.1.1.94; EC 3.4.21.9; IGFBP3R; low density lipoprotein receptor-related protein 1; LRP; LRP-1; LRP1A; prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor