Human/Mouse Integrin alpha 11 Antibody
Human/Mouse Integrin alpha 11 Antibody Summary
Phe23-Pro1142 (Leu972Pro, Val1030 del)
Accession # EAW77820
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Human Integrin alpha 11 by Western Blot. Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line and human heart tissue. PVDF membrane was probed with 2 µg/mL of Human/Mouse Integrin a11 Monoclonal Antibody (Catalog # MAB4235) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for Integrin a11 at approximately 150 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.
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Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Integrin alpha 11
Integrin alpha 11 (ITGA11) is a 150 kDa transmembrane glycoprotein that associates with the Integrin beta 1/CD29 chain to form a receptor for collagen I and IX. ITGA11 is most highly expressed in adult cardiac and uterine smooth muscle and developing myocytes. The extracellular region contains seven FG-GAP repeats and one VWF‑C domain. Within the extracellular domain, human and mouse ITGA11 share 90% aa sequence identity.
Product Datasheets
Citations for Human/Mouse Integrin alpha 11 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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COL1A1 expression induced by overexpression of both a 15?amino acid peptide from the fibrinogen domain of tenascin?X and integrin alpha11 in LX?2 cells
Authors: KI Matsumoto, K Kawakami, K Yamada, H Takeshita
Molecular Medicine Reports, 2022;26(5):.
Species: Human
Sample Types: Protein
Applications: Western Blot -
A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency
Authors: AK Tharkeshwa, J Trekker, W Vermeire, J Pauwels, R Sannerud, DA Priestman, D Te Vruchte, K Vints, P Baatsen, JP Decuypere, H Lu, S Martin, P Vangheluwe, JV Swinnen, L Lagae, F Impens, FM Platt, K Gevaert, W Annaert
Sci Rep, 2017;7(0):41408.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis
Nat Commun, 2016;7(0):12502.
Species: Rat
Sample Types: Cell Lysates
Applications: Western Blot -
Cardiomyocyte contractile status is associated with differences in fibronectin and integrin interactions.
Authors: Wu X, Sun Z, Foskett A
Am. J. Physiol. Heart Circ. Physiol., 2010;298(6):H2071-81.
Species: Mouse
Sample Types: Whole Cells
Applications: Control
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Heart tissue lysates
