Human/Mouse Integrin  alpha 11 Antibody

Catalog # Availability Size / Price Qty
Detection of Human Integrin  alpha 11 by Western Blot.
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Product Details
Citations (4)
Supplemental Products
Reviews (1)

Human/Mouse Integrin  alpha 11 Antibody Summary

Species Reactivity
Human, Mouse
Detects human and mouse Integrin alpha 11 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human Integrin alpha 2, alpha 10, alpha X, or alpha L.
Monoclonal Rat IgG1 Clone # 396214
Protein A or G purified from hybridoma culture supernatant
Chinese hamster ovary cell line CHO-derived recombinant human Integrin  alpha 11
Phe23-Pro1142 (Leu972Pro, Val1030 del)
Accession # EAW77820
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
2 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human Integrin a11 antibody by Western Blot. View Larger

Detection of Human Integrin alpha 11 by Western Blot. Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line and human heart tissue. PVDF membrane was probed with 2 µg/mL of Human/Mouse Integrin a11 Monoclonal Antibody (Catalog # MAB4235) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for Integrin a11 at approximately 150 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Integrin alpha 11

Integrin alpha 11 (ITGA11) is a 150 kDa transmembrane glycoprotein that associates with the Integrin beta 1/CD29 chain to form a receptor for collagen I and IX. ITGA11 is most highly expressed in adult cardiac and uterine smooth muscle and developing myocytes. The extracellular region contains seven FG-GAP repeats and one VWF‑C domain. Within the extracellular domain, human and mouse ITGA11 share 90% aa sequence identity.

Entrez Gene IDs
22801 (Human); 319480 (Mouse); 315744 (Rat)
Alternate Names
HsT18964; Integrin alpha 11; integrin alpha-11; integrin, alpha 11; ITGA11

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Citations for Human/Mouse Integrin  alpha 11 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. COL1A1 expression induced by overexpression of both a 15?amino acid peptide from the fibrinogen domain of tenascin?X and integrin alpha11 in LX?2 cells
    Authors: KI Matsumoto, K Kawakami, K Yamada, H Takeshita
    Molecular Medicine Reports, 2022;26(5):.
    Species: Human
    Sample Types: Protein
    Applications: Western Blot
  2. A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency
    Authors: AK Tharkeshwa, J Trekker, W Vermeire, J Pauwels, R Sannerud, DA Priestman, D Te Vruchte, K Vints, P Baatsen, JP Decuypere, H Lu, S Martin, P Vangheluwe, JV Swinnen, L Lagae, F Impens, FM Platt, K Gevaert, W Annaert
    Sci Rep, 2017;7(0):41408.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  3. PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis
    Nat Commun, 2016;7(0):12502.
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Western Blot
  4. Cardiomyocyte contractile status is associated with differences in fibronectin and integrin interactions.
    Authors: Wu X, Sun Z, Foskett A
    Am. J. Physiol. Heart Circ. Physiol., 2010;298(6):H2071-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control


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Human/Mouse Integrin  alpha 11 Antibody
By Anonymous on 12/06/2021
Application: WB Sample Tested: Heart tissue Species: Mouse

Heart tissue lysates