Human/Mouse/Rat NKX2.2 Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB8167X Datasheet / COA / SDS

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FAB8167X-100UG

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All NKX2.2 Antibodies

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Human/Mouse/Rat NKX2.2 Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human NKX2.2 in ELISA and Western Blot.

Source

Monoclonal Mouse IgG2b Clone # 883411

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human NKX2.2
Met1-Lys128
Accession # O95096

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: NKX2.2

NKX2.2, also known as NKX2-2 or NKX2B, is an approximately 30 kDa, 273 amino acid homeobox nuclear transcription factor of the NKX2 protein family. It specifies differentiation of pancreatic islet cells such as alpha, beta, PP, and epsilon lineages. It also functions in developmental neuronal patterning of the ventral spinal cord in response to graded Sonic Hedgehog gradients and contributes pathfinding of commissural neurons. Within the region used as an immunogen, human NKX2.2 shares 96% and 97% amino acid sequence identity with mouse and rat NKX2.2, respectively.

Long Name

NK2 Homeobox 2

Entrez Gene IDs

4821 (Human); 18088 (Mouse); 366214 (Rat)

Alternate Names

Homeobox protein NK-2 homolog B; NK-2 (Drosophila) homolog B; NK2 homeobox 2; NK2 transcription factor related, locus 2 (Drosophila); NK2 transcription factor related, locus 2; NK2 transcription factor-like protein B; NKX2.2; NKX2.2homeobox protein Nkx-2.2; NKX2B; NKX2BNK-2 homolog B