Human/Mouse SOX2 PE-conjugated Antibody
Human/Mouse SOX2 PE-conjugated Antibody Summary
Gly135-Met317
Accession # P48431
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of SOX2 in NTera‑2 Human Cell Line by Flow Cytometry. NTera-2 human testicular embryonic carcinoma cell line was stained with Mouse Anti-Human/Mouse SOX2 PE-conjugated Monoclonal Antibody (Catalog # IC2018P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: SOX2
SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-6).
- Graham, V. et al. (2003) Neuron 39:749.
- Avilion, A.A. et al. (2003) Genes Dev. 17:126.
- Kishi, M. et al. (2000) Development 127:791.
- Yuan, H. et al. (1995) Genes Dev. 9:2635.
- Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
- Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Product Datasheets
Citations for Human/Mouse SOX2 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 7
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Generation of the induced human pluripotent stem cell lines CSSi009-A from a patient with a GNB5 pathogenic variant, and CSSi010-A from a CRISPR/Cas9 engineered GNB5 knock-out human cell line
Authors: N Malerba, P Benzoni, GM Squeo, R Milanesi, F Giannetti, LG Sadleir, G Poke, B Augello, AI Croce, A Barbuti, G Merla
Stem Cell Res, 2019;40(0):101547.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Derivation of human induced pluripotent stem cell line EURACi004-A from skin fibroblasts of a patient with Arrhythmogenic Cardiomyopathy carrying the heterozygous PKP2 mutation c.2569_3018del50
Authors: B Ermon, CB Volpato, G Cattelan, R Silipigni, M Di Segni, C Cantaloni, M Casella, PP Pramstalle, G Pompilio, E Sommariva, V Meraviglia, A Rossini
Stem Cell Res, 2018;32(0):78-82.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of human erythroblast-derived iPSC line using episomal reprogramming system
Authors: E Varga, M Hansen, T Wüst, M von Linder, E van den Ak
Stem Cell Res, 2017;25(0):30-33.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene
Authors: V Meraviglia, P Benzoni, S Landi, C Murano, M Langione, BM Motta, S Baratto, R Silipigni, M Di Segni, PP Pramstalle, D DiFrancesc, E Gazzerro, A Barbuti, A Rossini
Stem Cell Res, 2017;27(0):25-29.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mitochondrial role in adaptive response to stress conditions in preeclampsia
Sci Rep, 2016;6(0):32410.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
A single-cell and feeder-free culture system for monkey embryonic stem cells.
Authors: Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, Kato H, Torii R, Sato N
PLoS ONE, 2014;9(2):e88346.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: Flow Cytometry -
Patients with multiple myeloma develop SOX2-specific autoantibodies after allogeneic stem cell transplantation.
Authors: Kobold S, Tams S, Luetkens T, Cao Y, Sezer O, Bartels B, Reinhard H, Templin J, Bartels K, Hildebrandt Y, Lajmi N, Marx A, Haag F, Bokemeyer C, Kroger N, Atanackovic D
Clin Dev Immunol, 2011;2011(0):302145.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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